Results 1 to 10 of about 5,268 (117)

Family resources and externalizing problem behaviors among “lads” in township junior high schools: the role of positive youth development and peers’ positive moral character [PDF]

open access: yesFrontiers in Psychology
BackgroundGiven the increasing occurrence of gang-like violent incidents in township junior high schools, investigating strategies for reducing the externalizing problem behaviors of “lads” (peer groups characterized by disruptive and delinquent ...
Shuyan Gao, Mengmeng Xie
doaj   +2 more sources

Peripheral chromatin remodeling at the center of zygotic genome activation [PDF]

open access: yesCell Genomics
Pal and colleagues1 investigate the molecular regulation of LAD establishment in mouse preimplantation embryos. This study provides insights into the physiological remodeling of LADs, revealing that zygotic LADs may be, in fact, dispensable during the ...
Laure de Chancel, Jean-Léon Maître
doaj   +2 more sources

Pseudomonas aeruginosa two-component system LadS/PA0034 regulates macrophage phagocytosis via fimbrial protein cupA1

open access: yesMBio
Pseudomonas aeruginosa is one of the most common nosocomial pathogens worldwide, known for its virulence, drug resistance, and elaborate sensor-response network. The primary challenge encountered by pathogens during the initial stages of infection is the
Xiaolong Guo   +2 more
exaly   +3 more sources

Restructuring of Lamina-Associated Domains in Senescence and Cancer

open access: yesCells, 2022
Induction of cellular senescence or cancer is associated with a reshaping of the nuclear envelope and a broad reorganization of heterochromatin. At the periphery of mammalian nuclei, heterochromatin is stabilized at the nuclear lamina via lamina ...
Aurélie Bellanger   +3 more
doaj   +1 more source

Local euchromatin enrichment in lamina-associated domains anticipates their repositioning in the adipogenic lineage

open access: yesGenome Biology, 2022
Background Interactions of chromatin with the nuclear lamina via lamina-associated domains (LADs) confer structural stability to the genome. The dynamics of positioning of LADs during differentiation, and how LADs impinge on developmental gene expression,
Julia Madsen-Østerbye   +3 more
doaj   +1 more source

Facilitating the Use of Data From Multiple Sources for Formative Learning in the Context of Digital Assessments: Informing the Design and Development of Learning Analytic Dashboards

open access: yesFrontiers in Education, 2022
Learning analytic dashboards (LADs) are data visualization systems that use dynamic data in digital learning environments to provide students, teachers, and administrators with a wealth of information about student’s engagement, experiences, and ...
Priya Kannan, Diego Zapata-Rivera
doaj   +1 more source

Mapping the micro-proteome of the nuclear lamina and lamina-associated domains

open access: yesLife Science Alliance, 2021
The nuclear lamina provides structure to the nucleus and serves as an interface between the cytoskeleton and large heterochromatin domains called LADs. This study describes the microproteome of this LAD/lamina interface.
Xianrong Wong   +6 more
doaj   +1 more source

Lamina-associated domains: peripheral matters and internal affairs

open access: yesGenome Biology, 2020
At the nuclear periphery, associations of chromatin with the nuclear lamina through lamina-associated domains (LADs) aid functional organization of the genome.
Nolwenn Briand, Philippe Collas
doaj   +1 more source

An Isochore Framework Underlies Chromatin Architecture. [PDF]

open access: yesPLoS ONE, 2017
A recent investigation showed the existence of correlations between the architectural features of mammalian interphase chromosomes and the compositional properties of isochores.
Kamel Jabbari, Giorgio Bernardi
doaj   +1 more source

The Pseudomonas aeruginosa reference strain PA14 displays increased virulence due to a mutation in ladS. [PDF]

open access: yesPLoS ONE, 2011
Pseudomonas aeruginosa is a pathogen that causes acute and chronic infections in a variety of hosts. The pathogenic potential of P. aeruginosa is strain-dependent. PA14 is a highly virulent strain that causes disease in a wide range of organisms, whereas
Helga Mikkelsen   +2 more
doaj   +1 more source

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