Results 121 to 130 of about 252,695 (308)

Solid Phase Synthesis and TAR RNA-Binding Activity of Nucleopeptides Containing Nucleobases Linked to the Side Chains via 1,4-Linked-1,2,3-triazole

open access: yesBiomedicines
Nucleopeptides (NPs) represent synthetic polymers created by attaching nucleobases to the side chains of amino acid residues within peptides. These compounds amalgamate the characteristics of peptides and nucleic acids, showcasing a unique ability to ...
Piotr Mucha   +6 more
doaj   +1 more source

Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto   +2 more
wiley   +1 more source

Fluorescent and electrochemical paper based dual sensor for simple and low cost detection of human papillomavirus DNA without denaturation

open access: yesScientific Reports
Tedious steps for double-stranded DNA (dsDNA) denaturation into single-stranded DNA (ssDNA) are necessary for most DNA samples for probe-based hybridization assays, which complicates the detection process.
Panon Tungkunaruk   +7 more
doaj   +1 more source

Establishment and Application of MCRV Detection Method for Larvae of Mud Crab, Scylla paramamosain

open access: yesProgress in Fishery Sciences
Mud crab reovirus (MCRV) present in Scylla paramamosain larvae poses notable risks to the late stage of mud crab aquaculture. The cultivation of MCRV-free larvae and prevention of virus transmission at its source have become critical issues that must be ...
Xiyu JIN   +6 more
doaj   +1 more source

Single and dual RPA‐CRISPR/Cas assays for point‐of‐need detection of Stewart's wilt pathogen (Pantoea stewartii subsp. stewartii) of corn and Maize dwarf mosaic virus

open access: yesPest Management Science, Volume 81, Issue 4, Page 1988-1999, April 2025.
Schematic diagram of the single and dual RPA‐CRISPR/Cas12a/13a diagnostic assays for the detection of Pantoea stewartii subsp. stewartii and Maize dwarf mosaic virus. The validated assays provide a useful and sensitive molecular tool for detecting two quarantine pathogens of maize within a minimal resource framework suitable for fast‐tracking the ...
Qian Tian   +6 more
wiley   +1 more source

Atomic‐Precision Symmetry Breaking in Bi‐O‐Ti Sites Enables ROS Generation for Bactericidal and Osteosarcoma Therapy

open access: yesRare Metals, EarlyView.
ABSTRACT Photocatalytic therapy, which generates reactive oxygen species (ROS) upon light irradiation, has garnered significant interest for antibacterial and anticancer applications. This study establishes a doping‐engineered photocatalytic platform for antibacterial activity and precision osteosarcoma therapy by atomically constructing asymmetric Bi ...
Jun Gu   +8 more
wiley   +1 more source

NIR‐Responsive Nano‐Integrated Magnesium Phosphate Cement Promotes Bone Regeneration via Osteoblast‐Exosome‐Osteoclast Crosstalk

open access: yesRare Metals, EarlyView.
ABSTRACT The limited osteogenic capacity of magnesium phosphate cement (MPC) has constrained its biomedical applications, underscoring the necessity to develop MPC with enhanced physical properties and bone‐forming capabilities. In this study, a multifunctional MPC system was developed by incorporating zoledronic acid‐loaded near‐infrared (NIR ...
Bin Wang   +8 more
wiley   +1 more source

Mesoporous Materials for Electrochemical Biosensors: From Broad Structure to Silica Film

open access: yesSmall, EarlyView.
This review showcases how mesoporous materials advance biosensing, spanning from material classes and fabrication strategies to the unique role of silica films as functional sensing platforms. With tunable porosity, high surface area, and versatile chemistry, these materials enhance selectivity and signal amplification in biosensors.
Vinh Khanh Ho   +3 more
wiley   +1 more source

Prevalence of Eight Viruses in Captive Amur Tigers (Panthera tigris altaica) From Harbin, China 中国哈尔滨市圈养东北虎8种病毒的流行

open access: yesWildlife Letters, EarlyView.
The Amur tiger, an endangered flagship species mainly found in the Russia Far East and Northeastern China, holds immense biological importance, and has been listed under the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES).
Wei Xie   +15 more
wiley   +1 more source

Genetic differentiation and adaptive evolution of buff‐tailed bumblebees in Asia

open access: yesInsect Science, EarlyView.
This study investigates the genetic differentiation and local adaptation of the buff‐tailed bumblebee (Bombus terrestris) across its European and Asian populations. Using whole‐genome resequencing, we identified distinct genetic differences between populations, with Asian B. terrestris representing a unique genetic resource.
Long Su   +14 more
wiley   +1 more source

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