Results 91 to 100 of about 3,441,532 (219)

SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights

Annals of Clinical and Translational Neurology
Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far,
Nuria Muelas, Pablo Iruzubieta, Alberto Damborenea, Laura Pérez‐Fernández, Inmaculada Azorín, Juan Carlos Jiménez García, Ana Töpf, Pilar Martí, Lorena Fores‐Toribio, María Manterola, Rosana Blanco‐Mañez, Oihane Pikatza‐Menoio, Sonia Alonso‐Martín, Volker Straub, Aitziber L. Cortajarena, Adolfo López de Munain, David De Sancho, Lorea Blázquez, Juan J. Vilchez   +18 more
doaj   +1 more source

Biochemical methods for producing and characterising recombinant spider silks

Frontiers in Arachnid Science
Here, we review the processes involved in producing and assessing the quality of recombinant spider silk proteins (spidroins) and the challenges associated with their synthesis and spinning into robust fibres.
Anton Maraldo, Anton Maraldo, James H. Torpey, Sasha L. Evans, Aditya Rawal, Jeffery L. Yarger, Rivka L. Isaacson, Christopher P. Marquis, Christopher P. Marquis, Sean J. Blamires, Sean J. Blamires   +10 more
doaj   +1 more source

Magnetoelastic Cell Monitoring System for Evaluating the Effects of Surface Chemistry on the Performance of Mesenchymal Stem Cell Growth

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The recent clinical adoption of cell therapies has increased the need for more efficient, robust, and reproducible manufacturing technologies. Human mesenchymal stromal cells (hMSCs), a major component of the cell and immunotherapeutic market, remain challenging to manufacture at scale because they require surface attachment and are highly ...
William S. Skinner, Carolina Rivera‐Crespo, Eyerusalem A. Gebreyesus, Said Cifuentes, Samantha Tan, Tristen Douglas, Maribella Domenech‐Garcia, Keat Ghee Ong   +7 more
wiley   +1 more source

Exploring the structure and dynamics of peptide nanodiscs through a synergistic approach with NMR spectroscopy, SAS and MD simulations

Communications Chemistry
Peptide nanodiscs are promising anti-atherosclerosis therapeutics, drug delivery particles and structural biology tools. However, the lack of experimental methods for structural and dynamical characterization of these particles hinders their further ...
Sirine Nouri, Akseli Niemelä, Ricky Nencini, Georgios Kolypetris, Tuomas Niemi-Aro, Salla I. Virtanen, O. H. Samuli Ollila, Artturi Koivuniemi   +7 more
doaj   +1 more source

Nuclear Magnetic Resonance

Nuclear magnetic resonance (NMR) continues to revolutionize science, evolving constantly and generating an expansive body of literature. This expertly curated volume brings clarity to complexity, distilling recent advances across the full spectrum of NMR

core   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

The Inertness of the Lysozyme Template: Assessing the Structural Impact of Silicification Byproducts and Precursors

Chemistry–Methods
Bioinspired silica deposition with biomolecular templates offers a sustainable route to producing advanced inorganic materials. The templating agent is usually a polycation.
Tozivepi Aaron Munyayi, Francesco Bruno, Letizia Fiorucci, Vincenzo Mangini, Francesco Scattarella, Cinzia Giannini, Jose Malanho Da Silva, Giacomo Parigi, Angelo Gallo, Enrico Ravera   +9 more
doaj   +1 more source

Computational Chemistry in Nuclear Magnetic Resonance

Determining molecular structure via nuclear magnetic resonance (NMR) spectral analysis has become an integral part of physical–chemical research in organic and inorganic chemistry [...
Yuriy Yu. Rusakov, Irina L. Rusakova
core   +1 more source

Understanding the Pathogenesis of Neuroinflammation using Magnetic Resonance Imaging [PDF]

, 2011
A non-invasive view of the brain with the aid of magnetic resonance imaging (MRI) is invaluable for studying pathological processes during autoimmune encephalomyelitis.
Waiczies, Sonia, Waiczies, Helmar, Waiczies, H., Waiczies, S.   +3 more
core  

An all‐in‐one fucosylated gold nanocluster probe enables NIR‐II imaging and multi‐mechanistic therapy of acute kidney injury

BMEMat, EarlyView.
This study developed a fucoside‐targeted gold nanocluster probe that enables early NIR‐II imaging and multi‐mechanistic therapy for acute kidney injury, effectively mitigating oxidative stress, modulating inflammatory responses, and inhibiting ferroptosis to improve renal outcomes. Abstract Acute kidney injury (AKI) remains a life‐threatening condition
Ping Zhang, Boning Tan, Suqing Feng, Beibei Gu, Ting Feng, Haiguang Zhu, Jianping Xie, Xun Yuan   +7 more
wiley   +1 more source