Results 61 to 70 of about 2,137,659 (362)
Retrovirology, 2009 Background The integrase (IN) of human immunodeficiency virus type 1 (HIV-1) has been implicated in different steps during viral replication, including nuclear import of the viral pre-integration complex.
Waigmann Elisabeth +6 more
doaj +1 more source
A novel homozygous mutation of the AIRE gene in an APECED patient from Pakistan: case report and review of the literature [PDF]
, 2018 Autoimmune-poly-endocrinopathy-candidiasis-ectodermal-dystrophy syndrome (APECED) is a rare monogenic recessive disorder caused by mutations in the autoimmune regulator (AIRE) gene.
Bellacchio, Emanuele +5 more
core +2 more sources
The Journal of Cell Biology, 2006 ![Graphic][1] Import time (red) decreases and efficiency (blue) increases with more importin β. Faster, better import is gained by increasing levels of the importin β nuclear transport receptor, according to Yang and Musser (page [951][2]).
openaire +1 more source
PLoS ONE, 2019 More than just a container for DNA, the nuclear envelope carries out a wide variety of critical and highly regulated cellular functions. One of these functions is nuclear import, and in this study we investigate how altering the levels of nuclear ...
Predrag Jevtić +3 more
doaj +1 more source
The gateway to chloroplast: re-defining the function of chloroplast receptor proteins [PDF]
, 2012 Chloroplast biogenesis often requires a tight orchestration between gene expression (both plastidial and nuclear) and translocation of similar to 3000 nuclear-encoded proteins into the organelle.
Bölter, Bettina +2 more
core +1 more source
The nucleoporin ELYS regulates nuclear size by controlling NPC number and nuclear import capacity
bioRxiv, 2019 How intracellular organelles acquire their characteristic sizes is a fundamental cell biological question. Given the stereotypical changes in nuclear size in cancer, it is particularly important to understand the mechanisms that control nuclear size in ...
P. Jevtić +5 more
semanticscholar +1 more source
PexRAP inhibits PRDM16-mediated thermogenic gene expression [PDF]
, 2017 How the nuclear receptor PPARγ regulates the development of two functionally distinct types of adipose tissue, brown and white fat, as well as the browning of white fat, remains unclear.
Dean, John M +8 more
core +3 more sources
Identification of Sequences Encoding Symbiodinium minutum Mitochondrial Proteins. [PDF]
, 2016 The dinoflagellates are an extremely diverse group of algae closely related to the Apicomplexa and the ciliates. Much work has previously been undertaken to determine the presence of various biochemical pathways within dinoflagellate mitochondria ...
Butterfield, Erin R. +2 more
core +4 more sources
Science Signaling, 2018 Inhibition of the acetyltransferase NAT10 rescues a nuclear import pathway in cells from Hutchinson-Gilford progeria syndrome patients. Rescuing premature aging Cells from patients with Hutchinson-Gilford progeria syndrome (HGPS) have defects in nuclear ...
D. Larrieu +5 more
semanticscholar +1 more source
Importin 7 and Nup358 promote nuclear import of the protein component of human telomerase.
PLoS ONE, 2014 In actively dividing eukaryotic cells, chromosome ends (telomeres) are subject to progressive shortening, unless they are maintained by the action of telomerase, a dedicated enzyme that adds DNA sequence repeats to chromosomal 3'end.
Cornelia Frohnert +4 more
doaj +1 more source