Results 121 to 130 of about 23,431 (250)

Molecular Links Between Heat Stress and DNA Damage Response in Plants

Plant, Cell &Environment, EarlyView.
ABSTRACT Climate change poses a major threat to agricultural productivity and, consequently, to global food security. Among the consequences of climate change, heat stress (HS) has emerged as a critical factor limiting crop performance. This has stimulated extensive research over the past decade to elucidate the molecular and physiological mechanisms ...
Adrian Calves‐Ubach, Miriam Szurman‐Zubrzycka   +1 more
wiley   +1 more source

Oxidatively Damaged Nucleobases in Duplex DNA Oligomers: Reaction at Thymine−Thymine Mispairs

, 2016
Oxidatively Damaged Nucleobases in Duplex DNA Oligomers: Reaction at Thymine−Thymine ...
Joshy Joseph (1494178), Gary B. Schuster (10738)   +1 more
core   +1 more source

Perturbation of Spermine Homoeostasis Uncouples Hypersensitive Cell Death From Systemic Plant Immunity

Plant, Cell &Environment, EarlyView.
ABSTRACT Polyamines are key regulators of plant stress responses, yet their contribution to coordinating local immune responses with systemic immunity remains poorly understood. Here, we investigated how spermine (Spm) homeostasis influences local and systemic defence responses in Arabidopsis thaliana following inoculation with Pseudomonas syringae pv.
Jiaqi Zhao, Kostadin E. Atanasov, Olga Jauregui, Rubén Alcázar   +3 more
wiley   +1 more source

Nitroalkylation Mediated by Nitro‐Fatty Acids Is Involved in Key Physiological Processes During Arabidopsis thaliana Development

Plant, Cell &Environment, EarlyView.
ABSTRACT Nitro‐fatty acids (NO2‐FAs) are potent electrophiles that react with nucleophilic residues in proteins (cysteines, histidines and lysines) via a process known as nitroalkylation. This reversible post‐translational modification (PTM) functions as a selective signalling mechanism by modulating the structure, transport, and catalysis of target ...
Lorena Aranda‐Caño, Raquel Valderrama, Mounira Chaki, Juan Carlos Begara‐Morales, José Rafael Pedrajas, Manuel Melguizo, Matín Moret, Aureliano Bombarely, Francisco Luque, Juan Bautista Barroso   +9 more
wiley   +1 more source

Probing the molecular determinants of emission enhancement in RNA aptamer–metal complex systems

Photochemistry and Photobiology, EarlyView.
Light up aptamer: fluorophore pairs are widely used in sensing and imaging, with coordination complex fluorophores providing specific benefits due to their long‐lived emission. Here, we examined key structural and electronic features of these metal complexes to identify the requirements for productive engagement with an RNA aptamer.
Sarah M. Kriger, Joseph Spiconardi, Nathan Ennist, Edith C. Glazer   +3 more
wiley   +1 more source

Recent Advances in Reversed‐Phase Liquid Chromatography for Therapeutic Oligonucleotide and Conjugate Characterization: From Ion‐Pairing to Green Analytical Approaches

Analytical Science Advances, Volume 7, Issue 2, December 2026.
ABSTRACT Therapeutic oligonucleotides (ONs) have rapidly emerged as a novel class of treatments in the pharmaceutical industry, with over 25 medicines approved in the past decade. Ion‐pair reversed‐phase liquid chromatography coupled with mass spectrometry (IP‐RPLC‐MS) is widely used method for ON characterization.
Quang‐Dong Bui, Weronika Hewelt‐Belka, Tiny Deschrijver, Martin Gilar, Sebastiaan Eeltink   +4 more
wiley   +1 more source

Beyond a dual role: how Purpureocillium lilacinum reprograms citrus metabolism for integrated biocontrol and growth promotion

Journal of the Science of Food and Agriculture, Volume 106, Issue 15, Page 9778-9793, December 2026.
Abstract BACKGROUND Plants harbor complex microbial communities that are fundamental to their health and productivity. Among them, endophytic fungi such as Purpureocillium lilacinum establish mutualistic associations, offering dual benefits as plant growth promoters and biocontrol agents.
Sana Bouzembila, Kamel Charaabi, Haytham Hamden, Salma Fadhel, Nesrine Tanfouri, Meriem Msaad Guerfali   +5 more
wiley   +1 more source

Individual Identification of DNA Nucleobases on Atomically Thin Black Phosphorene Nanoribbons: van der Waals Corrected Density Functional Theory Calculations

, 2019
Monolayer-based nanodevices hold great promise for the next-generation sequencing (biomolecular sensing/DNA sequencing)-based applications. In this study, we have investigated the interaction of the four nucleobases (adenine, guanine, thymine, and ...
Rameshwar L. Kumawat (7339496), Rameshwar L. Kumawat, Biswarup Pathak (1491820), Biswarup Pathak   +3 more
core   +1 more source

Multimodal Exploratory Analysis of Persistent Diabetic Macular Edema: Integrating Aqueous Humour Metabolomics, Clinical and OCT Features

Diabetes, Obesity and Metabolism, Volume 28, Issue 12, Page 11632-11642, December 2026.
ABSTRACT Purpose This exploratory study integrates aqueous humour metabolomic data with clinical and imaging features to examine candidate biomarkers and characterize multimodal patterns associated with persistent diabetic macular edema (pDME). Methods In this prospective cohort study, DME patients were treated with monthly anti‐VEGF injections over 3 ...
Yunhan Tao, Huimin Yu, Yunxi Ma, Mingzhu Yuan, Guochong Chen, Jun Liu, Xi Chen, Xufang Sun   +7 more
wiley   +1 more source

The Dual Nature of RNA Ligation and Degradation by T4 RNA Ligase 1: Insights Into an AMP‐Driven, Nucleobase‐Dependent Reverse Reaction

ChemBioChem, Volume 27, Issue 21, 12 November 2026.
T4 RNA Ligase 1 (Rnl1) not only ligates RNA but also catalyzes a reverse reaction leading to RNA degradation. This degradation occurs under standard ligation conditions and shows sequence preference. Here, we investigated whether the reverse reaction can be controlled by optimizing buffer conditions to improve reliability of Rnl1‐based experiments ...
Nozomi Adachi, Wataru Takahagi, Shohei Terazawa, Ryoji F. Abe, Nao Masuda, Kosuke Fujishima   +5 more
wiley   +1 more source