Results 71 to 80 of about 113,787 (272)

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

Advanced Functional Materials, EarlyView.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv, Haifu Sun, Wenxiang Tang, Yonggang Li, Zhonglai Qian, Lihui Hong, Chong Chen, Hongye Li, Jiaxiang Bai, Yusen Qiao, Mingming Liu   +10 more
wiley   +1 more source

Perturbations in 3D genome organization can promote acquired drug resistance

Cell Reports, 2023
Summary: Acquired drug resistance is a major problem in the treatment of cancer. hTERT-immortalized, untransformed RPE-1 cells can acquire resistance to Taxol by derepressing the ABCB1 gene, encoding for the multidrug transporter P-gP.
Anna G. Manjón, Stefano Giustino Manzo, Stefan Prekovic, Leon Potgeter, Tom van Schaik, Ning Qing Liu, Koen Flach, Daniel Peric-Hupkes, Stacey Joosten, Hans Teunissen, Anoek Friskes, Mila Ilic, Dorine Hintzen, Vinícius H. Franceschini-Santos, Wilbert Zwart, Elzo de Wit, Bas van Steensel, René H. Medema   +17 more
doaj   +1 more source

Analysis of the Electrochemical Stability of Sulfide Solid Electrolyte Dry Films for Improved Dry‐Processed Solid‐State Batteries

Advanced Functional Materials, EarlyView.
An adapted processing for solvent‐free argyrodite solid electrolyte films based on insights into degradation mechanisms of the widely used binder polytetrafluoroethylene is presented. By adapting the dry film processing, long‐term cycling in Si||NMC pouch cells is demonstrated over more than 1000 cycles with a capacity retention of more than 80%, and ...
Maria Rosner, Sahin Cangaz, Felix Hippauf, Susanne Dörfler, Burak Aktekin, Thomas Meyer, Anja Henss, Thomas Abendroth, Holger Althues, Jürgen Janek, Stefan Kaskel   +10 more
wiley   +1 more source

Alterations to nuclear architecture and genome behavior in senescent cells. [PDF]

, 2007
The organization of the genome within interphase nuclei, and how it interacts with nuclear structures is important for the regulation of nuclear functions.
Abney J.R., Agrelo R., Barboro P., Becker P.B., Bemiller P.M., Benn P.A., Berezney R., Bowman P.D., Bridger J.M., Bridger J.M., C. S. CLEMENTS, Campisi J., Chaly N., Chang K.S., Cremer T., de Lange T., Dell'Orco R.T., Dijkwel P.A., Ferbeyre G., Filesi I., Fisher A.G., Fleischer S., Goldman R.D., Gruenbaum Y., Haque F., Hernandez-Verdun D., Holliday R., Hozak P., I. R. KILL, I. S. MEHTA, J. M. BRIDGER, Kill I.R., Kreth G., Lezhava T., Li Y., M. FIGGITT, Mallette F.A., Manuelidis L., Mazin A.L., Mitsui Y., Mukherjee A.B., Nickerson J., Okabe J., Padiath Q.S., Pawelec G., Petrova N.V., Schardin M., Schulz L., Smilenov L.B., Strouboulis J., Tanabe H., van Driel R., Wang G.S.   +52 more
core   +1 more source

A Solvent‐Free, Dry‐Processed Li‐Ion Battery Enabled by Dual Binders and Nanostructured Aluminum Current Collectors

Advanced Functional Materials, EarlyView.
A dual‐binder dry‐processed electrode (DB‐DPE) combining PTFE and PVDF with a nanostructured Al current collector (NSA) forms a mechanically interlocked interface that significantly improves adhesion and reduces interfacial resistance. With an active material content as high as 96 wt.%, the NSA‐based DB‐DPE enables high‐mass‐loading operation (12.5 mAh
Seok Yun Kim, Tae‐Kyung Liu, Hae Seong Kim, Dong Hwan Wang, Jong Hyeok Park   +4 more
wiley   +1 more source

Cell Cycle Dynamics of the Nuclear Envelope

The Scientific World Journal, 2003
The nuclear envelope (NE) consists of an inner and an outer membrane, nuclear pore complexes, and the underlying nuclear lamina, a filamentous scaffold structure formed by lamins.
Roland Foisner
doaj   +1 more source

Physical constraints in polymer modeling of chromatin associations with the nuclear periphery at kilobase scale

Nucleus, 2021
Interactions of chromatin with the nuclear lamina imposes a radial genome distribution important for nuclear functions. How physical properties of chromatin affect these interactions is unclear.
Annaël Brunet, Nicolas Destainville, Philippe Collas   +2 more
doaj   +1 more source

Identification of genes expressed by immune cells of the colon that are regulated by colorectal cancer-associated variants. [PDF]

, 2013
A locus on human chromosome 11q23 tagged by marker rs3802842 was associated with colorectal cancer (CRC) in a genome-wide association study; this finding has been replicated in case-control studies worldwide. In order to identify biologic factors at this
Ash, Colleen, Beck, Timothy, Bielecki, Ryszard, Boutros, Paul C, Chan-Seng-Yue, Michelle, Chong, Taryne, D'Souza, David JA, De Borja, Richard, Dick, John E, Gallinger, Steven, Gryfe, Robert, Hodgson, Lyndsey, Hudson, Thomas J, Kozak, Krystian, Kwan, Jennifer YY, Lee, Shawna, Lemire, Mathieu, McPherson, John D, Peltekova, Vanya D, Pollett, Aaron, Qazi, Aamer M, Rangrej, Jagadish, Rogers, Marianne, Stein, Lincoln D, Timms, Lee, Trinh, Quang M, Volar, Milica, Wang, Jianxin, Wang, Mike, Zaidi, Syed HE, Zandi, Sasan, Zanke, Brent W   +31 more
core   +2 more sources

Immunopathogenesis of canine chronic ulcerative stomatitis. [PDF]

, 2020
Canine Chronic Ulcerative Stomatitis is a spontaneously occurring inflammatory disease of the oral mucosa. An immune-mediated pathogenesis is suspected though not yet proven.
Anderson, JG, Bizikova, P, Ford, K, Jimenez, RJ, Kol, A, Murphy, BG, Stapelton, BP, Vasilatis, D, Villarreal, A   +8 more
core   +1 more source

Solvent‐Free Bonding Mechanisms and Microstructure Engineering in Dry Electrode Technology for Lithium‐Ion Batteries

Advanced Functional Materials, EarlyView.
Dry electrode technology revolutionizes battery manufacturing by eliminating toxic solvents and energy‐intensive drying. This work details two promising techniques: dry spray deposition and polymer fibrillation. How their unique solvent‐free bonding mechanisms create uniform microstructures for thicker, denser electrodes, boosting energy density and ...
Yuhao Liang, Hao Long, Zimo Huang, Ting He, Xueming Chen, Meng Li, Hao Chen, Shanqing Zhang   +7 more
wiley   +1 more source