Results 221 to 230 of about 2,343,531 (340)

Non-classical functions of nuclear pore proteins in ciliopathy. [PDF]

Front Mol Biosci, 2023
Chen Y, Zhang Y, Zhou X.
europepmc   +1 more source

Molecular architecture of the inner ring scaffold of the human nuclear pore complex

Science, 2016
J. Kosiński, S. Mosalaganti, Alexander von Appen, Roman Teimer, Amanda L. DiGuilio, W. Wan, K. Bui, W. Hagen, J. Briggs, J. Glavy, E. Hurt, Martin Beck   +11 more
semanticscholar   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Simulating structurally variable nuclear pore complexes for microscopy. [PDF]

Bioinformatics, 2023
Theiss M, Hériché JK, Russell C, Helekal D, Soppitt A, Ries J, Ellenberg J, Brazma A, Uhlmann V.   +8 more
europepmc   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Strategies for the Viral Exploitation of Nuclear Pore Transport Pathways. [PDF]

Viruses
Zhang X, Lim K, Qiu Y, Hazawa M, Wong RW.   +4 more
europepmc   +1 more source

Nuclear pore complex and nucleocytoplasmic transport disruption in neurodegeneration. [PDF]

FEBS Lett, 2023
Cristi AC, Rapuri S, Coyne AN.
europepmc   +1 more source

Architecture of the symmetric core of the nuclear pore

Science, 2016
D. H. Lin, T. Stuwe, S. Schilbach, E. J. Rundlet, T. Perriches, G. Mobbs, Yanbin Fan, K. Thierbach, F. Huber, L. N. Collins, Andrew M. Davenport, Y. Jeon, A. Hoelz   +12 more
semanticscholar   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

Integrative spatiotemporal modeling of biomolecular processes: Application to the assembly of the nuclear pore complex. [PDF]

Proc Natl Acad Sci U S A
Latham AP, Zhang W, Tempkin JOB, Otsuka S, Ellenberg J, Sali A.   +5 more
europepmc   +1 more source