Results 131 to 140 of about 23,431 (250)

Multienzyme Cascade Reactions: Compatibility, Cooperativity, and Control

Advanced Synthesis &Catalysis, Volume 368, Issue 21, 3 November 2026.
Multienzyme cascade reactions are sequences of telescoped biotransformations that avoid the isolation of intermediates and offer significant efficiency advantages over traditional multistep routes. This review article highlights recent examples of multienzyme cascades and explores how their success depends on the consideration of compatibility ...
Isabella E. E. Kroschel, Wolfgang Kroutil, Joerg H. Schrittwieser   +2 more
wiley   +1 more source

Phototriggers for Nucleobases with Improved Photochemical Properties

, 2016
Synthesis and photochemical properties of new photoremovable protecting groups for nucleobases are described. Four caged 2‘-deoxycytidines (dCs) were synthesized, and their photochemical properties were measured under simulated physiological conditions ...
Takayoshi Watanabe (734601), Toshiaki Furuta (1490857), Satoshi Tanabe (2469217), Chie Matsuba (2469214), Jun Sakyo (2469211)   +4 more
core   +1 more source

Introduction of a Double‐Headed Nucleotide Into G‐Quadruplex DNA: Position‐Dependent Stabilization and Structural Insights

Chemistry – A European Journal, Volume 32, Issue 41, 3 November 2026.
A double‐headed bis‐guanine (G) nucleotide (GG) was evaluated as a noncanonical building block in G‐quadruplexes (G4s). Biophysical and computational analyses reveal that GG can directly participate in G‐tetrads and strongly stabilize G4s in a position‐ and topology‐dependent manner. These findings establish design rules for using GG to engineer highly
Krista Urup, Peter Reinholdt, Kasper Munch Beck, Michael Petersen, Jean‐Louis Mergny, Poul Nielsen   +5 more
wiley   +1 more source

Dynamic Operations in Macromolecular Data Storage

Angewandte Chemie, Volume 138, Issue 44, 26 October 2026.
With the exponential growth of digital data and the limitations of conventional silicon‐based storage and computing technologies, macromolecular data storage, the practice of encoding digital information within large, complex molecules like DNA or synthetic polymers, has emerged as a scalable and sustainable alternative to traditional digital ...
Jakub Ossowski, Oskar Affenberger, Jean‐François Lutz, Maria Nerantzaki   +3 more
wiley   +2 more sources

nucleobase lesion

Citation: 'nucleobase lesion' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.09711 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

The Formation of Nucleobases from the Irradiation of Purine in Astophysical Ices and Comparisons with Meteorites. [PDF]

, 2016
N-heterocycles have been identified in meteorites and their extraterrestrial origins are suggested by isotopic ratio measurements. Although small N- heterocycles have not been detected in the interstellar medium (ISM), recent experiments in our lab have ...
Sandford, S. A., Nuevo, M., Materese, C. K.   +2 more
core  

Multivalent RNA‐Cleaving Agents on a Cubic Octameric Silsesquioxane Core

Chemistry – A European Journal, Volume 32, Issue 41, 3 November 2026.
RNA‐cleaving agents on a cubic octameric silsesquioxane core were synthesized and characterized. Several catalytic systems of these structures were screened using hexaribonucleotide models. The best systems were then further used to study their catalytic efficiency in cleaving a HER2 mRNA model sequence. The induced cleavage sites were also determined.
Hanni Haapsaari, Iris Tuomi, Pasi Virta
wiley   +1 more source

Nano Borophene as a Programmable 2D Scaffold for Organized DNA Assembly and Long‐Range Energy Transfer

Advanced Functional Materials, Volume 36, Issue 88, 2 November 2026.
Borophene is introduced as a programmable 2D bio‐interface that organizes DNA through dual boron–sulfur and nucleobase interactions. This molecular architecture enables efficient long‐range nanosurface energy transfer, establishing new design principles for functional nano–bio interfaces and amplification‐free optical biosensing.
Teresa Aditya, Pranay Saha, John M. Sansalone, Shraddha Krishnakumar, Matthew Molinaro, André J. van der Vlies, Nada Maher, Adrienne Griffiths, Zakhro Zakirova, Ketan Dighe, Narayana R. Aluru, Dipanjan Pan   +11 more
wiley   +1 more source

Sublimation thermodynamics of nucleobases derived from fast scanning calorimetry

, 2020
© 2020 the Owner Societies. The five fundamental units of the genetic code: Uracil (U), thymine (T), cytosine (C), adenine (A) and guanine (G) are known for extremely low vapor pressure and low thermal stability at elevated temperatures.
Zaitsau D.H., Buzyurov A.V., Abdelaziz A., Verevkin S.P., Schick C.   +4 more
core  

Controllable DNA Condensation by Mixed Cationic Gemini/Nonionic Surfactant Systems: Structure, Thermodynamics, and Cytotoxicity

Journal of Surfactants and Detergents, Volume 29, Issue 6, Page 969-979, November 2026.
ABSTRACT Controllable DNA condensation is important for nucleic‐acid packaging and non‐viral gene‐delivery systems. This study aimed to determine how the composition of mixed nonionic C12E10 and cationic gemini C12C6C12Br2 surfactants regulates DNA condensation, structure, thermodynamics, and cytotoxicity.
Bo Wang, Linyi Zhu, Yaxun Fan, Yilin Wang   +3 more
wiley   +1 more source