Results 161 to 170 of about 36,876 (225)

Engineering of functional auditory neurons from human induced pluripotent stem cells. [PDF]

Mil Med Res
Jeong M, Vattino LG, Djurisic M, Rose KP, Hyakusoku H, Spasic S, Ma XJ, Mohri H, Hertzano R, Takesian AE, Stankovic KM.   +10 more
europepmc   +1 more source

Neotropical Snakes Reveal Different Geological Times for Dispersal Corridors Between Amazon and Atlantic Forests

Zoologica Scripta, EarlyView.
ABSTRACT Three forested dispersal corridors have been proposed within the diagonal of open/dry landscapes in South America and the relative importance of each one has been the subject of debate for forest organisms. We analysed the biogeographical history of three snake genera (Bothrops, Philodryas, and Micrurus) from different families (Viperidae ...
Matheus Pontes‐Nogueira, Tiago F. Carrijo, Ricardo J. Sawaya   +2 more
wiley   +1 more source

Citrate reduced gold nanoparticles lowered lipid content in differentiated 3T3-L1 adipocytes by altering the expression of adipogenic genes. [PDF]

Discov Nano
Hyera A, Sharma JR, Fadaka AO, Gabuza KB, Mganto-Khuselo Z, Madiehe AM, Meyer M, Sibuyi NRS.   +7 more
europepmc   +1 more source

Acute exercise‐induced lipolysis and increase in levels of fatty acid esters of hydroxy fatty acids in adipose tissue are impaired in obese and aged mice

Experimental Physiology, EarlyView.
Abstract Improving adipose tissue (AT) metabolism through exercise might increase production of lipokines from the fatty acid esters of hydroxy fatty acids (FAHFA) family. Although exercise training can increase insulin sensitivity and levels of specific FAHFA in AT and the circulation in humans, the effects of acute exercise on FAHFA levels remain ...
Marko Mitrovic, Olga Horakova, Martin Riecan, Veronika Kleinova, Tomas Cajka, Lenka Rossmeislova, Ondrej Kuda, Martin Rossmeisl   +7 more
wiley   +1 more source

Regulation of the amh gene promoter activity by SF-1 in sex-reversing Cheilinus undulatus and its adaptive evolution. [PDF]

BMC Genomics
Bu S, Zhu Y, Ji X, Zhang W, Hu C, Wen X, Luo J.   +6 more
europepmc   +1 more source

Computational modelling of cardiac fibroblast signalling reveals a key role for Ca2+ in driving atrial fibrillation‐associated fibrosis

The Journal of Physiology, EarlyView.
Abstract figure legend A pre‐existing fibroblast signalling model was enhanced by integrating atrial‐specific components and reactions linked to atrial fibrosis and atrial fibrillation (AF). The analysis highlights the central role of Ca2⁺ signalling in driving profibrotic responses to AF‐relevant stimuli, angiotensin‐II and transforming growth factor ...
Najme Khorasani, Haibo Ni, Jeffrey J Saucerman, Dobromir Dobrev, Stefano Morotti, Eleonora Grandi   +5 more
wiley   +1 more source

Pharmacogenomics of treatment toxicities in pediatric B-Cell ALL: toward safer precision therapy. [PDF]

Front Pharmacol
Lameri M, Kamergi T, Brahim A, Abdallah I, Mezzi N, Zerei S, Benkahla A, Chaabane M, Drira C, Felfel H, Ben Abdennebi Y, Khrouf MR, Amor D, Romdhane L, Chaker H.   +14 more
europepmc   +1 more source

NSAID ingestion augments training‐induced muscle hypertrophy and differentially affects muscle mRNA expression, but not strength gains, in trained men

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the impact of NSAID ingestion on resistance exercise training‐induced changes in muscle morphology, function and gene networks relative to placebo ingestion in trained males. Abstract Non‐steroidal anti‐inflammatory drugs (NSAIDs) are widely overused in sports.
Joanne E. Mallinson, Tariq Taylor, Dumitru Constantin‐Teodosiu, Despina Constantin, Martino V. Franchi, Dorothee Auer, Paul L. Greenhaff   +6 more
wiley   +1 more source

Naringin Mitigates PEDV-Induced Intestinal Damage in Suckling Piglets by Modulating Inflammatory, Antiviral, and Metabolic and Transport Pathways. [PDF]

Biomolecules
Zhang Y, Li M, Li Z, Li Z, Wang L, Zhao D, Wu T, Yi D, Hou Y.   +8 more
europepmc   +1 more source

Physiological and anatomical determinants of placental drug transfer

The Journal of Physiology, EarlyView.
Abstract figure legend Fetal exposure to pharmaceuticals and their subsequent clearance back to the maternal circulation are governed by placental transfer. Passive diffusion down a maternal‐to‐fetal concentration gradient is the primary route of fetal drug exposure, with specific compounds undergoing transporter‐mediated transfer.
Rohan M. Lewis, Anandita Umapathy, Jane K. Cleal, Bram G. Sengers   +3 more
wiley   +1 more source