Results 1 to 10 of about 9,088 (303)
Interplay of Lamin A and Lamin B LADs on the Radial Positioning of Chromatin
Nucleus, 2019 Immunosuppressive drugs such as cyclosporin A (CsA) can elicit hepatotoxicity by affecting gene expression. Here, we address the link between CsA and large-scale chromatin organization in HepG2 hepatocarcinoma cells.
Philippe Collas, Annaël Brunet
exaly +3 more sources
Family resources and externalizing problem behaviors among “lads” in township junior high schools: the role of positive youth development and peers’ positive moral character [PDF]
Frontiers in PsychologyBackgroundGiven the increasing occurrence of gang-like violent incidents in township junior high schools, investigating strategies for reducing the externalizing problem behaviors of “lads” (peer groups characterized by disruptive and delinquent ...
Shuyan Gao, Mengmeng Xie
doaj +2 more sources
Queer Positionality and Researching University Lad Culture
Social Sciences, 2022 This paper reflects on my experiences as a queer researcher investigating the relationship between university lad culture and gender-related violence. Gender-related violence is analysed as a useful conceptual tool for considering lad culture, owing to ...
Annis Elizabeth Stenson
exaly +3 more sources
Peripheral chromatin remodeling at the center of zygotic genome activation [PDF]
Cell GenomicsPal and colleagues1 investigate the molecular regulation of LAD establishment in mouse preimplantation embryos. This study provides insights into the physiological remodeling of LADs, revealing that zygotic LADs may be, in fact, dispensable during the ...
Laure de Chancel, Jean-Léon Maître
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CoRR, 2023 The logical analysis of data, LAD, is a technique that yields two-class classifiers based on Boolean functions having disjunctive normal form (DNF) representation. Although LAD algorithms employ optimization techniques, the resulting binary classifiers or binary rules do not lead to overfitting. We propose a theoretical justification for the absence of
C. A. Jothishwaran +3 more
openaire +3 more sources
Restructuring of Lamina-Associated Domains in Senescence and Cancer
Cells, 2022 Induction of cellular senescence or cancer is associated with a reshaping of the nuclear envelope and a broad reorganization of heterochromatin. At the periphery of mammalian nuclei, heterochromatin is stabilized at the nuclear lamina via lamina ...
Aurélie Bellanger +3 more
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Genome Biology, 2022 Background Interactions of chromatin with the nuclear lamina via lamina-associated domains (LADs) confer structural stability to the genome. The dynamics of positioning of LADs during differentiation, and how LADs impinge on developmental gene expression,
Julia Madsen-Østerbye +3 more
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Frontiers in Education, 2022 Learning analytic dashboards (LADs) are data visualization systems that use dynamic data in digital learning environments to provide students, teachers, and administrators with a wealth of information about student’s engagement, experiences, and ...
Priya Kannan, Diego Zapata-Rivera
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Journal of the American College of Cardiology, 2020 Despite a healthy lifestyle, endurance athletes can develop obstructive coronary disease and require appropriate evaluation, medical and interventional therapies. A 58-year-old healthy male presented to the emergency department after a witnessed cardiac arrest while exercising at a gym.
Jennifer Frampton +3 more
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Mapping the micro-proteome of the nuclear lamina and lamina-associated domains
Life Science Alliance, 2021 The nuclear lamina provides structure to the nucleus and serves as an interface between the cytoskeleton and large heterochromatin domains called LADs. This study describes the microproteome of this LAD/lamina interface.
Xianrong Wong +6 more
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