Results 181 to 190 of about 1,210,728 (258)

Nuclear receptor 4A1 ameliorates UUO-induced renal fibrosis by inhibiting the PI3K/AKT pathway. [PDF]

Sci Rep
Wang H, Wei Z, Xu C, Fang F, Wang Z, Zhong Y, Wang X.   +6 more
europepmc   +1 more source

Murine Models and Human Cell Line Models to Study Altered Dynamics of Ovarian Follicles in Polycystic Ovary Syndrome

Advanced Biology, EarlyView.
The manuscript examines preclinical murine and human models to study polycystic ovary syndrome (PCOS), delving into the cellular and molecular mechanisms underlying altered ovarian follicular dynamics. It explores the cellular interactions involved in normal and PCOS ovaries and outlines the current and novel strategies in the search for preclinical ...
Arturo Bevilacqua, Cristiano Giuliani, Giovanna Di Emidio, Samuel H Myers, Vittorio Unfer, Carla Tatone   +5 more
wiley   +1 more source

The Innovative Role of Nuclear Receptor Interaction Protein in Orchestrating Invadosome Formation for Myoblast Fusion. [PDF]

J Cachexia Sarcopenia Muscle
Chen HH, Lin CY, Han YJ, Huang YH, Liu YH, Hsu WE, Tsai LK, Lai HJ, Tsao YP, Huang HP, Chen SL.   +10 more
europepmc   +1 more source

Novel Biologically Active Glass Fiber Functionalized Using Magnesium Phosphate Cement Promotes Bone and Vascular Regeneration

Advanced Biology, EarlyView.
In this study, a new type of bioactive glass fiber ‐based composite magnesium phosphate bone cement is prepared and verified that its mechanical strength and biological properties. In addition, the cement may have played a biologically active role in the Notch and HIF signaling pathways.
Yuzheng Lu, Yanbo Shan, Yingjie Xiong, Jianting Ye, Yanbin Wu, Jipeng Song, Yao Zhang, Wancheng Lin, Haoye Meng, Wenjing Xu, Jiang Peng, Qiang Lu, Lixiang Ding   +12 more
wiley   +1 more source

Combining graph neural networks and transformers for few-shot nuclear receptor binding activity prediction. [PDF]

J Cheminform
Torres LHM, Arrais JP, Ribeiro B.
europepmc   +1 more source

The Regulation of Trace Metal Elements in Cancer Ferroptosis

Advanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang, Yuanyuan Xue, Lei Chang, Xuena Zhu, Wenjun Liu, Tingbo Liang   +5 more
wiley   +1 more source

Nuclear receptor E75/NR1D2 promotes tumor malignant transformation by integrating Hippo and Notch pathways. [PDF]

EMBO J
Wang X, Guo Y, Lin P, Yu M, Song S, Xu W, Kong D, Wang Y, Zhang Y, Lu F, Xie Q, Ma X.   +11 more
europepmc   +1 more source

Mechanochemical Synthesis and Characterization of Nanostructured ErB4 and NdB4 Rare‐Earth Tetraborides

Advanced Engineering Materials, Volume 27, Issue 6, March 2025.
ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur, Faruk Kaya, Bora Derin, Mustafa Lütfi Öveçoğlu, Ju Li, Duygu Ağaoğulları   +5 more
wiley   +1 more source

The orphan nuclear receptor Nr4a1 contributes to interstitial cardiac fibrosis via modulation of cardiac fibroblast and macrophage phenotype. [PDF]

Cell Mol Life Sci
Widiapradja A, Connery H, Bullock M, Kasparian AO, Clifton-Bligh R, Levick SP.   +5 more
europepmc   +1 more source

Icephobic Gradient Polymer Coatings Coupled with Electromechanical De‐icing Systems: A Promising Ice Repellent Hybrid System

Advanced Engineering Materials, EarlyView.
A hybrid system for de‐icing made of gradient polymer coatings, deposited on aluminum coupled with an electromechanical system, is demonstrated as an effective and durable strategy for reducing drastically ice adhesion. The system is capable of detaching ice blocks over the coating in less than 1 s, regardless of the ice type and covered area ...
Gabriel Hernández Rodríguez, Giulia Gastaldo, Luca Stendardo, Younes Rafik, Jason Pothin, Marc Budinger, Carlo Antonini, Valérie Pommier‐Budinger, Anna Maria Coclite   +8 more
wiley   +1 more source