Results 271 to 280 of about 2,137,659 (362)

Mitochondrial CircRNA CircMT‐RNR2 Safeguards Antioxidant Defense to Support Fibroblast Functions in Wound Repair

Advanced Science, EarlyView.
CircMT‐RNR2 promotes wound healing by enhancing fibroblast proliferation, migration, contraction, and extracellular matrix (ECM) production. It sustains mitochondrial redox balance by stabilizing the antioxidant protein PRDX3, thereby reducing ROS‐induced damage. In diabetic foot ulcers, hypoxia, hyperglycemia, and reduced FGF2 and EGF expression lower
Guanglin Niu, Jennifer Geara, Yongjian Chen, Lihua Luo, Yanwei Xiao, Zhuang Liu, Margaux Gaborieau, Ling Pan, Edmund Loh, Dongqing Li, Pehr Sommar, Aoxue Wang, Xiaowei Zheng, Ning Xu Landén   +13 more
wiley   +1 more source

Characterization of the nuclear import of the human CHD4-NuRD complex.

J Cell Sci, 2023
Hoffmeister H, Holzinger S, Dürr MS, Bruckmann A, Schindler S, Gröbner-Ferreira R, Depping R, Längst G.   +7 more
europepmc   +1 more source

Nuclear import of APOBEC3F-labeled HIV-1 preintegration complexes

Proceedings of the National Academy of Sciences of the United States of America, 2013
Ryan C Burdick, Wei-Shau Hu, V. Pathak
semanticscholar   +1 more source

IgG‐Bridging–Seeded Synergistic Aggregation of SARS‐CoV‐2 Spikes Underlies Potent Neutralization by a Low‐Affinity Antibody

Advanced Science, EarlyView.
Low‐affinity antibodies are frequently disregarded in discovery pipelines. This work reports P5‐1C8, a Class 1 SARS‐CoV‐2 antibody with weak trimer binding (KD‐to‐IC50 > 3700‐fold) yet potent neutralization of Omicron JN.1. Structural, biophysical, functional, and coarse‐grained simulations collectively demonstrate that transient inter‐spike IgG ...
Niannian Lv, Peng Chen, Xiaobin Dai, Hu Xu, Ziheng Li, Zelin Shan, Jinqian Li, Fenglin Guo, Yuanfang Chen, Jiayi Li, Yiqian Huang, Guizhi Dong, Yifan Jiang, Liang Chen, Xuanyu Nan, Hanjun Zhao, Kang Zhang, Shilong Fan, Yuanchen Dong, Dongsheng Liu, Xinquan Wang, Deli Huang, Xiaojing Pan, Chunying Chen, Zhihua Liu, Li‐Tang Yan, Qi Zhang, Linqi Zhang, Yuliang Zhao, Yuhe Renee Yang   +29 more
wiley   +1 more source

Temporal gating of nuclear import: How Merkel cell polyomavirus exploits the cell cycle for nuclear entry. [PDF]

PLoS Pathog
Wang K, Eady AN, Amaya I, Stanczak A, Spriggs CC.   +4 more
europepmc   +1 more source

Retrograde transfer RNA nuclear import provides a new level of tRNA quality control in Saccharomyces cerevisiae

Proceedings of the National Academy of Sciences of the United States of America, 2013
Emily B Kramer, A. Hopper
semanticscholar   +1 more source

AXL Promotes Ischemic Myelin Repair Through Alleviating Myelin Debris Deposition and Lipid Droplets Accumulation

Advanced Science, EarlyView.
Microglial AXL drives white matter repair after stroke by orchestrating the cleanup of myelin debris. Mechanistically, AXL signals through EGR1 to boost Smpd1 transcription, regulating sphingolipid metabolism and preventing lipid droplet toxicity. Restoring the pathway with ASM therapy mitigates damage, positioning AXL as a key node for therapeutic ...
Junqiu Jia, Yonghui Gan, Jia Li, Lilin Li, Hailan Meng, Min Sun, Lei Ye, Rui Mao, Xiang Cao, Shengnan Xia, Xinyu Bao, Renyuan Liu, Meijuan Zhang, Yun Xu   +13 more
wiley   +1 more source

The transmembrane nucleoporin Nup210 weakens HIV-1 infection via modulating late events of viral nuclear import. [PDF]

AIDS
Wang L, Li SM, Li X, Wu HS, Ma C, Wang DB, Zhang XE.   +6 more
europepmc   +1 more source

Nuclear import in permeabilized protoplasts from higher plants has unique features.

, 1996
Glenn R. Hicks, Harley M. S. Smith, Stéphane Lobréaux, Natasha V. Raikhel   +3 more
openalex   +2 more sources

Androgen Induces a Switch from Cytoplasmic Retention to Nuclear Import of the Androgen Receptor

Molecular and Cellular Biology, 2013
Li Ni, Ryan A. Llewellyn, C. T. Kesler, Joshua B. Kelley, Adam Spencer, Chelsi J. Snow, Leonard C Shank, B. Paschal   +7 more
semanticscholar   +1 more source