Results 11 to 20 of about 9,088 (303)

The Pseudomonas aeruginosa reference strain PA14 displays increased virulence due to a mutation in ladS. [PDF]

PLoS ONE, 2011
Pseudomonas aeruginosa is a pathogen that causes acute and chronic infections in a variety of hosts. The pathogenic potential of P. aeruginosa is strain-dependent. PA14 is a highly virulent strain that causes disease in a wide range of organisms, whereas
Helga Mikkelsen, Rachel McMullan, Alain Filloux   +2 more
doaj   +3 more sources

Lamina-associated domains: peripheral matters and internal affairs

Genome Biology, 2020
At the nuclear periphery, associations of chromatin with the nuclear lamina through lamina-associated domains (LADs) aid functional organization of the genome.
Nolwenn Briand, Philippe Collas
doaj   +1 more source

An Isochore Framework Underlies Chromatin Architecture. [PDF]

PLoS ONE, 2017
A recent investigation showed the existence of correlations between the architectural features of mammalian interphase chromosomes and the compositional properties of isochores.
Kamel Jabbari, Giorgio Bernardi
doaj   +1 more source

The relative abundance of languages: Neutral and non-neutral dynamics.

PLoS ONE, 2021
Credible estimates suggest that a large number of the nearly 7000 languages in the world could go extinct this century, a prospect with profound cultural, socioeconomic, and political ramifications. Despite its importance, we still have little predictive
Luís Borda-de-Água, Stephen P Hubbell
doaj   +1 more source

Designing LADs That Promote Sensemaking: A Participatory Tool

, 2022
International audienceLearning Analytics Dashboards (LADs) are data visualization tools built to empower teachers and learners to make purposeful decisions that impact the learning process.
Aubert, Olivier, Sadallah, Madjid, Iksal, Sébastien, Quelennec, Katia, Vermeulen, Mathieu, Venant, Rémi, Gilliot, Jean-Marie, Neyssensas, Laurent   +7 more
core   +1 more source

The Hybrid Histidine Kinase LadS Forms a Multicomponent Signal Transduction System with the GacS/GacA Two-Component System in Pseudomonas aeruginosa.

PLoS Genetics, 2016
In response to environmental changes, Pseudomonas aeruginosa is able to switch from a planktonic (free swimming) to a sessile (biofilm) lifestyle. The two-component system (TCS) GacS/GacA activates the production of two small non-coding RNAs, RsmY and ...
Gaël Chambonnier, Lorène Roux, David Redelberger, Firas Fadel, Alain Filloux, Melissa Sivaneson, Sophie de Bentzmann, Christophe Bordi   +7 more
doaj   +1 more source

Transcription start site‐level expression of thyroid transcription factor 1 isoforms in lung adenocarcinoma and its clinicopathological significance

The Journal of Pathology: Clinical Research, 2021
There are multiple transcription start sites (TSSs) in agreement with multiple transcript variants encoding different isoforms of NKX2‐1/TTF‐1 (thyroid transcription factor 1); however, the clinicopathological significance of each transcript isoform of ...
Kei Sano, Takuo Hayashi, Yoshiyuki Suehara, Masaki Hosoya, Kazuya Takamochi, Shinji Kohsaka, Satsuki Kishikawa, Monami Kishi, Satomi Saito, Fumiyuki Takahashi, Kazuo Kaneko, Kenji Suzuki, Takashi Yao, Muneaki Ishijima, Tsuyoshi Saito   +14 more
doaj   +1 more source

Is there an association between left atrial outpouching structures and recurrence of atrial fibrillation after catheter ablation?

PLoS ONE, 2022
ObjectiveThe aim of this study was to investigate the impact of left atrial diverticula (LADs), left sided septal pouches (LSSPs) and middle right pulmonary veins (MRPVs) on recurrent atrial fibrillation (rAF) in patients undergoing laser pulmonary vein ...
Erkan Celik, Nils Große Hokamp, Lukas Goertz, Wolfgang Fehske, Dinh Quang Nguyen, Lutz Lichtenberg, Robert Peter Reimer, David Maintz, Christoph Düber, Tobias Achenbach   +9 more
doaj   +1 more source

Nuclear Lamin B1 Interactions With Chromatin During the Circadian Cycle Are Uncoupled From Periodic Gene Expression

Frontiers in Genetics, 2019
Many mammalian genes exhibit circadian expression patterns concordant with periodic binding of transcription factors, chromatin modifications, and chromosomal interactions. Here we investigate whether chromatin periodically associates with nuclear lamins.
Annaël Brunet, Frida Forsberg, Qiong Fan, Thomas Sæther, Philippe Collas, Philippe Collas   +5 more
doaj   +1 more source

Strong interactions between highly dynamic lamina-associated domains and the nuclear envelope stabilize the 3D architecture of Drosophila interphase chromatin

Epigenetics & Chromatin, 2023
Background Interactions among topologically associating domains (TADs), and between the nuclear envelope (NE) and lamina-associated domains (LADs) are expected to shape various aspects of three-dimensional (3D) chromatin structure and dynamics; however ...
Igor S. Tolokh, Nicholas Allen Kinney, Igor V. Sharakhov, Alexey V. Onufriev   +3 more
doaj   +1 more source