Nucleic Acid Conformation Influences Postsynthetic Suzuki-Miyaura Labeling of Oligonucleotides. [PDF]
Chemoselective transformations that work under physiological conditions have emerged as powerful tools to label nucleic acids in cell-free and cellular environments.
Walunj MB, Srivatsan SG.
europepmc +4 more sources
Modelling aptamers with nucleic acid mimics (NAM): From sequence to three-dimensional docking
Aptamers are single-stranded oligonucleotides, formerly evolved by Systematic Evolution of Ligands by EXponential enrichment (SELEX), that fold into functional three-dimensional structures.
Ricardo Oliveira +5 more
doaj +3 more sources
Conformational classification of functional nucleic acids [PDF]
The kink parameters would provide the tolerant aspect for irregular helical structure of nucleic acid. Using these kink parameters, the classification of conformation space was carried for the functional nucleic acid molecules. The kink parameters could afford us the simple structural aspects about the constructive parts of functional molecules.
Satoshi Fujii
openalex +3 more sources
Nucleic Acid-tagged Peptides: Encoding Libraries and Controlling Dimerization and Conformation
Recent progress in the synthesis, screening, and self-assembly of nucleic acid–tagged peptidic libraries is reviewed.
Kalyan K. Sadhu, Nicolas Winssinger
doaj +3 more sources
Sensing the structural and conformational properties of single-stranded nucleic acids using electrometry and molecular simulations [PDF]
Inferring the 3D structure and conformation of disordered biomolecules, e.g., single stranded nucleic acids (ssNAs), remains challenging due to their conformational heterogeneity in solution.
Rowan Walker-Gibbons +4 more
doaj +2 more sources
Nucleic Acid Reactivity and Conformation
Robert Shapiro +3 more
openalex +2 more sources
Nucleic acid stain-dependent single strand conformation polymorphisms
David R. McKee, M. Scott Thomson
doaj +2 more sources
Conformations of Single-Stranded Nucleic Acids in Solution [PDF]
Alex Plumridge +2 more
openalex +2 more sources
Developing Community Resources for Nucleic Acid Structures
In this review, we describe the creation of the Nucleic Acid Database (NDB) at Rutgers University and how it became a testbed for the current infrastructure of the RCSB Protein Data Bank. We describe some of the special features of the NDB and how it has
Helen M. Berman +2 more
doaj +1 more source
Effects of 2'-O-methyl nucleotide substitution on EcoRI endonuclease cleavage activities. [PDF]
To investigate the effect of sugar pucker conformation on DNA-protein interactions, we used 2'-O-methyl nucleotide (2'-OMeN) to modify the EcoRI recognition sequence -TGAATTCT-, and monitored the enzymatic cleavage process using FRET method.
Guojie Zhao +4 more
doaj +1 more source

