Real-time nuclear magnetic resonance spectroscopy in the study of biomolecular kinetics and dynamics [PDF]
Magnetic Resonance, 2021 The review describes the application of nuclear magnetic resonance (NMR) spectroscopy to study kinetics of folding, refolding and aggregation of proteins, RNA and DNA.
G. Pintér +6 more
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Curating Scientific Workflows for Biomolecular Nuclear Magnetic Resonance Spectroscopy
International Journal of Digital Curation, 2019 This paper describes our recent and ongoing efforts to enhance the curation of scientific workflows to improve reproducibility and reusability of biomolecular nuclear magnetic resonance (bioNMR) data.
Douglas Heintz, Michael R Gryk
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Metabolites, 2023 A detailed analysis of the elemental and molecular composition of Posidonia oceanica (PO) and Ascophyllum nodosum (AN) is presented. In particular, an in-depth study of the molecular identification via NMR spectroscopy of aqueous and organic extracts of ...
Angelica Bruno +5 more
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Quantification of Small Molecule Partitioning in a Biomolecular Condensate with 2D Nuclear Magnetic Resonance Spectroscopy. [PDF]
ChembiochemSeveral intrinsically disordered proteins have been shown to undergo phase separation into a dense and dilute phase and this process is intimately linked with the regulation of cellular processes. It is therefore highly relevant to know how metabolites partition between these phases.
Buhl JM +3 more
europepmc +4 more sources
Probing Biomolecular Interactions with Paramagnetic Nuclear Magnetic Resonance Spectroscopy. [PDF]
ChembiochemAbstractRecent advances in computational methods like AlphaFold have transformed structural biology, enabling accurate modeling of protein complexes and driving applications in drug discovery and protein engineering. However, predicting the structure of systems involving weak, transient, or dynamic interactions, or of complexes with disordered regions,
Busch H +5 more
europepmc +4 more sources
Nuclear Magnetic Resonance, a Powerful Tool for the Study of Biomolecular Dynamics
CHIMIA, 1997 . Several non-permanent polycations possessing substantial buffering capacity below physiological pH, such as lipopolyamines and polyethylenimines, are efficient transfection agents per se, i.e.
Richard R. Ernst
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Biophysics Reports, 2021 The assembly of biomolecular condensates is driven by liquid-liquid phase separation. To understand the structure and functions of these condensates, it is essential to characterize the underlying driving forces, e.g., protein-protein and protein-RNA interactions.
Zhang, Hanyu +9 more
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ssNMRlib: a comprehensive library and tool box for acquisition of solid-state nuclear magnetic resonance experiments on Bruker spectrometers [PDF]
Magnetic Resonance, 2020 We introduce ssNMRlib, a comprehensive suite of pulse sequences and jython scripts for user-friendly solid-state nuclear magnetic resonance (NMR) data acquisition, parameter optimization and storage on Bruker spectrometers.
A. Vallet +3 more
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Recent Advances in Solid-State Nuclear Magnetic Resonance Techniques to Quantify Biomolecular Dynamics [PDF]
Analytical Chemistry, 2013 The emergence of solid-state NMR (SSNMR) techniques over the last decade has greatly expanded the range of accessible biomolecules amenable to structural study.1-2 These methods were developed and first applied to a variety of microcrystalline model proteins including BPTI,3 SH3,4-5 ubiquitin,6-7 kaliotoxin,8 and GB1.9-11 These studies demonstrated ...
Eric D, Watt, Chad M, Rienstra
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Introduction to a special issue of Magnetic Resonance in honour of Robert Kaptein at the occasion of his 80th birthday [PDF]
Magnetic Resonance, 2021 This publication, in honour of Robert Kaptein's 80th birthday, contains contributions from colleagues, many of whom have worked with him, and others who admire his work and have been stimulated by his research.
R. Boelens +3 more
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