Results 11 to 20 of about 114,253 (306)

Developing predictive hybridization models for phosphorothioate oligonucleotides using high-resolution melting.

open access: yesPLoS ONE, 2022
The ability to predict nucleic acid hybridization energies has been greatly enabling for many applications, but predictive models require painstaking experimentation, which may limit expansion to non-natural nucleic acid analogues and chemistries.
Siyuan S Wang   +3 more
doaj   +1 more source

Application of Graphene FET Nucleic Acid Biosensor in Human Motion Measurement [PDF]

open access: yesInternational Journal Bioautomation, 2018
In order to explore the application of graphene field effect transistor (FET) nucleic acid biosensor, the sensitivity and selectivity of nano FET biosensor detection are improved by the large physical surface ratio, high electron mobility, excellent ...
Hang Yin
doaj   +1 more source

Protein-Based Anchoring Methods for Nucleic Acid Detection in Lateral Flow Format Assays

open access: yesMicromachines, 2023
The use of lateral flow assays to detect nucleic acid targets has many applications including point-of-care diagnostics, environmental monitoring, and food safety.
Kira Hallerbach   +6 more
doaj   +1 more source

Nucleic Acid Hybridization [PDF]

open access: yes, 2020
Abbreviations -- Preface -- 1. Introduction to nucleic acid hybridization -- Structure of nucleic acids -- Forces stabilizing DNA structure -- Mismatched base pairs -- Stability of nucleic acids -- Effects of pH -- Effects of temperature -- Renaturation and hybridization -- 2.
openaire   +3 more sources

Highly efficient and robust π-FISH rainbow for multiplexed in situ detection of diverse biomolecules

open access: yesNature Communications, 2023
Fluorescence in situ hybridization (FISH) methods with high sensitivity are needed. Here the authors develop multiplex πFISH rainbow to detect a range of biomolecules; they also combine this with the hybridization chain reaction to develop πFISH ...
Yingfeng Tao   +17 more
doaj   +1 more source

Glycerol Reduces Cross Hybridization on Nitrocellulose Membrane

open access: yesJurnal Sain Veteriner, 2020
Lateral flow assay (LFD) based nucleic acid lateral flow (NALF)  method has been developed recently. The method met point of care testing (POCT) as simple and rapid procedures, less equipment, and can be performance by less skilled technician. NALF based
Narendra Yoga Hendarta   +3 more
doaj   +1 more source

Nucleic acid nanoassembly-enhanced RNA therapeutics and diagnosis

open access: yesActa Pharmaceutica Sinica B, 2023
RNAs are involved in the crucial processes of disease progression and have emerged as powerful therapeutic targets and diagnostic biomarkers. However, efficient delivery of therapeutic RNA to the targeted location and precise detection of RNA markers ...
Mengnan Zhao   +8 more
doaj   +1 more source

Serotype Specific Sequence for Multi Test Line Nucleic Acid Lateral Flow Development

open access: yesJurnal Sain Veteriner, 2021
Dengue virus that causes dengue fever and dengue shock syndrome has 4 different serotypes. Serotyping is needed for diagnosing and surveillance activities of disease spreaders.
Narendra Yoga Hendarta   +3 more
doaj   +1 more source

Nucleic Acid Analysis Using Multifunctional Hybridization Sensors

open access: yesProceedings, 2017
Hybridization of nucleic acid probes remains one of the most common strategies for sensing of [...]
Dmitry M. Kolpashchikov
doaj   +1 more source

Nucleic Acid Hybrids as Advanced Antibacterial Nanocarriers [PDF]

open access: yesPharmaceutics, 2020
Conventional antibiotic therapy is often challenged by poor drug penetration/accumulation at infection sites and poses a significant burden to public health. Effective strategies to enhance the therapeutic efficacy of our existing arsenal include the use of nanoparticulate delivery platforms to improve drug targeting and minimize adverse effects ...
Sybil Obuobi, Nataša Škalko-Basnet
openaire   +4 more sources

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