Production and transport of hadrons generated in nuclear cascades initiated by muons in the rock (exclusive approach) [PDF]
A. V. Dementyev+3 more
openalex +1 more source
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo+11 more
wiley +1 more source
Function of the Nuclear Transport Machinery in Maintaining the Distinctive Compositions of the Nucleus and Cytoplasm. [PDF]
Stewart M.
europepmc +1 more source
Two‐way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3
PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Reina Ueno+12 more
wiley +1 more source
Nuclear Transport of Respiratory Syncytial Virus Matrix Protein Is Regulated by Dual Phosphorylation Sites. [PDF]
Ghildyal R+6 more
europepmc +1 more source
Plasticity of an Ultrafast Interaction between Nucleoporins and Nuclear Transport Receptors
Sigrid Milles+11 more
semanticscholar +1 more source
Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu+12 more
wiley +1 more source
Cytoplasmic retention of dengue virus capsid protein by metformin impairing nuclear transport. [PDF]
Puello-Nakayama IC+5 more
europepmc +1 more source
Measuring and Interpreting Nuclear Transport in Neurodegenerative Disease-The Example of C9orf72 ALS. [PDF]
Semmelink MFW, Steen A, Veenhoff LM.
europepmc +1 more source