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Nuclear Import of DNA

2007
Although the nuclear import of DNA may not be a normal event in the cell, mechanisms do exist for its transport. Some of these have evolved over a billion years, as viruses and other pathogens have perfected ways to invade the host, while others appear to be fortuitous piracy, as in the case of the SV40 enhancer which binds to proteins on their way to ...
David A. Dean, Kerimi E. Gokay
openaire   +1 more source

Role of the Nuclear Transport Factor p10 in Nuclear Import

Science, 1996
The nuclear import factor p10 was cloned from Saccharomyces cerevisiae and found to be essential. The protein p10 can bind directly to several peptide repeat-containing nucleoporins. It also binds to the guanosine triphosphatase (GTPase) Ran in its guanosine diphosphate (GDP)-bound form and to karyopherin β ...
U, Nehrbass, G, Blobel
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The other nuclear import

Trends in Cell Biology, 1998
Abstract HUBER, J. et al . (1998) Snurportin1, an m 3 G-cap-specific nuclear import receptor with a novel domain structure EMBO J .
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Importance measures for nuclear waste repositories

Reliability Engineering & System Safety, 2000
Abstract Several importance measures are identified for possible use in the performance assessment of a high-level nuclear waste repository. These importance measures are based on concepts of importance used in system reliability analysis, but the concepts are modified and adapted to the special characteristics of the repository and similar passive ...
N. A. Eisenberg, B. Sagar
openaire   +1 more source

Characterization of the nuclear import of human MutLα

Molecular Carcinogenesis, 2005
AbstractDNA mismatch repair (MMR) is essential for the maintenance of replication fidelity. Its major task is to recognize mismatches as well as insertion/deletion loops of newly synthesized DNA strands. Although different players of human MMR have been identified, the regulation of essential steps of MMR is poorly understood.
A, Brieger   +7 more
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Nuclear Protein Import

2007
Entry into the eukaryotic cell nucleus occurs through multiple pathways involving specific targeting signals, and intracellular receptor molecules of the importin/karyopherin superfamily which recognise and dock the nuclear import substrates carrying these signals at the nuclear pore.
David A. Jans, Jade K. Forwood
openaire   +1 more source

Nuclear transport: a guide to import receptors

Trends in Cell Biology, 1992
After synthesis in the cytoplasm, nuclear proteins traverse the nuclear envelope as a result of the specific recognition of nuclear localization signals by import. Various approaches have now uncovered a range of proteins with at least some of the characteristics expected of import receptors. This article focuses on early steps in the nuclear import of
L, Yamasaki, R E, Lanford
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Nuclear Import in Vitro

1990
The eukaryotic cell, divided into several compartments, is faced with the problem of how to put macromolecules where they should be. For example, an mRNA molecule transcribed in the nucleus must move to the cytoplasm to be translated. Its protein product can either remain soluble in the cytoplasm or it can enter one of several different organelles or ...
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Nuclear import

Trends in Plant Science, 1996
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Nuclear import of glycoconjugates

Biology of the Cell, 1998
Eric Duverger   +4 more
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