Results 21 to 30 of about 6,030,389 (286)
The role of microRNAs in depression
Frontiers in Pharmacology, 2023 Major depressive disorder (MDD) is a psychiatric disorder with increasing prevalence worldwide. It is a leading cause of disability and suicide, severely affecting physical and mental health.
Ruidong Ding +8 more
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The Role of Hydrogen Sulfide in the Development and Progression of Lung Cancer
Molecules, 2022 Lung cancer is one of the 10 most common cancers in the world, which seriously affects the normal life and health of patients. According to the investigation report, the 3-year survival rate of patients with lung cancer is less than 20%.
Yi-Lun Yang +8 more
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Nanomedicine: A Promising Way to Manage Alzheimer’s Disease
Frontiers in Bioengineering and Biotechnology, 2021 Alzheimer’s disease (AD) is a devastating disease of the aging population characterized by the progressive and slow brain decay due to the formation of extracellular plaques in the hippocampus.
Nazeer Hussain Khan +19 more
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Protective limb remote ischemic post-conditioning against high-intraocular-pressure-induced retinal injury in mice [PDF]
International Journal of Ophthalmology, 2022 AIM: To determine whether limb remote ischemic post-conditioning (LRIC) protects against high-intraocular-pressure (IOP)-induced retinal injury, and to identify underlying molecular mechanisms.
Qi-Jiang Zhu +5 more
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iScience, 2023 Summary: Neurological diseases are one of the most pressing issues in modern times worldwide. It thus possesses explicit attention from researchers and medical health providers to guard public health against such an expanding threat.
Dong-Dong Wu +10 more
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Frontiers in Pharmacology, 2020 Non-alcoholic fatty liver disease (NAFLD) is a common chronic liver disease worldwide. Hydrogen sulfide (H2S) is involved in a wide range of physiological and pathological processes.
Dongdong Wu +16 more
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Regulation and physiological functions of phoenixin
Frontiers in Molecular Biosciences, 2022 Phoenixin is a newly discovered neuropeptide generated from small integral membrane protein 20. Phoenixin is a ligand for the G protein-coupled receptor 173 (GPR173) and has been detected in central and peripheral tissues of human, rats, mice, bovine ...
Han Liang +3 more
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The function of the nuclear envelope in nuclear protein accumulation. [PDF]
The Journal of cell biology, 1988 The mechanism by which proteins accumulate in the cell nucleus is not yet known. Two alternative mechanisms are discussed here: (a) selective unidirectional entry of karyophilic proteins through the nuclear pores, and (b) free diffusion of all proteins through the nuclear pores and specific binding of nuclear proteins to nondiffusible components of the
Zimmer, F., Dreyer, C., Hausen, P.
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Proteomic identification of heterogeneous nuclear ribonucleoprotein L as a novel component of SLM/Sam68 nuclear bodies [PDF]
, 2009 Background: Active pre-mRNA splicing occurs co-transcriptionally, and takes place throughout the nucleoplasm of eukaryotic cells. Splicing decisions are controlled by networks of nuclear RNA-binding proteins and their target sequences, sometimes in ...
Rajan, P. +55 more
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Protein phosphatases at the nuclear envelope [PDF]
Biochemical Society Transactions, 2018 The nuclear envelope (NE) is a unique topological structure formed by lipid membranes (Inner and Outer Membrane: IM and OM) interrupted by open channels (Nuclear Pore complexes). Besides its well-established structural role in providing a physical separation between the genome and the cytoplasm and regulating the exchanges between the two cellular ...
Raquel Sales Gil +3 more
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