Results 91 to 100 of about 159,475 (307)

Nuclear pore protein NUP210 depletion suppresses metastasis through heterochromatin-mediated disruption of tumor cell mechanical response

Nature Communications, 2021
The involvement of nuclear pore proteins in cellular mechanosensing and metastasis is unclear. Here the authors identify that nuclear pore protein NUP210 promotes metastasis through the interaction with mechanotransducer LINC complex protein and ...
Ruhul Amin, Anjali Shukla, Jacqueline Jufen Zhu, Sohyoung Kim, Ping Wang, Simon Zhongyuan Tian, Andy D. Tran, Debasish Paul, Steven D. Cappell, Sandra Burkett, Huaitian Liu, Maxwell P. Lee, Michael J. Kruhlak, Jennifer E. Dwyer, R. Mark Simpson, Gordon L. Hager, Yijun Ruan, Kent W. Hunter   +17 more
doaj   +1 more source

Pore structure characterization of low permeability rocks [PDF]

, 2014
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Ciência e Engenharia de Materiais, Florianópolis, 2014.Hoje as pesquisas em rochas de baixa permeabilidade (grande tendência no mundo e em breve ...
Schmitt, Mayka
core  

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Molecular genetics of oogenesis in Drosophila melanogaster [PDF]

Invertebrate Survival Journal, 2004
Gonadal development requires complex differentiation programs leading to the production of functional female and male gametes. Upon fertilization, while the male germ cell contributes to the newly formed zygote only its genetic material, the female germ ...
S Gigliotti, V Cavaliere, G Gargiulo, F Graziani, C Malva   +4 more
doaj   +1 more source

Comparative study on pore size distribution in coal based on mercury intrusion-low temperature liquid nitrogen combined pore and nuclear magnetic resonance analysis

Meikuang Anquan
The pore structure measurement in coal is commonly analyzed by mercury intrusion method, low temperature liquid nitrogen method and nuclear magnetic resonance method. Due to the different test methods, the results cannot be used uniformly, and the matrix
Nana LI, Huihu LIU, Shuxun SANG
doaj   +1 more source

TFEB/Mitf links impaired nuclear import to autophagolysosomal dysfunction in C9-ALS

eLife, 2020
Disrupted nucleocytoplasmic transport (NCT) has been implicated in neurodegenerative disease pathogenesis; however, the mechanisms by which disrupted NCT causes neurodegeneration remain unclear.
Kathleen M Cunningham, Kirstin Maulding, Kai Ruan, Mumine Senturk, Jonathan C Grima, Hyun Sung, Zhongyuan Zuo, Helen Song, Junli Gao, Sandeep Dubey, Jeffrey D Rothstein, Ke Zhang, Hugo J Bellen, Thomas E Lloyd   +13 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Mouse nuclear myosin I knock-out shows interchangeability and redundancy of myosin isoforms in the cell nucleus. [PDF]

, 2013
Nuclear myosin I (NM1) is a nuclear isoform of the well-known "cytoplasmic" Myosin 1c protein (Myo1c). Located on the 11(th) chromosome in mice, NM1 results from an alternative start of transcription of the Myo1c gene adding an extra 16 amino acids at ...
Dzijak, Rastislav, Eckhard Wolf, Oliver Eickelberg, Fuchs Helmut, Alexander Bohla, Schmidt, Volker, Rülicke, T., Hrabě de Angelis, M., Rohožková, Jana, Alžběta Kalendová, Martin Hrabě de Angelis, Schmidt Volker, Dzijak, R., Kalendová, Alžběta, Rathkolb, Birgit, Hozák, Pavel, Dzijak Rastislav, Hans, Wolfgang, Ali Önder Yildirim, Rathkolb, B., Venit, Tomáš, Wolf Eckhard, Hans Wolfgang, Yildirim Ali Önder, Fuchs, H., Hozák Pavel, Bohla Alexander, Stoeger Tobias, Gailus-Durner, Valérie, Jana Rohožková, Hrabé de Angelis, Martin, Kahle-Stephan, M., Valérie Gailus-Durner, Wolf, E., Stoeger, Tobias, Thomas Rülicke, Gailus-Durner, V., Volker Schmidt, Kahle Michal, Helmut Fuchs, Kahle, Michal, Eickelberg, O., Kalendova, A., Venit Tomáš, Eickelberg Oliver, Bohla, A., Rastislav Dzijak, Michal Kahle, Rohožková Jana, Yildirim, A.Ö., Venit, T., Eickelberg, Oliver, Stöger, T., Wolfgang Hans, Rülicke Thomas, Hans, W., Rohozkova, J., Rathkolb Birgit, Bohla, Alexander, Birgit Rathkolb, Rülicke, Thomas, Tobias Stoeger, Tomáš Venit, Fuchs, Helmut, de Angelis Martin Hrabě, Schmidt, V., Yildirim, Ali Önder, Gailus-Durner Valérie, Wolf, Eckhard, Hozak, P., Kalendová Alžběta, Pavel Hozák   +71 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source