Results 211 to 220 of about 3,917,591 (294)

Examples for nuclear innovation – part 2: transportable and mobile heat pipe cooled microreactors

Andreas Schaffrath, Jörg Starflinger
openalex   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

Cytoplasmic retention of dengue virus capsid protein by metformin impairing nuclear transport. [PDF]

J Gen Virol
Puello-Nakayama IC, Hernandez-Castillo J, Castillo JM, Talamás-Lara D, Palacios-Rápalo SN, Del Ángel RM.   +5 more
europepmc   +1 more source

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

FEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto, Shiori Sakai, Minori Endo, Terigele, Mizuho Niibori, Taiki Morita, Yu Goto, Arisa Yoshida, Tomohiro Tanaka, Ning Lin, Takahiro Kuchimaru, Hiroyuki Nakamura, Masahiro Inoue, Shinae Kizaka‐Kondoh, Tetsuya Kadonosono   +14 more
wiley   +1 more source

NEAT1 regulates BMSCs aging through disruption of FGF2 nuclear transport. [PDF]

Stem Cell Res Ther
Wang Z, Zhen W, Wang Q, Sun Y, Jin S, Yu S, Wu X, Zhang W, Zhang Y, Xu F, Wang R, Xie Y, Sun W, Xu J, Zhang H.   +14 more
europepmc   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Schizophrenia-related Xpo7 haploinsufficiency leads to behavioral and nuclear transport pathologies. [PDF]

EMBO Rep
Toyoda S, Kikuchi M, Abe Y, Tashiro K, Handa T, Katayama S, Motokawa Y, Tanaka KF, Takahashi H, Shiwaku H.   +9 more
europepmc   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Advances and transgressions of nuclear transport checkpoint inhibitors. [PDF]

Mol Ther
Hawiger J.
europepmc   +1 more source

Environmental neurotoxicant-induced mitochondrial dysfunction impairs the nuclear pore complex and nucleocytoplasmic transport in Parkinson’s disease pathogenesis

Zainab Riaz, Yuan-Teng Chang, Ahyoung Jang, Gabriel S. Richardson, Manikandan Samidurai, Gary D. Zenitsky, Huajun Jin, Vellareddy Anantharam, Arthi Kanthasamy, Anumantha G. Kanthasamy, Anumantha G. Kanthasamy, Anumantha G. Kanthasamy   +11 more
openalex   +1 more source