Results 231 to 240 of about 326,922 (335)

Commentary: Manifold Routes to a Nucleus

open access: yesFrontiers in Microbiology, 2019
Christian Jogler   +2 more
doaj   +1 more source

Atomic structure of the Y complex of the nuclear pore

open access: green, 2015
K. Kelley   +3 more
openalex   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

HIV-1 nuclear import is selective and depends on both capsid elasticity and nuclear pore adaptability. [PDF]

open access: yesNat Microbiol
Hou Z   +10 more
europepmc   +1 more source

Nuclear pores as versatile reference standards for quantitative superresolution microscopy

open access: green, 2019
Jervis Vermal Thevathasan   +19 more
openalex   +2 more sources

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

The Potential of Nuclear Pore Complexes in Cancer Therapy. [PDF]

open access: yesMolecules
Zaitsava H   +4 more
europepmc   +1 more source

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