Results 21 to 30 of about 186,936 (344)

Nucleic acid amplification techniques for the detection of Schistosoma mansoni infection in humans and the intermediate snail host: a structured review and meta-analysis of diagnostic accuracy

open access: yesInternational Journal of Infectious Diseases, 2021
Background: Schistosomiasis is a parasitic disease caused by hematodes of genus Schistosoma. This review evaluated the available nucleic acid amplification techniques for diagnosing S.
Hong-Mei Li   +8 more
doaj   +1 more source

Advanced CRISPR-Cas Effector Enzyme-Based Diagnostics for Infectious Diseases, Including COVID-19

open access: yesLife, 2021
Rapid and precise diagnostic tests can prevent the spread of diseases, including worldwide pandemics. Current commonly used diagnostic methods include nucleic-acid-amplification-based detection methods and immunoassays.
Sangha Kwon, Ha Youn Shin
doaj   +1 more source

Applications of Graphene Quantum Dots in Biomedical Sensors [PDF]

open access: yes, 2020
Due to the proliferative cancer rates, cardiovascular diseases, neurodegenerative disorders, autoimmune diseases and a plethora of infections across the globe, it is essential to introduce strategies that can rapidly and specifically detect the ultralow ...
Altintas, Zeynep, Mansuriya, Bhargav D.
core   +1 more source

Novel immuno-nucleic acid cooperative detection technology for food safety

open access: yesFood and Agricultural Immunology, 2020
The establishment of nucleic acid amplification technology and functional nucleic acid aptamers promote the development of detection techniques. In particular, the detection displayed promise for broader application, as well as improved specificity ad ...
Xinyue Lan, Longjiao Zhu, Wentao Xu
doaj   +1 more source

Recent molecular techniques for the diagnosis of Zika and Chikungunya infections: A systematic review

open access: yesHeliyon, 2022
Zika virus (ZIKV) and Chikungunya virus (CHIKV) are arboviruses that cause important viral diseases affecting the world population. Both viruses can produce remarkably similar clinical manifestations, co-circulate in a geographic region, and coinfections
María C. Cardona-Trujillo   +4 more
doaj   +1 more source

Development of rapid, automated diagnostics for infectious disease: advances and challenges [PDF]

open access: yes, 2009
The last 2 years has seen an exponential rise in the amount of research funding made available for the development of rapid diagnostic devices for infectious agents of medical importance. This review reports on several such projects.
Ince, J, McNally, A
core   +1 more source

Electrical and Electrochemical Monitoring of Nucleic Acid Amplification

open access: yesFrontiers in Bioengineering and Biotechnology, 2015
Nucleic acid amplification is a gold standard technique for analyzing a tiny amount of nucleotides in molecular biology, clinical diagnostics, food safety, and environmental testing.
Tatsuro eGoda   +2 more
doaj   +1 more source

Improving statistical inference on pathogen densities estimated by quantitative molecular methods: malaria gametocytaemia as a case study [PDF]

open access: yes, 2015
BACKGROUND: Quantitative molecular methods (QMMs) such as quantitative real-time polymerase chain reaction (q-PCR), reverse-transcriptase PCR (qRT-PCR) and quantitative nucleic acid sequence-based amplification (QT-NASBA) are increasingly used to ...
A Gelman   +56 more
core   +4 more sources

Low-Cost 3D Printers Enable High-Quality and Automated Sample Preparation and Molecular Detection. [PDF]

open access: yesPLoS ONE, 2016
Most molecular diagnostic assays require upfront sample preparation steps to isolate the target's nucleic acids, followed by its amplification and detection using various nucleic acid amplification techniques.
Kamfai Chan   +8 more
doaj   +1 more source

A novel cassette method for probe evaluation in the designed biochips [PDF]

open access: yes, 2014
A critical step in biochip design is the selection of probes with identical hybridisation characteristics. In this article we describe a novel method for evaluating DNA hybridisation probes, allowing the fine-tuning of biochips, that uses cassettes with ...
Al-humam, Abdulmohsen A.   +7 more
core   +4 more sources

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