Results 191 to 200 of about 215,794 (272)

Identification of insertion sites for the integrative and conjugative element Tn916 in the Bacillus subtilis chromosome. [PDF]

PLoS One
Bean EL, Smith JL, Grossman AD.
europepmc   +1 more source

Sequence-Specific Free Energy Changes in DNA/RNA Induced by a Single LNA-T Modification in Antisense Oligonucleotides. [PDF]

Int J Mol Sci
Tomita-Sudo E, Akita T, Sakimoto N, Tahara-Takamine S, Kawakami J.   +4 more
europepmc   +1 more source

Contemporary eDNA methods complement conventional microscopy in zooplankton diet studies: Case study with American lobster postlarvae. [PDF]

PLoS One
Ascher A, Countway PD, Sleith RS, Morris C, Haley C, Fields DM, Wahle RA.   +6 more
europepmc   +1 more source

Induction and Manipulation of Biomolecular Condensates Through Spatially Heterogeneous Solution Conditions. [PDF]

Chembiochem
Buell AK.
europepmc   +1 more source

Thermodynamics and Kinetics‐Directed Regulation of Nucleic Acid‐Based Molecular Recognition

Small Methods
Nucleic acid‐based molecular recognition plays crucial roles in various fields like biosensing and disease diagnostics. To achieve optimal detection and analysis, it is essential to regulate the response performance of nucleic acid probes or switches to ...
Yihao Liu, Zihan Zhao, Yuqi Zeng, Minze He, Yifan Lyu, Quan Yuan   +5 more
semanticscholar   +4 more sources

[24] Thermodynamics of ligand-nucleic acid interactions

Methods in Enzymology, 1992
Ligand-and protein-DNA equilibria are extremely sensitive to solution conditions (e.g., salt, temperature, and pH), and, in general, the effects of different solution variables are interdependent (i.e., linked). As a result, an assessment of the basis for the stability and specificity of ligand-or protein-DNA interactions requires quantitative studies ...
Timothy M. Lohman, David P. Mascotti
semanticscholar   +5 more sources

Atomistic Investigation of the Effect of Incremental Modification of Deoxyribose Sugars by Locked Nucleic Acid (β-d-LNA and α-l-LNA) Moieties on the Structures and Thermodynamics of DNA–RNA Hybrid Duplexes

Journal of Physical Chemistry B, 2014
Chemically modified oligonucleotides offer many possibilities in utilizing their special features for a vast number of applications in nucleic acid based therapies and synthetic molecular biology.
Suresh Gorle, U. Deva Priyakumar
openalex   +2 more sources

Statistical thermodynamics of nucleic acid melting transitions with coupled binding equilibria

Biopolymers, 1971
AbstractEquations are developed to describe the shift in the temperature of the helix–coil transition when small molecules bind to nucleic acids. Included are high polymers, oligonucleotides, and oligomer–polymer interactions. The equations prescribe simple ways of plotting experimental data to evaluate transition and binding parameters.
Donald M. Crothers
semanticscholar   +5 more sources

Native Characterization of Noncanonical Nucleic Acid Thermodynamics via Programmable Dynamic DNA Chemistry

Journal of the American Chemical Society
Folding thermodynamics, quantitatively described using parameters such as ΔGfold°, ΔHfold°, and ΔSfold°, is essential for characterizing the stability and functionality of noncanonical nucleic acid structures but remains difficult to measure at the ...
Yuqin Wu, Guan A. Wang, Qianfan Yang, Feng Li   +3 more
openalex   +2 more sources