Results 221 to 230 of about 1,109,521 (262)

Identification of a nuclear protein matrix

Biochemical and Biophysical Research Communications, 1974
Abstract The structural framework of the rat liver nucleus has been identified and consists of a nuclear protein matrix. This matrix is 98.4% protein, 0.1% DNA, 1.2% RNA, and 0.5% phospholipid. The nuclear protein matrix is composed primarily of three acidic polypeptide fractions in the molecular weight range of 60–70,000 daltons.
R, Berezney, D S, Coffey
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Nuclear basic proteins in spermiogenesis

Biochimie, 1998
In animal species, spermiogenesis, the late stage of spermatogenesis, is characterized by a dramatic remodelling of chromatin which involves morphological changes and various modifications in the nature of the nuclear basic proteins. According to the evolution of species, three situations can be observed: a) persistence of somatic histones or ...
D, Wouters-Tyrou, A, Martinage, P, Chevaillier, P, Sautière   +3 more
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An inhibitor protein of nuclear protein kinases

Nature, 1979
THE cyclical phosphorylation and dephosphorylation of proteins, catalysed by protein kinases and phosphoprotein phosphatases, respectively, are important ways in which cells regulate many of their metabolic activities. Cells seem to have at least two distinct phosphorylation systems, one in the cytoplasm, the other in the nucleus.
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Studies of the nuclear residual proteins

Archives of Biochemistry and Biophysics, 1968
Abstract The nuclear residual proteins of rat liver have been prepared by solubilization with sodium deoxycholate and Sephadex gel filtration. These proteins were examined by analytical ultracentrifugation, DEAE-cellulose chromatography, starch gel electrophoresis, amino acid composition, and alkali-labile phosphorus analysis.
G, Patel, V, Patel, T Y, Wang, C R, Zobel   +3 more
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Characterization of a Sperm Nuclear Protein

American Journal of Reproductive Immunology, 1996
PROBLEM: The molecular identity of sperm DNA‐binding structural proteins contributing to the integrity of a sperm residual high salt/nuclease resistant nuclear structure is studied by cDNA cloning and monoclonal antibodies to the recombinant polypeptide.
I N, Batova, M G, Petrov, S D, Kyurkchiev, I R, Kehayov   +3 more
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Nuclear Protein Transport Pathways

Nephron Experimental Nephrology, 1999
Nuclear proteins like transcription factors and ribosomal proteins are synthesized in the cytoplasm and have to be transported into the nucleus to fulfill their functions. The transport of proteins >20–60 kD through the nuclear pore complex (NPC) into the nucleus is an active, energy-requiring process.
M, Köhler, H, Haller, E, Hartmann
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Nuclear protein tyrosine kinases

Trends in Biochemical Sciences, 1994
Protein tyrosine phosphorylation plays an important role in the transduction of extracellular signals. The prototypical protein tyrosine kinases are localized at the plasma membrane and are coupled to receptors that bind extracellular factors. Thus, protein tyrosine phosphorylation was previously thought to occur only in the cytoplasm. However, several
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Nuclear Proteins of Neoplastic Cells

1964
Publisher Summary Proteins and enzymes of the nucleus are important for the synthetic reactions involved in neoplastic cells and to the aberrations of growth that characterize these cells. It has been difficult to isolate and purify the proteins of the nucleus but in recent years, the enzymatic activities of some of these proteins have been ...
H, BUSCH, W J, STEELE
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Nuclear Pore Complex Proteins

1996
The nuclear envelope forms the boundary between the nucleus and the cytoplasm and as such regulates the exchange of macromolecules between the two compartments. The channels through the nuclear envelop that actually mediate this macromolecular traffic are the nuclear pore complexes.
R, Bastos, N, Panté, B, Burke
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Protein dynamics in the nuclear compartment

Current Opinion in Genetics & Development, 2002
The classic view of a transcriptional initiation complex is that of an assembly of factors with many protein-protein contacts, leading to a multi-component complex whose existence is a result of the stabilizing influence of the many intermolecular interactions.
Gordon L, Hager, Cem, Elbi, Matthias, Becker   +2 more
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