Results 21 to 30 of about 6,135,044 (385)
Specificity Determination in Saccharomyces cerevisiae Killer Virus Systems
Microorganisms, 2021 Saccharomyces yeasts are widely distributed in the environment and microbiota of higher organisms. The killer phenotype of yeast, encoded by double-stranded RNA (dsRNA) virus systems, is a valuable trait for host survival. The mutual relationship between
Lina Aitmanaitė +4 more
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Non-canonical DNA structures: Diversity and disease association
Frontiers in Genetics, 2022 A complete understanding of DNA double-helical structure discovered by James Watson and Francis Crick in 1953, unveil the importance and significance of DNA.
Aparna Bansal +4 more
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Experimental Biology and Medicine, 1910 On hydrolysis of yeast nucleic acid the following components had been maintained: adenin, guanin, cytosin, uracil, dribose and phosphoric acid. On the basis of this knowledge and on the basis of the results of the elementary composition of the acid, the composition of the yeast nucleic acid was expressed schematically in the following manner:
P.A. Levene, W. A. Jacobs
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Nucleic Acids Research, 2021 Knowledge of the interactions between proteins and nucleic acids is the basis of understanding various biological activities and designing new drugs. How to accurately identify the nucleic-acid-binding residues remains a challenging task.
Ying Xia +3 more
semanticscholar +1 more source
Regulation of the nucleic acid-sensing Toll-like receptors
Nature reviews. Immunology, 2021 Many of the ligands for Toll-like receptors (TLRs) are unique to microorganisms, such that receptor activation unequivocally indicates the presence of something foreign.
Nicholas A. Lind +4 more
semanticscholar +1 more source
Emerging Microbes and Infections, 2021 While DNA prime-protein boost vaccination approach has been widely used in preclinical and clinical studies especially in the field of HIV vaccine development, the exact role of DNA immunization has not been fully identified.
Haiying Li +5 more
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Branching Ionizable Lipids Can Enhance the Stability, Fusogenicity, and Functional Delivery of mRNA
Small Science, 2023 Ionizable lipids with branched tails have been used in lipid nanoparticles (LNPs)‐based messenger RNA (mRNA) therapeutics like COVID‐19 vaccines. However, due to the limited commercial availability of branched ingredients, a systematic analysis of how ...
Kazuki Hashiba +9 more
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Genomic and serum tumor markers in Egyptian females with and without family cancer history [PDF]
World Cancer Research Journal, 2022 OBJECTIVE: Multiple variables affect the probability of development of cancer. The present study aimed to screen Egyptian females for early prognostic cancer markers such as carcinoembryonic antigen (CEA), the soluble form of transmembrane mucin protein (
H. Salem +7 more
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RNA ligase ribozymes with a small catalytic core
Scientific Reports, 2023 Catalytic RNAs, or ribozymes, catalyze diverse chemical reactions that could have sustained primordial life in the hypothetical RNA world. Many natural ribozymes and laboratory evolved ribozymes exhibit efficient catalysis mediated by elaborate catalytic
Yoko Nomura, Yohei Yokobayashi
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Breathing Life into Polycations [PDF]
, 2008 The lack of efficient delivery systems is still limiting the full therapeutic potential of siRNA. For the purpose of nucleic acid transfer, among other synthetic carrier systems, polycations have been applied.
Meyer, Martin +4 more
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