Results 211 to 220 of about 326,922 (335)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Nuclear pore passage of the HIV capsid is driven by its unusual surface amino acid composition. [PDF]

Nat Struct Mol Biol
Fu L, Cheng S, Riedel D, Kopecny L, Schuh M, Görlich D.   +5 more
europepmc   +1 more source

Coarse-grained molecular dynamics simulation of transport through the nuclear pore complex

, 2014
Ali Ghavami
openalex   +1 more source

The nuclear pore protein NUP98 impedes LTR-driven basal gene expression of HIV-1, viral propagation, and infectivity [PDF]

Kumaraswami Chintala, Sriram Yandrapally, Warisha Faiz, Chhaya Rani Kispotta, Satarupa Sarkar, Krishnaveni Mishra, Sharmistha Banerjee   +6 more
openalex   +1 more source

In vivo analysis of protein crowding within the nuclear pore complex in interphase and mitosis [PDF]

, 2017
Hideaki Konishi, Suguru Asai, Tomonobu M. Watanabe, Shige H. Yoshimura   +3 more
openalex   +1 more source

Nuclear Pore Complex [PDF]

, 2020
openaire   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Direct visualization of HIV-1 core nuclear import and its interplay with the nuclear pore. [PDF]

EMBO Rep
Hou Z, Fronik S, Shen Y, Chen L, Thompson C, Neumann S, Zhang P.   +6 more
europepmc   +1 more source

Nuclear Pore Protein Meets Transcription Factor in Neural Fate [PDF]

, 2017
Taro Kitazawa, Filippo M. Rijli
openalex   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source