Results 11 to 20 of about 781,538 (317)
Nature Communications, 2022 Neutral networks, which are sets of genotypes connected via single mutations that share the same phenotype, are important for evolvability. Here, the authors provide experimental evidence of a neutral network in an RNA enzyme using a high-throughput ...
Rachapun Rotrattanadumrong +1 more
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Clinical Microbiology Reviews, 1995 The use of nucleic acid-based vaccines is a novel approach to immunization that elicits immune responses similar to those induced by live, attenuated vaccines. Administration of nucleic acid vaccines results in the endogenous generation of viral proteins with native conformation, glycosylation profiles, and other posttranslational modifications that ...
F R, Vogel, N, Sarver
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A novel splice variant of the human MSTN gene encodes a myostatin‐specific myostatin inhibitor
Journal of Cachexia, Sarcopenia and Muscle, 2023 Background Myostatin, encoded by the MSTN gene comprising 3 exons, is a potent negative regulator of skeletal muscle growth. Although a variety of myostatin inhibitors have been invented for increasing muscle mass in muscle wasting diseases, no effective
Kazuhiro Maeta +3 more
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eLife, 2014 Cytidine deaminases are single stranded DNA mutators diversifying antibodies and restricting viral infection. Improper access to the genome leads to translocations and mutations in B cells and contributes to the mutation landscape in cancer, such as ...
Benjamin JM Taylor +2 more
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Genomic and serum tumor markers in Egyptian females with and without family cancer history [PDF]
World Cancer Research Journal, 2022 OBJECTIVE: Multiple variables affect the probability of development of cancer. The present study aimed to screen Egyptian females for early prognostic cancer markers such as carcinoembryonic antigen (CEA), the soluble form of transmembrane mucin protein (
H. Salem +7 more
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Investigating the mechanism of action of hemofugal and blood-stasis-expelling soup in the treatment of coronary heart disease based on network pharmacology [PDF]
BIO Web of ConferencesObjective: To investigate the mechanism of action of Xuefu yuyuxu Tang in the treatment of Coronary Heart Disease (CHD) based on network-based pharmacology.
·yusuf Arslan, Ma Yun, Wang Qi
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Current Opinion in Structural Biology, 2012 Nucleic acids are an important class of biological macromolecules that carry out a variety of cellular roles. For many functions, naturally occurring DNA and RNA molecules need to fold into precise three-dimensional structures. Due to their self-assembling characteristics, nucleic acids have also been widely studied in the field of nanotechnology, and ...
Sim, A, Minary, P, Levitt, M
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Frontiers in Pharmacology, 2022 Cisplatin is a widely used and potent anti-neoplastic agent, but severe and inescapable side effects in multiple normal tissues and organs limit its application, especially nephrotoxicity.
Qiang Wang +19 more
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On-Chip DNA Methylation Analysis Using Osmium Complexation
Journal of Nucleic Acids, 2011 The development of a reaction for detecting the presence/absence of one methyl group in a long DNA strand is a chemically and biologically challenging research subject.
Kaori Sugizaki +2 more
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Frontiers in Genetics, 2022 Over 50 million people around the world currently are suffering from Alzheimer’s disease (AD) without any effective therapy. Neuroinflammation plays a pivotal role in AD, which leads us to probe the profile of immune cell infiltration in AD.
Fanmao Jin +6 more
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