Results 201 to 210 of about 17,074,019 (238)
Inhibitory kappa B kinase-β is a target for specific nuclear factor kappa B-mediated delayed cardioprotection [PDF]
Journal of Thoracic and Cardiovascular Surgery, 2008 ObjectiveMyocardial ischemia/reperfusion injury remains a vexing problem. Translating experimental strategies that deliver protective agents before the ischemic insult limits clinical applicability. We targeted 2 proteins in the nuclear factor-κB pathway,
Craig Selzman, Albert Baldwin
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The cannabinoid dexanabinol is an inhibitor of the nuclear factor-kappa B (NF-κB)
Neuropharmacology, 2004Exogenous and endogenous cannabinoids have been shown to have neuroprotective effects in vitro and in vivo. Although many of the pharmacological effects of cannabinoids have been identified, the mechanism of neuroprotection still represents a controversy. Here we demonstrate for the first time protective effects of the synthetic cannabinoid dexanabinol
Eric, Jüttler +6 more
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The nuclear factor‐κB/inhibitor of kappa B autoregulatory system and atherosclerosis
Current Opinion in Lipidology, 1998Nuclear factor-kappa B is a ubiquitous transcription factor that can be activated by diverse proatherogenic stimuli such as inflammatory cytokines, lipopolysaccharide, oxidant stress and physical forces. Recently, there have been major advances in understanding signal transduction from the tumor necrosis factor receptor, a model activator of the ...
B L, Thurberg, T, Collins
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[Nuclear transcription factor kappa B (NF-kappa B)].
La Revue de medecine interne, 1999The transcription factor NF-kappa B is a key regulator of genes involved in responses to infection, inflammation and stress. It was first identified as a protein with ADN-binding activity specific for the 10-base-pair kappa B site in the immunoglobulin k light-chain enhancer of B lymphocytes.NF-kappa B is normally present in the cell cytoplasm bound to
P, Mercié +4 more
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Nuclear factor kappa B signaling in catabolic disorders
Current Opinion in Clinical Nutrition and Metabolic Care, 2002The nuclear factor kappa B family of inducible transcription factors regulates the expression of many genes. Nuclear factor kappa B has been implicated in autoimmune and inflammatory diseases, infection, cell survival, and cell transformation with subsequent promotion of cancer. In this review, we summarize features of nuclear factor kappa B regulation
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Nuclear Factor Kappa B: Important Transcription Factor and Therapeutic Target
The Journal of Clinical Pharmacology, 1998Nuclear factor kappa B (NF‐κB) is an ubiquitous rapid response transcription factor in cells involved in immune and inflammatory reactions, and exerts its effect by expressing cytokines, chemokines, cell adhesion molecules, growth factors, and immunoreceptors.
J I, Lee, G J, Burckart
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The Interaction of Nuclear Factor-Kappa B and Cytokines Is Associated with Schizophrenia
Biological Psychiatry, 2009Many reports suggest that schizophrenia is associated with the inflammatory response mediated by cytokines, and nuclear factor-kappa B (NF-kappaB) regulates the expression of cytokines. However, it remains unclear whether the interaction between NF-kappaB and cytokines is implicated in schizophrenia and whether the effect of neuroleptics treatment for ...
Xue-Qin, Song +4 more
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The international journal of biochemistry & cell biology, 1997
Nuclear factor-kappa B (NF-kappa B) is a ubiquitous transcription factor that, by regulating the expression of multiple inflammatory and immune genes, plays a critical role in host defence and in chronic inflammatory diseases. It is a heterodimer, present in the cytoplasm in an inactive form complexed to an inhibitory protein, I kappa B.
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Nuclear factor-kappa B (NF-kappa B) is a ubiquitous transcription factor that, by regulating the expression of multiple inflammatory and immune genes, plays a critical role in host defence and in chronic inflammatory diseases. It is a heterodimer, present in the cytoplasm in an inactive form complexed to an inhibitory protein, I kappa B.
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Nuclear factor-kappa B is constitutively activated in peritoneal endometriosis
MHR: Basic science of reproductive medicine, 2007Red (active), black and white endometriotic lesions are characteristic of peritoneal endometriosis. The transcription factor nuclear factor-kappa B (NF-kappaB) activates proinflammatory, proliferative and antiapoptotic genes in many cell types. To determine whether NF-kappaB is activated in peritoneal endometriosis in women, and further ascertain the ...
Reinaldo, González-Ramos +6 more
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The Role of Nuclear Factor Kappa B (NF-κB) in Development and Treatment of COVID-19: Review
International Journal of Molecular Sciences, 2022Barbara Mroczko +1 more
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