Results 31 to 40 of about 2,139,515 (306)
Nuclear Polyadenylate-Binding Protein [PDF]
Molecular and Cellular Biology, 1985 Polyadenylate-binding activity can be detected in eluates from sodium dodecyl sulfate gels by a nitrocellulose filter-binding assay. Nuclear extracts from rat liver show a single peak of binding activity at 50 to 55 kilodaltons; cytoplasmic extracts show a single peak at 70 to 80 kilodaltons, corresponding to a 75-kilodalton protein previously ...
A B, Sachs, R D, Kornberg
openaire +2 more sources
Frontiers in Neurology, 2021 COVID-19 has spread rapidly worldwide since its outbreak and has now become a major public health problem. More and more evidence indicates that SARS-CoV-2 may not only affect the respiratory system but also cause great harm to the central nervous system.
Lintao Wang +12 more
doaj +1 more source
Cytochrome oxidase subunit VI of Trypanosoma brucei is imported without a cleaved presequence and is developmentally regulated at both RNA and protein levels [PDF]
, 2001 Mitochondrial respiration in the African trypanosome undergoes dramatic developmental stage regulation. This requires co-ordinated control of components encoded by both the nuclear genome and the kinetoplast, the unusual mitochondrial genome of these ...
Benne R. +29 more
core +1 more source
Biology of PEST‐Containing Nuclear Protein: A Potential Molecular Target for Cancer Research
Frontiers in Oncology, 2022 PEST-containing nuclear protein (PCNP), a novel nuclear protein, is involved in vital cellular processes like cell proliferation and mediates tumorigenesis.
Nazeer Hussain Khan +14 more
doaj +1 more source
Reversal of terminal differentiation and control of DNA replication [PDF]
, 1993 DNA replication in mammalian cells occurs in discrete nuclear foci. Here we show that terminally differentiated myotubes can be induced to reenter S phase and show the same pattern of replication foci as cycling cells.
Cardoso, M. Cristina +2 more
core +1 more source
Insight into the Double-Edged Role of Ferroptosis in Disease
Biomolecules, 2021 Ferroptosis, a newly described type of iron-dependent programmed cell death that is distinct from apoptosis, necroptosis, and other types of cell death, is involved in lipid peroxidation (LP), reactive oxygen species (ROS) production, and mitochondrial ...
Lei Zhang +7 more
doaj +1 more source
Functional Characterization of the Eukaryotic Cysteine Desulfurase Nfs1p from Saccharomyces cerevisiae [PDF]
, 2004 Previous studies have indicated that the essential protein Nfs1 performs a crucial role in cellular iron-sulfur (Fe/S) protein maturation. The protein is located predominantly in mitochondria, yet low amounts are present in cytosol and nucleus.
Balk +73 more
core +3 more sources
Hydrogen Sulfide Biology and Its Role in Cancer
Molecules, 2022 Hydrogen sulfide (H2S) is an endogenous biologically active gas produced in mammalian tissues. It plays a very critical role in many pathophysiological processes in the body.
Saadullah Khattak +11 more
doaj +1 more source
Nuclear constriction segregates mobile nuclear proteins away from chromatin [PDF]
Molecular Biology of the Cell, 2016 As a cell squeezes its nucleus through adjacent tissue, penetrates a basement membrane, or enters a small blood capillary, chromatin density and nuclear factors could in principle be physically perturbed. Here, in cancer cell migration through rigid micropores and in passive pulling into micropipettes, local compaction of chromatin is observed ...
Irianto, Jerome +7 more
openaire +2 more sources
Different domains cooperate to target the human ribosomal L7a protein to the nucleus and to the nucleoli. [PDF]
, 1997 The human ribosomal protein L7a is a component of the major ribosomal subunit. We transiently expressed in HeLa cells L7a-β-galactosidase fusion proteins and studied their subcellular localization by indirect immunofluorescence staining with anti-β ...
Giulia RUSSO +2 more
core +1 more source