Results 211 to 220 of about 451,143 (385)

Development & Application of Constant pH Molecular Dynamics (CPHMD ) for Investigating pH-mediated Transient Conformational States and Their Effects on Nucleic Acid & Protein Activity.

, 2015
Garrett B. Goh
openalex   +1 more source

Multistrand Structure Prediction of Nucleic Acid Assemblies and Design of RNA Switches.

Nano letters (Print), 2016
Eckart Bindewald, K. Afonin, Mathias Viard, P. Zakrevsky, Taejin Kim, B. Shapiro   +5 more
semanticscholar   +1 more source

Enrichment of Hypermethylated DNA on Chip for Cervical Cancer Detection

Advanced Materials Interfaces, EarlyView.
A microfluidic chip coated with surface‐immobilized methyl binding domain 2 (MBD‐2) protein receptors, is able to bind hypermethylated DNA (hmDNA) from a cancer cell line selectively. Quantification by quantitative polymerase chain reaction (qPCR) shows a 30‐fold enrichment in cervical cancer target DNA.
Ruben W. Kolkman, Birgit M. M. Wever, Jeanne Elisabeth van Dongen, Annina P. van Splunter, Johan G. Bomer, Renske D. M. Steenbergen, Loes I. Segerink, Jurriaan Huskens   +7 more
wiley   +1 more source

RNA Binding Mechanism of the FUS Zinc Finger in Concert with Its Flanking Intrinsically Disordered Region. [PDF]

J Chem Inf Model
Kijima S, Kitao A.
europepmc   +1 more source

Conformational studies of the nucleic acid binding sites for Xenopus transcription factor IIIA.

, 1991
Paul W. Huber, Gerard C. Blobe, Kevin M. Hartmann   +2 more
openalex   +1 more source

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta, Ryan F. Donnelly   +6 more
wiley   +1 more source

Modification of Deoxyribonucleic Acid with Indole-Linked Nucleotides Induces BZ- and Z‑Conformation and Alters Its Sensitivity to Enzymatic Cleavage. [PDF]

ACS Omega
Lingala S, Fisiuk A, Stephen M, Mohanrao R, Klingsberg J, Vecchioni S, Volvovitz ES, Rozhkov S, Mallikaratchy P.   +8 more
europepmc   +1 more source

Design, synthesis, and analysis of conformationally constrained nucleic acids [PDF]

, 1998
Gary D. Glick
openalex   +1 more source

Femtosecond‐Laser‐Fabricated 3D CYTOP Microfluidic Chips Enabling Super‐Resolution Live Imaging of Cell Behavior in Confined Microspaces

Advanced Materials Technologies, EarlyView.
Using two‐photon polymerization of SU‐8 together with mold processing allowed the creation of defect‐free, flexible 3D microfluidic structures with sub‐micrometer precision in CYTOP. The fabricated CYTOP microfluidic chips enabled super‐resolution imaging of cancer cells in the microchannels, clearly visualizing previously undetectable fine structural ...
Koji Sugioka, Mirai Hanzawa, Kotaro Obata, Sota Matsumoto, Masatoshi Takagi, Asako Sakaue‐Sawano, Asako Tosaki, Satoshi Shimozono, Felix Sima, Hiroyuki Kawano, Takuro Tojima, Daisuke Miyashiro, Kazunari Ozasa, Yasutaka Hanada, Godai Miyaji, Akihiko Nakano, Atsushi Miyawaki   +16 more
wiley   +1 more source

Loop-mediated regulation and base flipping drive RNA cleavage by human mitochondrial PNPase. [PDF]

Nucleic Acids Res
Unseld O, Das H, Hällberg BM.
europepmc   +1 more source