Results 11 to 20 of about 6,071,343 (411)

Genomic and serum tumor markers in Egyptian females with and without family cancer history [PDF]

open access: yesWorld Cancer Research Journal, 2022
OBJECTIVE: Multiple variables affect the probability of development of cancer. The present study aimed to screen Egyptian females for early prognostic cancer markers such as carcinoembryonic antigen (CEA), the soluble form of transmembrane mucin protein (
H. Salem   +7 more
doaj   +1 more source

False negative of RT‐PCR and prolonged nucleic acid conversion in COVID‐19: Rather than recurrence

open access: yesJournal of Medical Virology, 2020
A novel coronavirus (COVID-19) pandemic cause by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) threatens the world. We read with interest the recent report by Li et al.
Ai Tang Xiao, Y. Tong, S. Zhang
semanticscholar   +1 more source

A Guide to Nucleic Acid Vaccines in the Prevention and Treatment of Infectious Diseases and Cancers: From Basic Principles to Current Applications

open access: yesFrontiers in Cell and Developmental Biology, 2021
Faced with the challenges posed by infectious diseases and cancer, nucleic acid vaccines present excellent prospects in clinical applications. Compared with traditional vaccines, nucleic acid vaccines have the characteristics of high efficiency and low ...
Furong Qin   +7 more
semanticscholar   +1 more source

DNA priming immunization is more effective than recombinant protein vaccine in eliciting antigen-specific B cell responses

open access: yesEmerging Microbes and Infections, 2021
While DNA prime-protein boost vaccination approach has been widely used in preclinical and clinical studies especially in the field of HIV vaccine development, the exact role of DNA immunization has not been fully identified.
Haiying Li   +5 more
doaj   +1 more source

Overcoming the bottleneck to widespread testing: a rapid review of nucleic acid testing approaches for COVID-19 detection

open access: yesRNA: A publication of the RNA Society, 2020
The current COVID-19 pandemic presents a serious public health crisis, and a better understanding of the scope and spread of the virus would be aided by more widespread testing.
Meagan N. Esbin   +5 more
semanticscholar   +1 more source

Branching Ionizable Lipids Can Enhance the Stability, Fusogenicity, and Functional Delivery of mRNA

open access: yesSmall Science, 2023
Ionizable lipids with branched tails have been used in lipid nanoparticles (LNPs)‐based messenger RNA (mRNA) therapeutics like COVID‐19 vaccines. However, due to the limited commercial availability of branched ingredients, a systematic analysis of how ...
Kazuki Hashiba   +9 more
doaj   +1 more source

Massively multiplexed nucleic acid detection with Cas13

open access: yesNature, 2020
The great majority of globally circulating pathogens go undetected, undermining patient care and hindering outbreak preparedness and response. To enable routine surveillance and comprehensive diagnostic applications, there is a need for detection ...
Cheri M Ackerman   +17 more
semanticscholar   +1 more source

RNA ligase ribozymes with a small catalytic core

open access: yesScientific Reports, 2023
Catalytic RNAs, or ribozymes, catalyze diverse chemical reactions that could have sustained primordial life in the hypothetical RNA world. Many natural ribozymes and laboratory evolved ribozymes exhibit efficient catalysis mediated by elaborate catalytic
Yoko Nomura, Yohei Yokobayashi
doaj   +1 more source

Mfold web server for nucleic acid folding and hybridization prediction

open access: yesNucleic Acids Res., 2003
The abbreviated name, 'mfold web server', describes a number of closely related software applications available on the World Wide Web (WWW) for the prediction of the secondary structure of single stranded nucleic acids.
M. Zuker
semanticscholar   +1 more source

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