Results 231 to 240 of about 1,508,553 (267)

Assembly-disassembly of the nuclear lamina

Current Opinion in Cell Biology, 1992
Recently, progress in the study of lamins has been made in three areas: signals required for targetting newly synthesized lamins to the correct subnuclear compartment have been identified; information on lamina assembly has been obtained from in vitro studies using bacterially expressed proteins; and a mechanistic explanation for how the nuclear lamina
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Immunological analysis of nuclear lamina proteins

Chromosoma, 1980
Antibodies have been obtained against specific fractions of the nuclear lamina from chick red blood cells. Immunofluorescent staining of acrylamide gels from nuclear lamina preparations revealed a spectrum of at least 8-10 proteins cross-reacting immunologically with each other.
R, Stick, P, Hausen
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The Role of the Nuclear Lamina in Cancer and Apoptosis

2014
Not long after the discovery of lamin proteins, it became clear that not all lamin subtypes are ubiquitously expressed in cells and tissues. Especially, A-type lamins showed an inverse correlation with proliferation and were thus initially called statins.
Broers, Jos, Ramaekers, Frans
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The Nuclear Lamina

1990
During interphase, eukaryotic cells are physically separated into a nuclear and a cytoplasmic compartment by a complex organelle, the nuclear envelope. The innermost layer of the nuclear envelope is a polymeric protein network (Fawcett, 1966; Fawcett, 1981) termed the nuclear lamina (NL) (Fig.
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A new model for nuclear lamina organization

Biochemical Society Transactions, 2008
Lamins are intermediate filament proteins that form a network lining the inner nuclear membrane. They provide mechanical strength to the nuclear envelope, but also appear to have many other functions as reflected in the array of diseases caused by lamin mutations.
Martin W, Goldberg, Jindriska, Fiserova, Irm, Huttenlauch, Reimer, Stick   +3 more
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Inner nuclear membrane proteins and the nuclear lamina

Journal of Cell Science, 2001
The nuclear lamina is a scaffolding structure at the nuclear periphery and is required for maintenance of nuclear shape, spacing of nuclear pore complexes, organization of heterochromatin, DNA replication, and regulation of transcription factors.
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The nuclear lamina and heterochromatin: a complex relationship

Biochemical Society Transactions, 2011
In metazoan cells, the heterochromatin is generally localized at the nuclear periphery, whereas active genes are preferentially found in the nuclear interior. In the present paper, we review current evidence showing that components of the nuclear lamina interact directly with heterochromatin, which implicates the nuclear lamina in a mechanism of ...
Erin M, Bank, Yosef, Gruenbaum
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Organization and modulation of nuclear lamina structure

Journal of Cell Science, 1984
ABSTRACT The nuclear lamina is a protein meshwork associated with the nucleoplasmic surface of the inner nuclear membrane, that is suggested to be important for organizing nuclear envelope and interphase chromosome architecture. To investigate the structural organization of the lamina, we have analysed rat liver nuclear envelopes by ...
L, Gerace, C, Comeau, M, Benson
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Nuclear lamina and regulation of nuclear envelofe structure

Proceedings, annual meeting, Electron Microscopy Society of America, 1987
The nuclear lamina is a protein meshwork that lines the nucleoplasmic surface of the nuclear envelope. In numerous higher eukaryotic cells, the lamina is known to contain a polymer of 1-3 major polypeptides (“lamins“) that form an insoluble supramolecular assembly during interphase.
Larry Gerace, Ueli Aebi, Brian Burke, Frank Suprynowicz   +3 more
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Relation between nuclear envelope and nuclear lamina in nuclear assemblyin vitro

Science in China Series C: Life Sciences, 1997
Xenopus laevis egg extracts cell-free nuclear assembly system was used as an experimental model to study the process of nuclear lamina assembly in nuclear reconstitution in vitro. The experimental results showed that lamin was involved in the nuclear assembly in vitro.
S, Cai, Z, Zhai
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