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Metabolic transcriptional memory [PDF]

open access: yesMolecular Metabolism, 2020
Background: Organisms can be primed by metabolic exposures to continue expressing response genes even once the metabolite is no longer available, and can affect the speed and magnitude of responsive gene expression during subsequent exposures.
Poonam Bheda
doaj   +7 more sources

Establishment and inheritance of epigenetic transcriptional memory [PDF]

open access: yesFrontiers in Molecular Biosciences, 2022
For certain inducible genes, the rate and molecular mechanism of transcriptional activation depends on the prior experiences of the cell. This phenomenon, called epigenetic transcriptional memory, accelerates reactivation and requires both changes in ...
Bethany Sump, Jason Brickner
doaj   +6 more sources

Nup98-dependent transcriptional memory is established independently of transcription [PDF]

open access: yeseLife, 2022
Cellular ability to mount an enhanced transcriptional response upon repeated exposure to external cues is termed transcriptional memory, which can be maintained epigenetically through cell divisions and can depend on a nuclear pore component Nup98.
Pau Pascual-Garcia   +2 more
doaj   +5 more sources

The Mediator kinase module enhances polymerase activity to regulate transcriptional memory after heat stress in Arabidopsis [PDF]

open access: yesThe EMBO Journal
Plants are often exposed to recurring adverse environmental conditions in the wild. Acclimation to high temperatures entails transcriptional responses, which prime plants to better withstand subsequent stress events.
Tim Crawford   +8 more
doaj   +3 more sources

The elusive transcriptional memory trace. [PDF]

open access: yesOxf Open Neurosci, 2022
Abstract Memory is the brain faculty to store and remember information. It is a sequential process in which four different phases can be distinguished: encoding or learning, consolidation, storage and reactivation. Since the discovery of the first Drosophila gene essential for memory formation in 1976, our knowledge of its mechanisms has
Gil-Marti B   +5 more
europepmc   +4 more sources

Transcriptional memory of gene expression across generations participates in transgenerational plasticity of field pennycress in response to cadmium stress [PDF]

open access: yesFrontiers in Plant Science, 2022
Transgenerational plasticity (TGP) occurs when maternal environments influence the expression of traits in offspring, and in some cases may increase fitness of offspring and have evolutionary significance.
Gengyun Li   +11 more
doaj   +2 more sources

Differentiation is accompanied by a progressive loss in transcriptional memory. [PDF]

open access: yesBMC Biol, 2022
Abstract Background Cell differentiation requires the integration of two opposite processes, a stabilizing cellular memory, especially at the transcriptional scale, and a burst of gene expression variability which follows the differentiation induction.
Fourneaux C   +13 more
europepmc   +6 more sources

Genomic and epigenomic determinants of heat stress-induced transcriptional memory in Arabidopsis [PDF]

open access: yesGenome Biology, 2023
Background Transcriptional regulation is a key aspect of environmental stress responses. Heat stress induces transcriptional memory, i.e., sustained induction or enhanced re-induction of transcription, that allows plants to respond more efficiently to a ...
Christian Kappel   +6 more
doaj   +2 more sources

Transcriptional Memory in Taraxacum mongolicum in Response to Long-Term Different Grazing Intensities [PDF]

open access: yesPlants, 2022
Grazing, as an important land use method in grassland, has a significant impact on the morphological and physiological traits of plants. However, little is known about how the molecular mechanism of plant responds to different grazing intensities.
Yalin Wang   +5 more
doaj   +2 more sources

Mitotically heritable, RNA polymerase II-independent H3K4 dimethylation stimulates INO1 transcriptional memory [PDF]

open access: yeseLife, 2022
For some inducible genes, the rate and molecular mechanism of transcriptional activation depend on the prior experiences of the cell. This phenomenon, called epigenetic transcriptional memory, accelerates reactivation, and requires both changes in ...
Bethany Sump   +4 more
doaj   +2 more sources

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