Results 261 to 270 of about 2,254,561 (377)

Architecture of the symmetric core of the nuclear pore

open access: yesScience, 2016
D. H. Lin   +12 more
semanticscholar   +1 more source

The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity

open access: yesFEBS Open Bio, EarlyView.
We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda   +9 more
wiley   +1 more source

The Potential of Nuclear Pore Complexes in Cancer Therapy. [PDF]

open access: yesMolecules
Zaitsava H   +4 more
europepmc   +1 more source

Mlp2p, A Component of Nuclear Pore Attached Intranuclear Filaments, Associates with Nic96p [PDF]

open access: hybrid, 2000
Buket Kosova   +6 more
openalex   +1 more source

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

open access: yesFEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo   +11 more
wiley   +1 more source

Implications of a multiscale structure of the yeast nuclear pore complex. [PDF]

open access: yesMol Cell, 2023
Akey CW   +9 more
europepmc   +1 more source

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