Earthing effects on mitochondrial function: ATP production and ROS generation
FEBS Open Bio, EarlyView.In contrast to sham and naive controls, grounded mitochondria not only exhibit significantly enhanced energy production but also demonstrate a remarkable reduction in membrane potential and oxidative stress. This suggests a profound improvement in mitochondrial health, presenting a promising avenue for therapeutic interventions.
Cecilia Giulivi, Richard Kotz
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Homeostatic regulation of nucleoporins is a central driver of nuclear pore biogenesis. [PDF]
Cell RepSakuma S +6 more
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Interactions of Chromatin with the Nuclear Lamina and Nuclear Pore Complexes. [PDF]
Int J Mol Sci, 2023 Shevelyov YY.
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The Matrix Protein of Vesicular Stomatitis Virus Inhibits Nucleocytoplasmic Transport When It Is in the Nucleus and Associated with Nuclear Pore Complexes [PDF]
, 2000 Jeannine M. Petersen +4 more
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FEBS Open Bio, EarlyView.Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley +1 more source
HIV-1 nuclear import is selective and depends on both capsid elasticity and nuclear pore adaptability. [PDF]
Nat MicrobiolHou Z +10 more
europepmc +1 more source
Non-classical functions of nuclear pore proteins in ciliopathy. [PDF]
Front Mol Biosci, 2023 Chen Y, Zhang Y, Zhou X.
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The nuclear pore complex: mediator of translocation between nucleus and cytoplasm [PDF]
, 2000 Terence Allen +4 more
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Interaction of class III cellobiose dehydrogenase with lytic polysaccharide monooxygenase
FEBS Open Bio, EarlyView.The activity of lytic polysaccharide monooxygenase (LPMO) is supported by its auxiliary enzyme cellobiose dehydrogenase (CDH). The catalytic activity of both enzymes is coupled by electron transfer and a cyclic cascade generating substrates for both enzymes – hydrogen peroxide for LPMO and oxidized and non‐oxidized cellobiose and cello‐oligosaccharide ...
Angela Giorgianni +4 more
wiley +1 more source