Results 261 to 270 of about 451,143 (385)

A comprehensive benchmarking of the AlphaFold3 for predicting biomacromolecules and their interactions. [PDF]

Brief Bioinform
Peng C, Ni W, Liu Q, Hu G, Zheng W.
europepmc   +1 more source

5-HYDROXYPIPERIDINE-2- CARBOXYLIC ACID AS A MONOMERIC CYCLIC SCAFFOLD FOR CONFORMATIONALLY CONSTRAINED PEPTIDE NUCLEIC ACIDS

Светлана В. Ворона, Marina M. Bober, Ammar Al Mustafa   +2 more
openalex   +1 more source

The torsion space nucleic acids molecular mechanics program DUPLEX: Surveying conformation space by potential energy minimization. Progress report

, 1993
Brian E. Hingerty, Suse Broyde
openalex   +1 more source

A Dynamic DNA Nano‐Antioxidant Targeting Galectin‐3 Attenuates Liver Fibrosis via Reducing Macrophage Oxidative Stress

Advanced Science, EarlyView.
This study developed a dynamic DNA nano‐antioxidant (DDN) for Galectin‐3 siRNA delivery, specifically targeting hepatic macrophages to suppress ROS‐driven fibrosis. DDN enhanced hepatic accumulation, restored NRF2 signaling, and attenuated oxidative stress, collagen deposition, and fibrotic progression in a CCl4‐induced cirrhosis model, demonstrating ...
Mengjia Peng, Jianguo Xu, Youjian Hong, Fei Fang, Yan Li, Duo Ci, Bowen Wang   +6 more
wiley   +1 more source

Supramolecular Interactions Modulate RNA:DNA Folding Observed via Nanopore Sensing. [PDF]

Angew Chem Int Ed Engl
Schmidt TT, Earle MK, Patiño-Guillén G, Li Y, Alexii RE, Baumberg JJ, Keyser UF, Platnich CM.   +7 more
europepmc   +1 more source

Engineering Dimensional Configuration of Single‐Atom S‐Cu‐S Sites as Reversible Electron Station for Enhanced Peroxidase‐Mimicking

Advanced Science, EarlyView.
L‐cysteine triggers auto‐assembly of POD‐like 3D biomimetic S‐Cu‐S single‐atom nanozymes on MoS2 (MoCC). MoCC shows 16.3‐fold higher catalytic velocity and 17.9‐fold greater affinity than HRP, enabling efficient •OH generation via enhanced electron inversion and transfer.
Wenjie Ma, Qian He, Jiancheng Sun, Yiqing Chen, Hongfei Su, Ludan Zhang, Xiao He, Yuguang Wang, Changjian Xie, Zhiyong Zhang, Xin Zhou, Yuliang Zhao, Wenyan Yin   +12 more
wiley   +1 more source

Processing of DNA single-strand breaks with oxidatively damaged ends by LIG1. [PDF]

Nucleic Acids Res
Balu KE, Almohdar D, Lerner C, Ratcliffe J, Tang Q, Parwal T, Lee KM, Prakash A, Çağlayan M.   +8 more
europepmc   +1 more source

Probing excited conformational states of nucleic acids by nitrogen CEST NMR spectroscopy

, 2019
Bo Zhao, Jared T. Baisden, Qi Zhang
openalex   +2 more sources

CHB‐Induced Immune Zonation Chaos Elicited LXRα‐mediated Lipid Metabolism Disorders in Kupffer Cells to Induce Cancer Stem Cell Formation

Advanced Science, EarlyView.
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi, Qingyu Li, Jian Li, Jian Bai, Ji Xi, Qi He, Jianglin Zhou, Xuejun Wang, Xiang Song, Xiaoju Li, Xiangpei Yue, Xiaochang Zhang, Zhen Sun, Jiangbo Li, Wen Yang, Yuke Cui, Wenjie Shu, Liang Guo, Shengqi Wang   +18 more
wiley   +1 more source

Chirality-Promoted Chemical Ligation and Reverse Transcription of <i>Acyclic</i> Threoninol Nucleic Acid. [PDF]

J Am Chem Soc
Okita H, Murayama K, Asanuma H.
europepmc   +1 more source