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Determination of the Conformation of Nucleic Acids by Electronic CD

1996
The natural and synthetic nucleic acids are polymers of nucleotides that in turn are made up of an aromatic base, a sugar, and a phosphate group. The bases are the chromophores that absorb ultraviolet light to undergo electronic transitions, which begin at 300 nm and continue into the vacuum UV region.
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Conformational penalties: New insights into nucleic acid recognition

Current Opinion in Structural Biology
The energy cost accompanying changes in the structures of nucleic acids when they bind partner molecules is a significant but underappreciated thermodynamic contribution to binding affinity and specificity. This review highlights recent advances in measuring conformational penalties and determining their contribution to the recognition, folding, and ...
Ainan, Geng   +2 more
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