Results 191 to 200 of about 34,544 (276)

The Possible Crystallization Process in the Origin of Bacteria, Archaea, Viruses, and Mobile Elements. [PDF]

Biology (Basel)
Yoshimura A, Seki M.
europepmc   +1 more source

Proteolysis‐Targeting Chimera (PROTAC): Current Applications and Future Directions

MedComm, Volume 6, Issue 10, October 2025.
PROTACs are reshaping drug discovery through targeted protein degradation. Clinical programs now extend to prostate, breast, lung, hematologic, and solid tumors, with key targets including AR, ER, BTK, STAT3, Bcl‐xL, BRD9, Kras, and so on. These degraders overcome resistance, broaden therapeutic scope, and provide solutions for “undruggable” proteins ...
Gang Fan, Shilin Chen, Qingping Zhang, Na Yu, Ziyang Shen, Zhaoji Liu, Weiming Guo, Zhihan Tang, Jing Yang, Miao Liu   +9 more
wiley   +1 more source

Regulation of Protein Transport in Functionalized PET Nanopores. [PDF]

J Phys Chem B
Kong J, Jahani R, Zheng H, Zhou S, Chen J, Munusamy S, Zhang Y, Guan X.   +7 more
europepmc   +1 more source

Hydrogel Microspheres as Versatile Platforms for Biomedical Research: Design, Properties, and Applications

MedComm, Volume 6, Issue 10, October 2025.
Schematic diagram illustrating the comprehensive landscape of hydrogel microspheres (HMs). (A) The components of HMs. (B) Preparation technologies employed in fabricating HMs. (C) The diverse applications of HMs across different fields. (D) The therapeutic applications of HMs in the treatment of various systemic diseases, demonstrating their potential ...
Meng Yang, Yuanyuan Shi, Feng Wang, Xin Zhang, Jiayi Shao, Fan Yang, Hao Sun, Chong Zhang, Zheng Zhou, Jianyong Huang, Pengyu Lv, Patrick Shu‐Hang Yung, Jin Cheng, Hong‐Jie Huang, Jian‐Quan Wang   +14 more
wiley   +1 more source

Design of mismatch closure for enhanced specificity in DNA strand displacement reactions. [PDF]

Nucleic Acids Res
Yu H, Han X, Zhang L, Yin N, Wang L, Lv K, Wu Y, Bai D, Wang W, Huang Y, Hu X, Weng Z, Zhang C, Yang G, Chen T, Xie G.   +15 more
europepmc   +1 more source

Programming Directional Strand Polymerization on DNA Origami for Logic Computing

Small Structures, Volume 6, Issue 10, October 2025.
A directional strand polymerization‐based approach is established for constructing logic gates on DNA origami. Switchable DNA hairpins are assembled on DNA origami to serve as monomers to mediate directional molecular signal transmission, based on which the modular assembly of DNA logic gates with feature sizes as small as ≈10 nm is realized.
Zimu Li, Yaya Hao, Yuqing Tang, Chenyun Sun, Jianing Cheng, Kai Xia, Fei Wang, Xiaolei Zuo, Chunhai Fan, Hui Lv   +9 more
wiley   +1 more source

DNA Sequential Logic Circuits for Reversible Counters and Dynamic Biomolecular Sensing. [PDF]

Adv Sci (Weinh)
Xie T, Li C, Hu M, Zhong X, Xiao J, Zhang Z, Wang Z, Wu T.   +7 more
europepmc   +1 more source

Enhancing Dermal Absorption of Cosmeceuticals: Innovations and Techniques for Targeted Skin Delivery

Journal of Cosmetic Dermatology, Volume 24, Issue 10, October 2025.
ABSTRACT Background As beauty consumption upgrades and skincare concepts evolve toward science‐backed efficacy, the field of cosmetology has put forward higher requirements for the dermal absorption efficiency of efficacious products. Notably, amid the global medical aesthetics market's 12.8% Compound Annual Growth Rate (projected to reach $35,327.5 ...
Yichao Peng, Lixia Yue, Yuanhua Cong
wiley   +1 more source

Mechanism of DNA Chemical Denaturation. [PDF]

ACS Omega
Ostrovsky DA, Ostrovsky MV.
europepmc   +1 more source

Discovery and Characterization of Uracil Derivatives Targeting the Set-and-Ring Domain of UHRF1. [PDF]

J Chem Inf Model
Akrani I, Driva D, Tsakalidis E, Mozumdar N, Mavridi D, Panara A, Epiphaniou K, Chalkiadaki M, Wright AF, Halabalaki M, Tsoka A, Zoidis G, Vorgias C, Sproul D, Gikas E, Kriaucionis S, Mikros E, Myrianthopoulos V.   +17 more
europepmc   +1 more source