Results 191 to 200 of about 3,917,591 (294)

Engineering an orthogonal ubiquitin transfer cascade with RING E3 RNF38 by phage display to reveal its regulation of nuclear transport. [PDF]

J Biol Chem
Zhou L, Jeong IH, Li H, Rios N, Zhang J, Wang X, Liu S, Xie Y, Wei W, Jeong GH, Duong D, Seyfried NT, Xue B, Shi H, Mabb AM, Wang Y, Kiyokawa H, Yin J.   +17 more
europepmc   +1 more source

Structural convergence endows nuclear transport receptor Kap114p with a transcriptional repressor function toward TATA-binding protein. [PDF]

Nat Commun, 2023
Liao CC, Wang YS, Pi WC, Wang CH, Wu YM, Chen WY, Hsia KC.   +6 more
europepmc   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Breaking barriers: Respiratory viral strategies targeting the host's nuclear pore complex and nuclear transport pathways. [PDF]

Mol Biol Cell
Udi Y, Aitchison JD, Rout MP, Obado S.
europepmc   +1 more source

Estimate unfavorable meteorological conditions based on ERA5 data for the transport of radionuclides from the nuclear power plant site

Andrzej A. Wyszogrodzki, Sławomir Potempski, Piotr Kopka, Michał Jędrzejczyk, Andrzej Mazur   +4 more
openalex   +1 more source

The structural basis of RanGAP1 regulation and catalysis in nuclear transport [PDF]

Liang Xu, Hyunbum Jang, Ruth Nussinov
openalex   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

The Biophysical Basis for Karyopherin-Dependent Ebola Virus VP24 Nuclear Transport. [PDF]

Viruses
Zhao J, Zhang B, Vogel O, Walker BW, Ma LW, Wagner ND, Basler CF, Leung DW, Gross ML, Amarasinghe GK.   +9 more
europepmc   +1 more source

Vibrational instabilities in charge transport through molecular nanojunctions: The role of anharmonic nuclear potentials

Anonymous, Michael Thoss, Samuel L. Rudge   +2 more
openalex   +1 more source

Threonine 348 regulates the subcellular localization of PTEN

FEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source