Results 111 to 120 of about 345,890 (219)

Aryl‐Bridged Polysilsesquioxanes as Support for Aqueous Phase Catalytic Phenol Hydrogenation: Effect of Hydrophobicity and Organic Content of the Support

ChemCatChem, Accepted Article.
In this research, aryl‐bridged polysilsesquioxane (ABPS), an organosilica material, is used as support to synthesize an efficient palladium (Pd) catalyst for catalytic hydrogenation of phenol to cyclohexanone and cyclohexanol. Techniques such as N2 physisorption, NMR, IR, TEM, CO chemisorption were employed to characterize the support.
Umit S Ozkan, Anagha Hunoor, Snehal Patil, Nisha Iyer, Dan Coroy, Seval Gunduz, Paul Edmiston, Dan Conroy   +7 more
wiley   +1 more source

Effect of the Aromatic Content of Organosilica Supports on Aqueous Phase Phenol Hydrogenation

ChemCatChem, Accepted Article.
In this work, bridged polysilsesquioxanes with varying aromatic content were used as catalyst supports with active metal palladium (Pd) for aqueous phase phenol hydrogenation. Alkoxysilane precursors, bis (trimethoxy silyl ethyl) benzene (BTEB) and bis (tri methoxy silyl) ethane (BTE) were co‐condensed by sol‐gel synthesis to vary the aromatic content ...
Anagha Hunoor, Snehal Patil, Emily Naughton, James Nana Gyamfi, Chidimma Maryjane Nwankor, Dan Conroy, Tanay Jawdekar, Seval Gunduz, Paul Edmiston, Umit S Ozkan   +9 more
wiley   +1 more source

Recent developments in biosensing methods for extracellular vesicle protein characterization

WIREs Nanomedicine and Nanobiotechnology, Volume 15, Issue 1, January/February 2023., 2023
Various biosensing principles may serve for the detection and characterisation of extracellular vesicles. Herein, the key platform are systematically reviewed, with a focus on the most recent and fundamental developments. Abstract Research into extracellular vesicles (EVs) has grown significantly over the last few decades with EVs being widely regarded
Jugal Suthar, Marissa Taub, Randy P. Carney, Gareth R. Williams, Stefan Guldin   +4 more
wiley   +1 more source

Graphene Derivatives as Efficient Transducing Materials for Covalent Immobilization of Biocomponents in Electrochemical Biosensors

ChemElectroChem, EarlyView.
This review explores the transformative role of graphene derivatives in electrochemical biosensors for diagnostics, environmental monitoring, and industrial sensing. Highlighting innovations in synthesis and covalent functionalization, it discusses how these materials enhance biosensor stability, specificity, and scalability.
Petr Jakubec, David Panáček, Martin‐Alex Nalepa, Marianna Rossetti, Ruslan Álvarez‐Diduk, Arben Merkoçi, Majlinda Vasjari, Lueda Kulla, Michal Otyepka   +8 more
wiley   +1 more source

Pathway‐based integration of multi‐omics data reveals lipidomics alterations validated in an Alzheimer's disease mouse model and risk loci carriers

Journal of Neurochemistry, Volume 164, Issue 1, Page 57-76, January 2023., 2023
A genome‐scale model network was built for Alzheimer's disease (AD) using data from publicly available genome‐wide association studies in humans, and transcriptomics and proteomics data from brain tissue from mouse models of AD. The derived network was characterized by gene ontology, transcription factor analysis, and pathway and cell‐type enrichment ...
Monica Emili Garcia‐Segura, Brenan R. Durainayagam, Sonia Liggi, Gonçalo Graça, Beatriz Jimenez, Abbas Dehghan, Ioanna Tzoulaki, Ibrahim Karaman, Paul Elliott, Julian L. Griffin   +9 more
wiley   +1 more source

NMR Solution Structure of the N-Terminal GSPII Domain from the Thermus Thermophilus Traffic ATPase PilF and Reconstruction of its c-di-GMP Binding Capability. [PDF]

Chembiochem
GSPII‐A is the first of three consecutive GSPII domains of PilF from Thermus thermophilus and the only one that does not bind c‐di‐GMP. In this study we solve the structure of GSPII‐A and show the key factors hindering c‐di‐GMP binding. Through mutagenesis, we elucidate the minimal motif conservation needed for c‐di‐GMP recognition. Abstract The cyclic
Neißner K, Frohnapfel C, Keller H, Duchardt-Ferner E, Schneider V, Kamjou Z, Averhoff B, Wöhnert J.   +7 more
europepmc   +2 more sources

A Cytotoxic Indazole‐based Gold(III) Carboxamide Pincer Complex Targeting DNA Through Dual Binding Modes of Groove Binding and Alkylation

Chemistry – A European Journal, EarlyView.
Toward new gold(III) anticancer agents. Herein, we report on an indazole‐based gold(III) carboxamide pincer complex exhibiting significant cytotoxicity, likely mediated through dual interactions with DNA. Mechanistic investigations suggest that the complex binds to the DNA and forms specific interactions with nucleotide bases.
Rufaro Razuwika, Sheldon Sookai, Ruth Aronson, Mandeep Kaur, Orde Q. Munro   +4 more
wiley   +1 more source

Robust Self‐Healing Metallo‐Supergels of Folic Acid: Potential Sustainable Gelator for Oilfield Applications

Chemistry – A European Journal, EarlyView.
In combination with a large group of various metal salts folic acid (FA) forms mechanically robust metallogels with rapid recovery and self‐healing properties. These versatile gel systems provide tunable stiffness, with up to 95% of stiffness restored within 1 min.
Mahya Asgharian Marzabad, Subhasis Chattopadhyay, Sami Hietala, Nonappa Nonappa, Radek Marek, Ondřej Jurček   +5 more
wiley   +1 more source

Determination of factors controlling the particle size and entrapment efficiency of noscapine in PEG/PLA nanoparticles using artificial neural networks

International Journal of Nanomedicine, 2014
Karim S Shalaby,1 Mahmoud E Soliman,1 Luca Casettari,2 Giulia Bonacucina,3 Marco Cespi,3 Giovanni F Palmieri,3 Omaima A Sammour,1 Abdelhameed A El Shamy1,† 1Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Ain Shams ...
Shalaby KS, Soliman ME, Casettari L, Bonacucina G, Cespi M, Palmieri GF, Sammour OA, El Shamy AA   +7 more
doaj  

A Tetrazine‐Based Synthesis for Accessing Underutilized Aza‐Indole Analogues

Chemistry – A European Journal, EarlyView.
A nucleophilic aromatic substitution (SNAr)/Diels–Alder (DA)/retro Diels–Alder (rDA) reaction cascade has been developed to access pyrazolo[3,4‐c]pyridazine compounds. These cores have been further derivatized through divergent, late‐stage modifications to access various substitution patterns of the 3, 4, and 5 positions on the heterocyclic core ...
Evan Savelson, Katarina A. Selewski, Jetze J. Tepe   +2 more
wiley   +1 more source