Results 251 to 260 of about 548,108 (301)

Investigation on regulation of N-acetyltransferase 2 expression by nuclear receptors in human hepatocytes. [PDF]

Front Pharmacol
Hong KU, Aureliano AP, Walls KM, Hein DW.   +3 more
europepmc   +1 more source

Impact of Persistent Endocrine-Disrupting Chemicals on Human Nuclear Receptors: Insights from In Silico and Experimental Characterization. [PDF]

Int J Mol Sci
Ganesh H, Moran J, Roy S, Mathew J, Ackah-Blay J, Costello E, Shan P, Dakshanamurthy S.   +7 more
europepmc   +1 more source

A pan-family screen of nuclear receptors in immunocytes reveals ligand-dependent inflammasome control. [PDF]

Immunity
Wang Y, Zhang Y, Kim K, Han J, Okin D, Jiang Z, Yang L, Subramaniam A, Means TK, Nestlé FO, Fitzgerald KA, Randolph GJ, Lesser CF, Kagan JC, Mathis D, Benoist C.   +15 more
europepmc   +1 more source

Epigenetic regulation of nuclear receptors: Implications for endocrine-related diseases and therapeutic strategies. [PDF]

Genes Dis
Song Y, Zhang K, Zhang J, Li Q, Huang N, Ma Y, Hou N, Han F, Kan C, Sun X.   +9 more
europepmc   +1 more source

The endocannabinoid anandamide mediates anti-inflammatory effects through activation of NR4A nuclear receptors. [PDF]

Br J Pharmacol
Teichmann T, Pflüger-Müller B, Giménez VMM, Sailer F, Dirks H, Zehr S, Warwick T, Brettner F, Munoz-Tello P, Zimmer A, Tegeder I, Thomas D, Gurke R, Günther S, Heering J, Proschak E, Geisslinger G, Bibli IS, Heringdorf DMZ, Manucha W, Windbergs M, Knapp S, Weigert A, Leisegang MS, Kojetin D, Brandes RP.   +25 more
europepmc   +1 more source

Peroxisome Proliferator-Activated Receptor Family of Lipid-Activated Nuclear Receptors Alpha Silencing Promotes Oxidative Stress and Hypertrophic Phenotype in Rat Cardiac Cells. [PDF]

Antioxidants (Basel)
Bianchi M, Panera N, Petrillo S, Cicolani N, De Stefanis C, Scarsella M, Ciavardelli D, Piemonte F, Alisi A, Pastore A.   +9 more
europepmc   +1 more source

Nuclear Receptors in Energy Metabolism

, 2022
Nuclear receptors are master regulators of energy metabolism through the conversion of extracellular signals into gene expression signatures. The function of the respective nuclear receptor is tissue specific, signal and co-factor dependent. While normal nuclear receptor function is central to metabolic physiology, aberrant nuclear receptor signaling ...
Walth-Hummel, A.A., Herzig, S., Rohm, M.
openaire   +4 more sources

Nuclear Receptors in Liver Disease Δ

Hepatology, 2011
Abstract Nuclear receptors are ligand-activated transcriptional regulators of several key aspects of hepatic physiology and pathophysiology. As such, nuclear receptors control a large variety of metabolic processes including hepatic lipid metabolism, drug disposition, bile acid homeostasis, as ...
Wagner, MartinZollner, GernotTrauner, Michael   +3 more
openaire   +4 more sources

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Oxysterols and nuclear receptors

Molecular and Cellular Endocrinology, 2019
Oxysterols are derivatives of cholesterol and an important regulator of cholesterol metabolism, in part due to their role as ligands for nuclear receptors, such as the liver X receptors. Oxysterols are also known to be ligands for the RAR-related orphan receptors, involved in normal T cell differentiation.
Liqian Ma, Erik R. Nelson
openaire   +2 more sources