Results 11 to 20 of about 2,139,515 (306)

The role of microRNAs in depression

Frontiers in Pharmacology, 2023
Major depressive disorder (MDD) is a psychiatric disorder with increasing prevalence worldwide. It is a leading cause of disability and suicide, severely affecting physical and mental health.
Ruidong Ding, Dingyuan Su, Qian Zhao, Yu Wang, Jia-Yi Wang, Shuangyu Lv, Xinying Ji, Xinying Ji, Xinying Ji   +8 more
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The Role of Hydrogen Sulfide in the Development and Progression of Lung Cancer

Molecules, 2022
Lung cancer is one of the 10 most common cancers in the world, which seriously affects the normal life and health of patients. According to the investigation report, the 3-year survival rate of patients with lung cancer is less than 20%.
Yi-Lun Yang, Ka Zhang, Ze-Tao Zhou, Zhi-Liang Jiang, Yi Liu, Yan-Xia Zhang, Zhi-Hui Liu, Xin-Ying Ji, Dong-Dong Wu   +8 more
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Protective limb remote ischemic post-conditioning against high-intraocular-pressure-induced retinal injury in mice [PDF]

International Journal of Ophthalmology, 2022
AIM: To determine whether limb remote ischemic post-conditioning (LRIC) protects against high-intraocular-pressure (IOP)-induced retinal injury, and to identify underlying molecular mechanisms.
Qi-Jiang Zhu, Lei Zhang, Shuang-Yu Lyu, Zhan-Jun Cui, En-She Jiang, Jun Wang   +5 more
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Nanomedicine: A Promising Way to Manage Alzheimer’s Disease

Frontiers in Bioengineering and Biotechnology, 2021
Alzheimer’s disease (AD) is a devastating disease of the aging population characterized by the progressive and slow brain decay due to the formation of extracellular plaques in the hippocampus.
Nazeer Hussain Khan, Maria Mir, Ebenezeri Erasto Ngowi, Ebenezeri Erasto Ngowi, Ujala Zafar, Muhammad Mahtab Aslam Khan Khakwani, Saadullah Khattak, Yuan-Kun Zhai, Yuan-Kun Zhai, En-She Jiang, En-She Jiang, Meng Zheng, Shao-Feng Duan, Shao-Feng Duan, Jian-She Wei, Jian-She Wei, Dong-Dong Wu, Dong-Dong Wu, Xin-Ying Ji, Xin-Ying Ji   +19 more
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Nanotechnology prospects in brain therapeutics concerning gene-targeting and nose-to-brain administration

iScience, 2023
Summary: Neurological diseases are one of the most pressing issues in modern times worldwide. It thus possesses explicit attention from researchers and medical health providers to guard public health against such an expanding threat.
Dong-Dong Wu, Yasmine Ahmed Salah, Ebenezeri Erasto Ngowi, Yan-Xia Zhang, Saadullah Khattak, Nazeer Hussain Khan, Yan Wang, Tao Li, Zi-Hua Guo, Yan-Mei Wang, Xin-Ying Ji   +10 more
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Hydrogen Sulfide Attenuates High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease by Inhibiting Apoptosis and Promoting Autophagy via Reactive Oxygen Species/Phosphatidylinositol 3-Kinase/AKT/Mammalian Target of Rapamycin Signaling Pathway

Frontiers in Pharmacology, 2020
Non-alcoholic fatty liver disease (NAFLD) is a common chronic liver disease worldwide. Hydrogen sulfide (H2S) is involved in a wide range of physiological and pathological processes.
Dongdong Wu, Dongdong Wu, Dongdong Wu, Peiyu Zhong, Peiyu Zhong, Yizhen Wang, Yizhen Wang, Qianqian Zhang, Qianqian Zhang, Jianmei Li, Jianmei Li, Zhengguo Liu, Zhengguo Liu, Ailing Ji, Ailing Ji, Yanzhang Li, Yanzhang Li   +16 more
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Regulation and physiological functions of phoenixin

Frontiers in Molecular Biosciences, 2022
Phoenixin is a newly discovered neuropeptide generated from small integral membrane protein 20. Phoenixin is a ligand for the G protein-coupled receptor 173 (GPR173) and has been detected in central and peripheral tissues of human, rats, mice, bovine ...
Han Liang, Qian Zhao, Shuangyu Lv, Xinying Ji   +3 more
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Regulation of NF-κB by PML and PML-RARα [PDF]

, 2017
Promyelocytic Leukemia (PML) is a nuclear protein that forms sub-nuclear structures termed nuclear bodies associated with transcriptionally active genomic regions. PML is a tumour suppressor and regulator of cell differentiation.
Ahmed, Abrar, Carmody, Ruaidhri J., Chen, Youhai H., Keeshan, Karen, Lindsay, Andrew J., McCaffrey, Mary W., Mitxitorena, Izaskun, Pandolfi, Pier Paolo, Wan, Xiaochun   +8 more
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Genome-Wide Analysis of Codon Usage Patterns of SARS-CoV-2 Virus Reveals Global Heterogeneity of COVID-19

Biomolecules, 2021
The ongoing outbreak of coronavirus disease COVID-19 is significantly implicated by global heterogeneity in the genome organization of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The causative agents of global heterogeneity in the whole
Saadullah Khattak, Mohd Ahmar Rauf, Qamar Zaman, Yasir Ali, Shabeen Fatima, Pir Muhammad, Tao Li, Hamza Ali Khan, Azhar Abbas Khan, Ebenezeri Erasto Ngowi, Dong-Dong Wu, Xin-Ying Ji   +11 more
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Nuclear protein import [PDF]

Current Opinion in Cell Biology, 1997
The defining feature of eukaryotic organisms is the cell nucleus. All nuclear proteins are synthesized in the cytoplasm and need to be imported through the nuclear pore complexes (NPCs) into the nucleus. Import can be directed by various signals, of which the classical nuclear localization signal (NLS) and the M9 import signal are the best ...
openaire   +3 more sources