Results 41 to 50 of about 2,139,515 (306)

Skin cancer biology and barriers to treatment: Recent applications of polymeric micro/nanostructures

open access: yesJournal of Advanced Research, 2022
Background: Skin cancer has been the leading type of cancer worldwide. Melanoma and non-melanoma skin cancers are now the most common types of skin cancer that have been reached to epidemic proportion.
Nazeer Hussain Khan   +8 more
doaj   +1 more source

The subnuclear localization of tRNA ligase in yeast [PDF]

open access: yes, 1987
Yeast tRNA ligase is an enzyme required for tRNA splicing. A study by indirect immune fluorescence shows that this enzyme is localized in the cell nucleus. At higher resolution, studies using indirect immune electron microscopy show this nuclear location
Abelson, John, Clark, Michael W.
core   +1 more source

Roles of Hydrogen Sulfide Donors in Common Kidney Diseases

open access: yesFrontiers in Pharmacology, 2020
Hydrogen sulfide (H2S) plays a key role in the regulation of physiological processes in mammals. The decline in H2S level has been reported in numerous renal disorders.
Ebenezeri Erasto Ngowi   +26 more
doaj   +1 more source

Tissue Engineering in Stomatology: A Review of Potential Approaches for Oral Disease Treatments

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Tissue engineering is an emerging discipline that combines engineering and life sciences. It can construct functional biological structures in vivo or in vitro to replace native tissues or organs and minimize serious shortages of donor organs during ...
Lilan Cao   +8 more
doaj   +1 more source

Androgen receptor phosphorylation status at serine 578 predicts poor outcome in prostate cancer patients [PDF]

open access: yes, 2016
Purpose: Prostate cancer growth is dependent upon androgen receptor (AR) activation, regulated via phosphorylation. Protein kinase C (PKC) is one kinase that can mediate AR phosphorylation. This study aimed to establish if AR phosphorylation by PKC is of
Edwards, J.   +7 more
core   +1 more source

The monkeypox diagnosis, treatments and prevention: A review

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
The world is currently dealing with a second viral outbreak, monkeypox, which has the potential to become an epidemic after the COVID-19 pandemic.
Saadullah Khattak   +7 more
doaj   +1 more source

Fragment-Based Approaches Identified Tecovirimat-Competitive Novel Drug Candidate for Targeting the F13 Protein of the Monkeypox Virus

open access: yesViruses, 2023
Monkeypox is a serious public health issue in tropical and subtropical areas. Antivirals that target monkeypox proteins might lead to more effective and efficient therapy. The F13 protein is essential for the growth and maturation of the monkeypox virus.
Yasir Ali   +8 more
doaj   +1 more source

Different fates of the chloroplast tufA gene following its transfer to the nucleus in green algae [PDF]

open access: yes, 1990
Previous work suggested that the tufA gene, encoding protein synthesis elongation factor Tu, was transferred from the chloroplast to the nucleus within the green algal lineage giving rise to land plants.
Baldauf, S.L.   +2 more
core   +4 more sources

The potential role of hydrogen sulfide in cancer cell apoptosis

open access: yesCell Death Discovery
For a long time, hydrogen sulfide (H2S) has been considered a toxic compound, but recent studies have found that H2S is the third gaseous signaling molecule which plays a vital role in physiological and pathological conditions.
Wei Gao   +9 more
doaj   +1 more source

Rho-Kinase Inhibitors as Emerging Targets for Glaucoma Therapy

open access: yesOphthalmology and Therapy, 2023
Glaucoma, the leading cause of irreversible blindness worldwide, is a chronic and progressive optic neuropathy characterized by damage to the optic and retinal nerve fiber layers, which can lead to permanent loss of peripheral or central vision ...
Jun Wang, Hanke Wang, Yalong Dang
doaj   +1 more source

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