Results 111 to 120 of about 323,426 (336)
A physical model of cell metabolism [PDF]
, 2018 Cell metabolism is characterized by three fundamental energy demands: to sustain cell maintenance, to trigger aerobic fermentation and to achieve maximum metabolic rate.
Fernandez-de-Cossio-Diaz, Jorge +1 more
core +2 more sources
Metal‐Ligand Complexes as Multifunctional Platforms for Photo‐Activated Cancer Therapy
Advanced Science, EarlyView.Metal‐ligand complexes serve as multifunctional platforms for photo‐activated cancer therapy, facilitating photothermal and photodynamic effects through light absorption and reactive oxygen species generation. This review categorizes these complexes by ligand and metal types, examines their roles in combined therapeutic approaches, and explores ...
Jeonga Kim, Saehan Choi, Yoonsung Nam
wiley +1 more source
Primordial RNA Replication and Applications in PCR Technology [PDF]
, 2013 The emergence of self-replication and information transmission in life's origin remains unexplained despite extensive research on the topic. A hypothesis explaining the transition from a simple organic world to a complex RNA world is offered here based ...
Palasek, Stan
core
Capturing the ‘ome’ : the expanding molecular toolbox for RNA and DNA library construction [PDF]
, 2018 All sequencing experiments and most functional genomics screens rely on the generation of libraries to comprehensively capture pools of targeted sequences.
Boone, Morgane +2 more
core +2 more sources
Single‐Droplet Dual‐Target Quantification of circRNA Biomarkers for Colorectal Cancer Screening
Advanced Science, EarlyView.Circular RNAs are crucial in tumorigenesis. This study identifies circCK1γ3 and circWDR37 as dual plasma biomarkers for colorectal cancer (CRC) screening. It is developed Casµchip, a droplet microfluidic chip using Cas13a/b technology to quantify these biomarkers.
Jingsong Xu +11 more
wiley +1 more source
Site‐Specific Disulfide‐Mediated Crosslinking of DNA Nanocubes for Enhanced Biological Applications
Small ScienceThe development of DNA nanotechnology has enabled the creation of diverse nanomaterials with significant potential in biological applications, such as sensing or drug delivery.
Sinan Faiad +5 more
doaj +1 more source
Bio-Protocol, 2019 In the context of precision medicine, the identification of novel biomarkers for the diagnosis of disease, prognosis, predicting treatment outcome and monitoring of treatment success is of great importance.
Florence Mauger, Jörg Tost
doaj +1 more source
Bibliography on inactivation of viruses and rickettsiae by heat [PDF]
Inactivation of viruses and rickettsiae by heat ...
Homann, L. M., Watson, M. S.
core +1 more source
PLoS ONE, 2014 Preventing protein aggregation is a major goal of biotechnology. Since protein aggregates are mainly comprised of unfolded proteins, protecting against denaturation is likely to assist solubility in an aqueous medium. Contrary to this concept, we found denatured total cellular protein mixture from mammalian cell kept high solubility in pure water when ...
Hirokazu Matsushita +8 more
openaire +5 more sources
Advanced Science, EarlyView.This study investigates a highly multivalent mAb platform fusing Laminin‐511 heterotrimerization domains with Fabs and IgG1‐Fc as a non‐hormonal contraceptive. The most potent molecule ‘LamH10’, possessing 10 Fabs, rapidly achieved >99% reduction in progressively motile sperm at just 33µg per dose in sheep, making the laminin‐IgG hybrid platform the ...
Alison Schaefer +8 more
wiley +1 more source