Results 101 to 110 of about 326,922 (335)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Comparative study on pore size distribution in coal based on mercury intrusion-low temperature liquid nitrogen combined pore and nuclear magnetic resonance analysis

Meikuang Anquan
The pore structure measurement in coal is commonly analyzed by mercury intrusion method, low temperature liquid nitrogen method and nuclear magnetic resonance method. Due to the different test methods, the results cannot be used uniformly, and the matrix
Nana LI, Huihu LIU, Shuxun SANG
doaj   +1 more source

New Models for UO2 Fuel Structure Evolution under Irradiation in Fast Reactors

, 2011
On the base of analysis of experimental observations and critical assessment of existing models for oxide fuel structure evolution under operation conditions of fast reactors, new models for fuel restructuring and coring are proposed.
Bourgeois, Brook, Burke, Chubb, Clement, de Halas, Freund, M.S. Veshchunov, Maeda, McEwan, Nichols, Nichols, Ozawa, Ronchi, Sens, Shewmon, Speight, Turnbull, Veshchunov, Veshchunov, Veshchunov, Veshchunov, Yajima, Yanagisawa   +23 more
core   +1 more source

Segregation of yeast nuclear pores [PDF]

Nature, 2010
During mitosis in Saccharomyces cerevisiae, senescence factors such as extrachromosomal ribosomal DNA circles (ERCs) are retained in the mother cell and excluded from the bud/daughter cell. Shcheprova et al. proposed a model suggesting segregation of ERCs through their association with nuclear pore complexes (NPCs) and retention of pre-existing NPCs in
Anton, Khmelinskii, Philipp J, Keller, Holger, Lorenz, Elmar, Schiebel, Michael, Knop   +4 more
openaire   +2 more sources

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Molecular genetics of oogenesis in Drosophila melanogaster [PDF]

Invertebrate Survival Journal, 2004
Gonadal development requires complex differentiation programs leading to the production of functional female and male gametes. Upon fertilization, while the male germ cell contributes to the newly formed zygote only its genetic material, the female germ ...
S Gigliotti, V Cavaliere, G Gargiulo, F Graziani, C Malva   +4 more
doaj   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

The emerging use of magnetic resonance imaging to study river bed dynamics [PDF]

, 2015
The characterization of surface and sub-surface sedimentology has long been of interest to gravel-bed river researchers. The determination of surface structure is important as it exerts control over bed roughness, near-bed hydraulics and particle ...
Haynes, Heather, Holmes, William, Lakshmanan, Susithra, Ockleford, Anne-Marie, Vignaga, Elisa   +4 more
core  

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

TFEB/Mitf links impaired nuclear import to autophagolysosomal dysfunction in C9-ALS

eLife, 2020
Disrupted nucleocytoplasmic transport (NCT) has been implicated in neurodegenerative disease pathogenesis; however, the mechanisms by which disrupted NCT causes neurodegeneration remain unclear.
Kathleen M Cunningham, Kirstin Maulding, Kai Ruan, Mumine Senturk, Jonathan C Grima, Hyun Sung, Zhongyuan Zuo, Helen Song, Junli Gao, Sandeep Dubey, Jeffrey D Rothstein, Ke Zhang, Hugo J Bellen, Thomas E Lloyd   +13 more
doaj   +1 more source