Results 241 to 250 of about 2,137,659 (362)

OCIAD2 Stabilizes Integrin β1 Signaling Through SNX17‐Mediated Endosomal Recycling to Lipid Rafts and Modulates Cisplatin Response in HNSCC

Advanced Science, EarlyView.
This study identifies OCIAD2 as a critical regulator of cisplatin resistance in HNSCC. Mechanistically, OCIAD2 stabilizes integrin β1 through a direct physical interaction and facilitates its SNX17‐dependent endosomal recycling to lipid raft microdomains. Targeting OCIAD2 disrupts integrin β1 trafficking and significantly enhances cisplatin sensitivity,
Li Cui, Shanshan Si, Min Ye, Pei Lin, Meiyan Zou, Yunfan Lin, Xu Chen, Bing Guo, Wenjuan Sun, Xinyuan Zhao   +9 more
wiley   +1 more source

HBV p22-interacting protein C1QBP inhibits viral replication through impeding nucleocapsid formation and nuclear import. [PDF]

PLoS Pathog
Peng X, Liu CD, Mitra B, Kim ES, Sun N, Jurado A, Zhang H, Li S, Zhou T, Guo H.   +9 more
europepmc   +1 more source

Structural basis for nuclear import of splicing factors by human Transportin 3

Proceedings of the National Academy of Sciences of the United States of America, 2014
G. Maertens, N. Cook, Weifeng Wang, S. Hare, Saumya Gupta, Ilker Öztop, Kyeongeun Lee, V. E. Pye, O. Cosnefroy, A. Snijders, V. KewalRamani, A. Fassati, A. Engelman, P. Cherepanov   +13 more
semanticscholar   +1 more source

A Versatile Three Dimensional Traction Force Microscopy Framework for Uncovering the Mechanics of Bio‐Adhesion

Advanced Science, EarlyView.
This study introduces a versatile platform for quantifying three dimensional traction forces at bio‐adhesive interfaces. Integrating in situ stereo‐digital image correlation with finite element simulations allows for precise measurement of microscale displacements and traction forces in both dry and wet conditions.
Yingwei Hou, Fusheng Wang, Tao Liu
wiley   +1 more source

DEAD-box helicase gcDDX56 disrupts IRF3 nuclear import complex and promotes nuclear IRF3 degradation for enhancing GCRV replication. [PDF]

J Virol
Xiao LL, Chen Y, Zhang J, Xiao J, Feng H, Chang MX.   +5 more
europepmc   +1 more source

Label-free imaging of nuclear membrane for analysis of nuclear import of viral complexes. [PDF]

J Virol Methods, 2023
Ten Eyck A, Chen YC, Gifford L, Torres-Rivera D, Dyer EL, Melikyan GB.   +5 more
europepmc   +1 more source

Supplementary Figure 5. from Low-Dose Paclitaxel Reduces S100A4 Nuclear Import to Inhibit Invasion and Hematogenous Metastasis of Cholangiocarcinoma

, 2023
Massimiliano Cadamuro, Gaia Spagnuolo, Luisa Sambado, Stefano Indraccolo, Giorgia Nardo, Antonio Rosato, Simone Brivio, Chiara Caslini, Tommaso Stecca, Marco Massani, Nicolò Bassi, Eugenio Novelli, Carlo Spirlı̀, Luca Fabris, Mario Strazzabosco   +14 more
openalex   +1 more source

Synthesis and assembly of mitochondrial proteins [PDF]

, 1988
Das, Rathindra C., Neupert, Walter, Nicholson, Donald W., Robbins, P. W.   +3 more
core   +1 more source

GbWAKL20 Phosphorylates GbNFYB8 to Modulate Verticillium Wilt Resistance in Cotton

Advanced Science, EarlyView.
Wall‐associated receptor‐like kinases (WAKLs) play pivotal roles in extracellular–intracellular signal transduction. Upon sensing Verticillium dahliae infestation at the plasma membrane, GbWAKL20 accumulates and transmits signals to the nucleus via endoplasmic reticulum‐mediated Golgi vesicle transport.
Guilin Wang, Qingxin Si, Zhiguo Chen, Zhe Yu, Zhan Guo, Lu Wang, Weixi Li, Wangzhen Guo   +7 more
wiley   +1 more source

Nemo-like kinase disrupts nuclear import and drives TDP43 mislocalization in ALS. [PDF]

J Clin Invest
Bekier ME, Pinarbasi E, Krishnan G, Mesojedec JJ, Hurley M, Harikumar Sheela H, Collins CA, Ghaffari L, de Majo M, Ullian EM, Koontz M, Coleman S, Li X, Tank EM, Waksmacki J, Gao FB, Barmada SJ.   +16 more
europepmc   +1 more source