Results 51 to 60 of about 8,751,128 (381)

Tissue Engineering in Stomatology: A Review of Potential Approaches for Oral Disease Treatments

Frontiers in Bioengineering and Biotechnology, 2021
Tissue engineering is an emerging discipline that combines engineering and life sciences. It can construct functional biological structures in vivo or in vitro to replace native tissues or organs and minimize serious shortages of donor organs during ...
Lilan Cao, Huiying Su, Mengying Si, Jing Xu, Xin Chang, Jiajia Lv, Jiajia Lv, Yuankun Zhai, Yuankun Zhai   +8 more
doaj   +1 more source

Interaction of eukaryotic translation initiation factor 4G with the nuclear cap-binding complex provides a link between nuclear and cytoplasmic functions of the m7 guanosine cap [PDF]

, 2001
In eukaryotes the majority of mRNAs have an m7G cap that is added cotranscriptionally and that plays an important role in many aspects of mRNA metabolism.
Afonina E., Boisvert F. M., Bushell M., Carmo-Fonseca M., Cho E. J., Dostie J., Dostie J., Ferreira J. A., Flaherty S. M., Fornerod M., Fortes P., Fortes P., Fraser C. S., Fromont-Racine M., Fu X. D., Gingras A. C., Gorlich D., Hentze M., Ho C. K., Izaurralde E., Izaurralde E., Jarmolowski A., Kataoka N., Kim C. Y., Kudo N., Le Hir H., Le Hir H., Lewis J. D., Lewis J. D., Lewis J. D., Lewis J. D., Martins L. M., McCracken S., Milligan J. F., Morley S. J., Morley S. J., Neugebauer K. M., Neugebauer K. M., Ohno M., Pettersson I., Piron M., Ponting C. P., Preiss T., Rozen F., Salditt-Georgieff M., Schaegger H., Shatkin A. J., Stade K., Visa N., Watanabe M., Zhou Z.   +50 more
core   +2 more sources

Roles of Hydrogen Sulfide Donors in Common Kidney Diseases

Frontiers in Pharmacology, 2020
Hydrogen sulfide (H2S) plays a key role in the regulation of physiological processes in mammals. The decline in H2S level has been reported in numerous renal disorders.
Ebenezeri Erasto Ngowi, Ebenezeri Erasto Ngowi, Ebenezeri Erasto Ngowi, Muhammad Sarfraz, Muhammad Sarfraz, Muhammad Sarfraz, Muhammad Sarfraz, Attia Afzal, Attia Afzal, Attia Afzal, Nazeer Hussain Khan, Nazeer Hussain Khan, Saadullah Khattak, Saadullah Khattak, Xin Zhang, Xin Zhang, Tao Li, Tao Li, Shao-Feng Duan, Shao-Feng Duan, Shao-Feng Duan, Xin-Ying Ji, Xin-Ying Ji, Xin-Ying Ji, Dong-Dong Wu, Dong-Dong Wu, Dong-Dong Wu   +26 more
doaj   +1 more source

The monkeypox diagnosis, treatments and prevention: A review

Frontiers in Cellular and Infection Microbiology, 2023
The world is currently dealing with a second viral outbreak, monkeypox, which has the potential to become an epidemic after the COVID-19 pandemic.
Saadullah Khattak, Mohd Ahmar Rauf, Yasir Ali, Muhammad Tufail Yousaf, Zhihui Liu, Dong-Dong Wu, Dong-Dong Wu, Xin-Ying Ji   +7 more
doaj   +1 more source

Tumor Protein 53-Induced Nuclear Protein 1 Enhances p53 Function and Represses Tumorigenesis

Frontiers in Genetics, 2013
Tumor protein 53-induced nuclear protein 1 (TP53INP1) is a stress-induced p53-target gene whose expression is modulated by transcription factors such as p53, p73, and E2F1. TP53INP1 gene encodes two isoforms of TP53INP1 proteins, TP53INP1α and TP53INP1β,
J. Shahbazi, R. Lock, Tao Liu
semanticscholar   +1 more source

Functional Characterization of the Eukaryotic Cysteine Desulfurase Nfs1p from Saccharomyces cerevisiae [PDF]

, 2004
Previous studies have indicated that the essential protein Nfs1 performs a crucial role in cellular iron-sulfur (Fe/S) protein maturation. The protein is located predominantly in mitochondria, yet low amounts are present in cytosol and nucleus.
Balk, Balk, Cupp-Vickery, Diekert, Dutkiewicz, Floss, Frazzon, Frazzon, Garland, Gerber, Gerber, Gietz, Gyula Kispal, Harlow, Hoff, Janneke Balk, Jaschkowitz, Jens T. Kaiser, Kaiser, Kambampati, Kambampati, Katalin Sipos, Kaut, Kim, Kispal, Knight, Knight, Knox, Kolman, Land, Lange, Lange, Lauhon, Leibrecht, Leipuviene, Li, Lill, Matthies, Meyer, Mihara, Mühlenhoff, Mühlenhoff, Mühlenhoff, Nachin, Nadine Richhardt, Nakai, Nakai, Nett, Nilsson, Outten, Papenbrock, Pierrel, Roland Lill, Roy, Sambrook, Schilke, Schwartz, Sherman, Silberg, Sipos, Skovran, Stein, Strain, Takahashi, Tong, Tong, Ulrich Mühlenhoff, Ungermann, Voisine, Wang, Yuvaniyama, Zheng, Zheng, Zheng   +73 more
core   +3 more sources

Localized inhibition of protein phosphatase 1 by NUAK1 promotes spliceosome activity and reveals a MYC-sensitive feedback control of transcription. [PDF]

, 2020
Deregulated expression of MYC induces a dependence on the NUAK1 kinase, but the molecular mechanisms underlying this dependence have not been fully clarified.
Ade, C.P., Baluapuri, A., Chang, Y.C., Cossa, G., Eilers, M., Girard, C., Kempa, S., Kumar, A., Kuster, B., Lührmann, R., Mastrobuoni, G., Mumberg, D., Prinz, F., Roeschert, I., Schülein-Völk, C., Silveira Vidal, R., Walz, S., Wolf, E., Wortmann, L.   +18 more
core   +1 more source

Fragment-Based Approaches Identified Tecovirimat-Competitive Novel Drug Candidate for Targeting the F13 Protein of the Monkeypox Virus

Viruses, 2023
Monkeypox is a serious public health issue in tropical and subtropical areas. Antivirals that target monkeypox proteins might lead to more effective and efficient therapy. The F13 protein is essential for the growth and maturation of the monkeypox virus.
Yasir Ali, Hina Imtiaz, Muhammad Mutaal Tahir, Fouzia Gul, Umair Ali Khan Saddozai, Ashfaq ur Rehman, Zhi-Guang Ren, Saadullah Khattak, Xin-Ying Ji   +8 more
doaj   +1 more source

CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription.

Genes & Development, 1992
We report on the identification of a nuclear protein that serves as a dominant-negative inhibitor of the transcription factors C/EBP and LAP. A 32P-labeled LAP DNA-binding and dimerization domain "zipper probe" was used to isolate a clone that encodes a ...
D. Ron, J. Habener
semanticscholar   +1 more source

In vitro transport of a fluorescent nuclear protein and exclusion of non-nuclear proteins. [PDF]

The Journal of cell biology, 1986
An in vitro system was developed that provides a quick microscopic assay for nuclear transport. The assay uses an extract of Xenopus eggs, normal or synthetic nuclei, and a fluorescently labeled nuclear protein, nucleoplasmin. This in vitro system accurately mimics in vivo nuclear transport, both in exclusivity and in the amount of accumulation ...
Donald D. Newmeyer, Douglass J. Forbes, Deborah R. Finlay   +2 more
openaire   +3 more sources