Proteins of the Poly(ADP-Ribose) Polymerase (PARP) family modify target proteins by covalent attachment of ADP-ribose moieties onto amino acid side chains.
Chao Chen +3 more
doaj +1 more source
Atomic-scale imaging of a 27-nuclear-spin cluster using a single-spin quantum sensor
Nuclear magnetic resonance (NMR) is a powerful method for determining the structure of molecules and proteins. While conventional NMR requires averaging over large ensembles, recent progress with single-spin quantum sensors has created the prospect of ...
Abobeih, M. H. +8 more
core +1 more source
In situ isolation of nuclei or nuclear proteins from adherent cells: a simple, effective method with less cytoplasmic contamination. [PDF]
Qin Y +6 more
europepmc +1 more source
PAR-dependent and geometry-dependent mechanisms of spindle positioning. [PDF]
During intrinsically asymmetric division, the spindle is oriented onto a polarized axis specified by a group of conserved PAR proteins. Extrinsic geometric asymmetry generated by cell shape also affects spindle orientation in some systems, but how ...
Hayashi, Adam +3 more
core
B-cell chronic lymphocytic leukemia-associated nuclear antigens [PDF]
One- and two-dimensional polyacrylamide gel electrophoresis were used to compare the composition of nuclear polypeptides from normal and В-cell chronic lymphocytic leukemia mononuclear cells.
Błoński, Jerzy Z. +3 more
core
Cathepsin L inhibition prevents the cleavage of multiple nuclear proteins upon lysis of quiescent human cells. [PDF]
Gaikwad P, Kemp MG.
europepmc +1 more source
Weaving a pattern from disparate threads: lamin function in nuclear assembly and DNA replication [PDF]
The major residual structure that remains associated with the nuclear envelope following extraction of isolated nuclei or oocyte germinal vesicles with non-ionic detergents, nucleases and high salt is the lamina (Fawcett, 1966; Aaronson and Blobel ...
Bridger, JM +3 more
core
Joint single-cell measurements of nuclear proteins and RNA in vivo. [PDF]
Chung H +9 more
europepmc +1 more source
ARHI (DIRAS 3), an Imprinted Tumor Suppressor Gene, Binds to Importins, and Blocks Nuclear Translocation of Stat3 [PDF]
ARHI (DIRAS3) is an imprinted tumor suppressor gene whose expression is lost in the majority of breast and ovarian cancers. Unlike its homologs Ras and Rap, ARHI functions as a tumor suppressor.
In Soon Chang +11 more
core +1 more source
Combining affinity purification and mass spectrometry to define the network of the nuclear proteins interacting with the N-terminal region of FMRP. [PDF]
Kieffer F +9 more
europepmc +1 more source

