Results 221 to 230 of about 1,508,553 (267)
A novel strategy features gradient composition and stacking fault energy‐tuned (CoCrMn)100‐2xFexNix fabricated via in situ alloying additive manufacturing. This design circumvents cryogenic discontinuous plastic flow and hydrogen embrittlement of metallic materials under quasi‐static loading and hydrogen‐rich environment relevant to lunar polar ...
Renhao Wu +11 more
wiley +1 more source
Recent advances in metasurface‐enabled low‐observable technologies are reviewed from the perspective of cross‐scale material–structure synergy. Electromagnetic, thermal, optical, and acoustic stealth are highlighted together with dynamic tuning, programmable coding, data‐driven inverse design, artificial intelligence, multispectral compatibility, and ...
Shuhao Wang +5 more
wiley +1 more source
Ferroionic Electrostatic Landscapes Enabling Wireless Energy Harvesting, Storage, and Sensing
By integrating experiments and electrostatic field simulations, we show that long‐range wireless coupling in Li‐based ferroionics devices emerges from the cooperative interaction between ionic migration and electronic polarization. This coupling sustains self‐polarized electrostatic fields across centimeter‐scale air gaps without external bias or ...
M. Helena Braga +7 more
wiley +1 more source
Genome - nuclear lamina interactions are multivalent and cooperative
Dauban L +11 more
europepmc +1 more source
The Nuclear Lamina as an Organizer of Chromosome Architecture [PDF]
The nuclear lamina (NL) is a meshwork of lamins and lamin-associated proteins adjoining the inner side of the nuclear envelope. In early embryonic cells, the NL mainly suppresses background transcription, whereas, in differentiated cell types, its disruption affects gene expression more severely.
Yuri Shevelyov, Sergey Ulianov
exaly +4 more sources
Nuclear lamina at the crossroads of the cytoplasm and nucleus [PDF]
The nuclear lamina is a protein meshwork that lines the nuclear envelope in metazoan cells. It is composed largely of a polymeric assembly of lamins, which comprise a distinct sequence homology class of the intermediate filament protein family. On the basis of its structural properties, the lamina originally was proposed to provide scaffolding for the ...
Larry Gerace
exaly +3 more sources
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The nuclear lamina comes of age
Nature Reviews Molecular Cell Biology, 2005Many nuclear proteins form lamin-dependent complexes, including LEM-domain proteins, nesprins and SUN-domain proteins. These complexes have roles in chromatin organization, gene regulation and signal transduction. Some link the nucleoskeleton to cytoskeletal structures, ensuring that the nucleus and centrosome assume appropriate intracellular positions.
Yosef, Gruenbaum +4 more
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The nuclear lamina and inherited disease
Trends in Cell Biology, 2002Inherited disorders of the nuclear lamina present some of the most intriguing puzzles in cell biology. Mutations in lamin A and lamin C - nuclear intermediate filament proteins that are expressed in nearly all somatic cells - cause tissue-specific diseases that affect striated muscle, adipose tissue and peripheral nerve or skeletal development.
Howard J, Worman, Jean-Claude, Courvalin
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Functional mechanisms and abnormalities of the nuclear lamina
Nature Cell Biology, 2021Alterations in nuclear shape are present in human diseases and ageing. A compromised nuclear lamina is molecularly interlinked to altered chromatin functions and genomic instability. Whether these alterations are a cause or a consequence of the pathological state are important questions in biology.
Adam Karoutas, Asifa Akhtar
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Mechanisms of nuclear lamina growth in interphase
Histochemistry and Cell Biology, 2016The nuclear lamina represents a multifunctional platform involved in such diverse yet interconnected processes as spatial organization of the genome, maintenance of mechanical stability of the nucleus, regulation of transcription and replication. Most of lamina activities are exerted through tethering of lamina-associated chromatin domains (LADs) to ...
Oxana A, Zhironkina +6 more
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