Results 11 to 20 of about 12,222,224 (337)

Identification of Plasmodium falciparum nuclear proteins by mass spectrometry and proposed protein annotation. [PDF]

open access: yesPLoS ONE, 2018
The nuclear proteome of Plasmodium falciparum results from the continual shuttle of proteins between the cell cytoplasm-nucleus and vice versa. Using shotgun proteomics tools, we explored the nuclear proteins of mixed populations of Plasmodium falciparum
Sylvie Briquet   +6 more
doaj   +2 more sources

Both emerin and lamin C depend on lamin A for localization at the nuclear envelope [PDF]

open access: yes, 2001
Physical interactions between lamins and emerin were investigated by co-immunoprecipitation of in vitro translated proteins. Emerin interacted with in vitro translated lamins A, B1 and C in co-immunprecipitation reactions.
Whitfield, WGF   +8 more
core   +5 more sources

Removal of nonspecific binding proteins is required in co-immunoprecipitation with nuclear proteins

open access: yesBioTechniques, 2022
Whether protein samples should be pretreated to remove nonspecific binding proteins in co-immunoprecipitation (CO-IP) is controversial. In this work, nonspecific binding of proteins to agarose beads was found to be greater than that to magnetic beads ...
Xi Zeng   +8 more
doaj   +1 more source

Biology of PEST‐Containing Nuclear Protein: A Potential Molecular Target for Cancer Research

open access: yesFrontiers in Oncology, 2022
PEST-containing nuclear protein (PCNP), a novel nuclear protein, is involved in vital cellular processes like cell proliferation and mediates tumorigenesis.
Nazeer Hussain Khan   +14 more
doaj   +1 more source

Proteomic Analysis of Generative and Vegetative Nuclei Reveals Molecular Characteristics of Pollen Cell Differentiation in Lily

open access: yesFrontiers in Plant Science, 2021
In plants, the cell fates of a vegetative cell (VC) and generative cell (GC) are determined after the asymmetric division of the haploid microspore. The VC exits the cell cycle and grows a pollen tube, while the GC undergoes further mitosis to produce ...
Chen You   +10 more
doaj   +1 more source

Generation of one control and four iPSCs clones from patients with Emery-Dreifuss muscular dystrophy type 1

open access: yesStem Cell Research, 2021
Emery-Dreifuss muscular dystrophy type 1 (EDMD1) is a rare genetic disease caused by mutations in the EMD gene coding for a nuclear envelope protein emerin.
Magdalena Machowska   +4 more
doaj   +1 more source

Laminopathies: what can humans learn from fruit flies

open access: yesCellular & Molecular Biology Letters, 2018
Lamin proteins are type V intermediate filament proteins (IFs) located inside the cell nucleus. They are evolutionarily conserved and have similar domain organization and properties to cytoplasmic IFs. Lamins provide a skeletal network for chromatin, the
Marta Pałka   +6 more
doaj   +1 more source

Neofunctionalization of ciliary BBS proteins to nuclear roles is likely a frequent innovation across eukaryotes

open access: yesiScience, 2023
Summary: The eukaryotic BBSome is a transport complex within cilia and assembled by chaperonin-like BBS proteins. Recent work indicates nuclear functions for BBS proteins in mammals, but it is unclear how common these are in extant proteins or when they ...
Alexander Ewerling   +3 more
doaj   +1 more source

The function of the nuclear envelope in nuclear protein accumulation. [PDF]

open access: yesThe Journal of cell biology, 1988
The mechanism by which proteins accumulate in the cell nucleus is not yet known. Two alternative mechanisms are discussed here: (a) selective unidirectional entry of karyophilic proteins through the nuclear pores, and (b) free diffusion of all proteins through the nuclear pores and specific binding of nuclear proteins to nondiffusible components of the
Zimmer, F., Dreyer, C., Hausen, P.
openaire   +3 more sources

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