Results 101 to 110 of about 2,248,811 (276)
Proteasomes tether to two distinct sites at the nuclear pore complex
Proceedings of the National Academy of Sciences of the United States of America, 2017 Significance This study compares the native structures of cytosolic and nuclear proteasomes, visualized directly within cells. The assembly states and functional states of proteasomes in each compartment were similar, indicating comparable levels of ...
S. Albert +9 more
semanticscholar +1 more source
Nuclear Pores: David and Goliath in nuclear transport [PDF]
Current Biology, 1995 AbstractThe small GTP-binding protein Ran has been implicated in protein import into, and mRNA export from, the nucleus. A recently identified ‘giant’ nuclear pore complex protein, Nup358, binds GTP–Ran.
openaire +3 more sources
Insights into Adenovirus Uncoating from Interactions with Integrins and Mediators of Host Immunity
Viruses, 2016 Human adenoviruses are large (150 MDa) nonenveloped double-stranded DNA (dsDNA) viruses that cause acute respiratory, gastrointestinal and ocular infections.
Glen R. Nemerow, Phoebe L. Stewart
doaj +1 more source
Enhanced surface interaction of water confined in hierarchical porous polymers induced by hydrogen bonding [PDF]
, 2016 Hierarchical porous polymer systems are increasingly applied to catalysis, bioengineering, or separation technology because of the versatility provided by the connection of mesopores with percolating macroporous structures.
Acosta, Rodolfo Hector +7 more
core +2 more sources
Nuclear pore assembly proceeds by an inside-out extrusion of the nuclear envelope
eLife, 2016 The nuclear pore complex (NPC) mediates nucleocytoplasmic transport through the nuclear envelope. How the NPC assembles into this double membrane boundary has remained enigmatic.
K. Weis +10 more
semanticscholar +1 more source
The Journal of Cell Biology, 2002 ![][1] During checkpoint activation, Mad1p (green) is at NPCs, not kinetochores (red). Two recent studies in mammalian cells have shown that spindle checkpoint proteins can be found at the nuclear pore during interphase and that nucleoporins localize to kinetochores during mitosis ...
openaire +3 more sources
CDK12 Activity-Dependent Phosphorylation Events in Human Cells
Biomolecules, 2019 We asked whether the C-terminal repeat domain (CTD) kinase, CDK12/CyclinK, phosphorylates substrates in addition to the CTD of RPB1, using our CDK12analog-sensitive HeLa cell line to investigate CDK12 activity-dependent phosphorylation events in human ...
Bartlomiej Bartkowiak +3 more
doaj +1 more source
Vaults. III. Vault ribonucleoprotein particles open into flower-like structures with octagonal symmetry. [PDF]
, 1991 The structure of rat liver vault ribonucleoprotein particles was examined using several different staining techniques in conjunction with EM and digestion with hydrolytic enzymes.
Chugani, DC +3 more
core +2 more sources
mSphere of Influence: the Dynamic Nature of the Nuclear Envelope during Mitosis of Malaria Parasites
mSphere, 2020 Sabrina Absalon works in the field of cellular and molecular biology of Plasmodium falciparum, the most virulent parasite causing malaria in humans. In this mSphere of Influence article, she reflects on how the paper “3D nuclear architecture reveals ...
Sabrina Absalon
doaj +1 more source
Traffic control at the nuclear pore [PDF]
Nucleus, 2010 The proper communication between organelles is essential for many aspects of eukaryotic life. The coordination of nuclear and cytoplasmic activities in particular is of pivotal importance and depends on transport in and out of the nucleus. The material which translocates through nuclear pores is diverse; it includes numerous proteins, RNAs and large ...
Mohamed Kodiha +4 more
openaire +3 more sources