Results 1 to 10 of about 451,143 (385)

Nucleic Acid Conformation Influences Postsynthetic Suzuki-Miyaura Labeling of Oligonucleotides. [PDF]

open access: greenBioconjug Chem, 2020
Chemoselective transformations that work under physiological conditions have emerged as powerful tools to label nucleic acids in cell-free and cellular environments.
Walunj MB, Srivatsan SG.
europepmc   +4 more sources

Modelling aptamers with nucleic acid mimics (NAM): From sequence to three-dimensional docking

open access: yesPLoS ONE, 2022
Aptamers are single-stranded oligonucleotides, formerly evolved by Systematic Evolution of Ligands by EXponential enrichment (SELEX), that fold into functional three-dimensional structures.
Ricardo Oliveira   +5 more
doaj   +3 more sources

Conformational classification of functional nucleic acids [PDF]

open access: bronzeNucleic Acids Symposium Series, 1999
The kink parameters would provide the tolerant aspect for irregular helical structure of nucleic acid. Using these kink parameters, the classification of conformation space was carried for the functional nucleic acid molecules. The kink parameters could afford us the simple structural aspects about the constructive parts of functional molecules.
Satoshi Fujii
openalex   +3 more sources

Nucleic Acid-tagged Peptides: Encoding Libraries and Controlling Dimerization and Conformation

open access: diamondCHIMIA, 2013
Recent progress in the synthesis, screening, and self-assembly of nucleic acid–tagged peptidic libraries is reviewed.
Kalyan K. Sadhu, Nicolas Winssinger
doaj   +3 more sources

Sensing the structural and conformational properties of single-stranded nucleic acids using electrometry and molecular simulations [PDF]

open access: goldScientific Reports
Inferring the 3D structure and conformation of disordered biomolecules, e.g., single stranded nucleic acids (ssNAs), remains challenging due to their conformational heterogeneity in solution.
Rowan Walker-Gibbons   +4 more
doaj   +2 more sources

Nucleic Acid Reactivity and Conformation

open access: hybridJournal of Biological Chemistry, 1973
Robert Shapiro   +3 more
openalex   +2 more sources

Conformations of Single-Stranded Nucleic Acids in Solution [PDF]

open access: bronzeBiophysical Journal, 2017
Alex Plumridge   +2 more
openalex   +2 more sources

Developing Community Resources for Nucleic Acid Structures

open access: yesLife, 2022
In this review, we describe the creation of the Nucleic Acid Database (NDB) at Rutgers University and how it became a testbed for the current infrastructure of the RCSB Protein Data Bank. We describe some of the special features of the NDB and how it has
Helen M. Berman   +2 more
doaj   +1 more source

Effects of 2'-O-methyl nucleotide substitution on EcoRI endonuclease cleavage activities. [PDF]

open access: yesPLoS ONE, 2013
To investigate the effect of sugar pucker conformation on DNA-protein interactions, we used 2'-O-methyl nucleotide (2'-OMeN) to modify the EcoRI recognition sequence -TGAATTCT-, and monitored the enzymatic cleavage process using FRET method.
Guojie Zhao   +4 more
doaj   +1 more source

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