Results 201 to 210 of about 163,417 (257)

Reversal of Stress‐Induced PIEZO1 Elevation with Mechanically Adapted Epicardial Patch for Myocardial Infarction Treatment

Advanced Science, EarlyView.
This work identifies fine‐tuning the expression of PIEZO1 as a critical molecular mechanism underlying the treatment of myocardial infarction by mechanically adapted cardiac patches, which can support the clinical translation of cardiac patch devices.
Yuwen Lu, Sibo Jiang, Ting Shen, Yuan Zhang, Chengbin He, Yun Gao, Liyin Shen, Qiao Jin, Yuting Zhao, Ping Liang, Chaochen Wang, Hongjie Hu, Jin He, Kaicheng Deng, Shuo Wang, Yunhe Chen, Jun Ling, Yang Zhu, Lenan Zhuang   +18 more
wiley   +1 more source

High Specific Strength Eutectic High‐Entropy Alloy: Collaborative Effects of TRIP, TWIP, and Nanoprecipitation

Advanced Science, EarlyView.
This study has designed a novel CoCrNiAl eutectic high‐entropy alloy with a two‐level heterogeneous structure with extremely high strength. The high mechanical properties originate from the collaborative strengthening mechanisms, including TWIP, TRIP, and nanoprecipitation.
Z. Q. Wang, X. T. Li, Z. J. Zhang, Z. F. Zhang   +3 more
wiley   +1 more source

CCDC80 Protects against Aortic Dissection and Rupture by Maintaining the Contractile Smooth Muscle Cell Phenotype

Advanced Science, EarlyView.
Aortic dissection (AD) is accompanied by a decrease in CCDC80 in vascular smooth muscle cells (VSMCs). CCDC80 can interact with JAK2, and VSMC‐specific CCDC80 deficiency accelerates the progression of AD by activating the JAK2/STAT3 pathway involved in regulating the phenotype switching and function of VSMCs.
Qingqing Xiao, Yi Li, Bin Cai, Xiying Huang, Liang Fang, Feng Liang, Long Chen, Ke Xu, Weifeng Zhang, Xiaolei Wang, Anwen Yin, Xia Wang, Zhaohua Cai, Fei Zhuang, Qin Shao, Bin Zhou, Berthold Hocher, Ben He, Linghong Shen   +18 more
wiley   +1 more source

Faculty Opinions recommendation of The nuclear lamina regulates germline stem cell niche organization via modulation of EGFR signaling.

, 2013
Jan Lammerding
openalex   +1 more source

Attenuated Nuclear Tension Regulates Progerin‐Induced Mechanosensitive Nuclear Wrinkling and Chromatin Remodeling

Advanced Science, EarlyView.
The premature aging‐related progerin leads to defective nuclear morphology and is associated with disrupted molecular coupling between the extranuclear cytoskeleton and lamin‐associated nuclear envelope. It is discovered that progerin expression reduces nuclear tension, forms nuclear wrinkling, and enhances chromatin dynamics, thereby regulating ...
Ji‐Eun Park, Juhyeon Jo, Kun Xu, Sun‐Ah Lee, Seong‐Beom Han, YigJi Lee, Won‐Ki Cho, Bo Li, Soo Hyun Kim, Dong‐Hwee Kim   +9 more
wiley   +1 more source

Faculty Opinions recommendation of Nuclear lamins are not required for lamina-associated domain organization in mouse embryonic stem cells.

, 2015
Martin W. Hetzer
openalex   +2 more sources

Plasmonic Molecular Entrapment for Label‐Free Methylated DNA Detection and Machine‐Learning Assisted Quantification

Advanced Science, EarlyView.
Plasmonic molecular entrapment (PME) is label‐free detection and quantification method for DNA methylation. This technique provides direct hotspot site generation around target analytes, overcoming mismatch geometrical properties. The PME demonstrates superior SERS performance and quantification capability, offering promising potential for epigenetic ...
Muhammad Shalahuddin Al Ja'farawy, Vo Thi Nhat Linh, Chaewon Mun, Jun‐Yeong Yang, Jun Young Kim, Rowoon Park, Sung‐Gyu Park, Dong‐Ho Kim, Min‐Young Lee, Ho Sang Jung   +9 more
wiley   +1 more source

From Ancient Techniques to Modern Solutions: In Situ Synthesis of C‐S‐H for Sandstone Conservation

Advanced Science, EarlyView.
Herein, this work presents a paleo‐inspired approach to synthesizing and optimizing C‐S‐H‐based grouting mortars for conserving the sandstone of Beishan Grottoes, Dazu Rock Carvings, China. By achieving an optimal recipe compatible with natural sandstone, this work demonstrates the pivotal role of hydrogen bonding in the adhesion between C‐S‐H mortars ...
Mengjun Jia, Huimin Yan, Qingqing Xu, Celestino Grifa, Gang Zhao, Siwei Jiang, Jinhua Wang, Zhenhua Wei, Han Liu, Xiao Ma   +9 more
wiley   +1 more source

The nexus of nuclear envelope dynamics, circular economy and cancer cell pathophysiology

European Journal of Cell Biology
The nuclear envelope (NE) is a critical component in maintaining the function and structure of the eukaryotic nucleus. The NE and lamina are disassembled during each cell cycle to enable an open mitosis.
Kristina Keuper, Jiri Bartek, Apolinar Maya-Mendoza   +2 more
doaj  

Bioinspired Liquid‐Free Ion‐Conductive Elastomers with Ultrahigh Mechanical Strength and Excellent Ionic Conductivity for Multifunctional Flexible Sensing Applications

Advanced Science, EarlyView.
⁻Inspired by the “brick wall” structure of pearl layer, FLICE‐110% liquid‐free ionic conductive elastomer had high mechanical strength (5.46 MPa), excellent ionic conductivity (3.29 × 10−4 S cm−1) and resilience. It can be used in smart music boxes, airplane wings and control manipulators.
Zequan Li, Jingjing Tang, Xuwei Wang, Fuqi Wang, Fangyan Ou, Wenyu Pan, Changsheng Wang, Ting Xie, Chuang Ning, Xiwei Xu, Jiamin Liu, Qihua Liang, Wei Gao, Shuangliang Zhao   +13 more
wiley   +1 more source