Results 91 to 100 of about 84,247 (263)
Viable porcine arteriviruses with deletions proximal to the 3 ' end of the genome [PDF]
, 2001 In order to obtain attenuated live vaccine candidates of porcine reproductive and respiratory syndrome virus (PRRSV), a series of deletions was introduced at the 3′ end of the viral genome using an infectious cDNA clone of the Lelystad virus isolate. RNA
Rottier, P.J.M. +3 more
core
The Nucleocapsid Protein of Human Coronavirus NL63
PLOS ONE, 2015 Human coronavirus (HCoV) NL63 was first described in 2004 and is associated with respiratory tract disease of varying severity. At the genetic and structural level, HCoV-NL63 is similar to other members of the Coronavirinae subfamily, especially human coronavirus 229E (HCoV-229E).
Zuwała, Kaja +14 more
openaire +5 more sources
Establishment of Humanized EFNB2/B3 Murine Models for Investigating Nipah Virus Pathogenesis
Animal Research and One Health, EarlyView.ABSTRACT Nipah virus (NiV) is a zoonotic paramyxovirus classified as a WHO priority pathogen, which causes severe respiratory disease and encephalitis in humans with high mortality. Currently, no licensed vaccines or specific antiviral therapies are available.
Wei Dong +6 more
wiley +1 more source
A Polyamide Inhibits Replication of Vesicular Stomatitis Virus by Targeting RNA in the Nucleocapsid [PDF]
, 2018 Polyamides have been shown to bind double-stranded DNA by complementing the curvature of the minor groove and forming various hydrogen bonds with DNA. Several polyamide molecules have been found to have potent antiviral activities against papillomavirus,
Ryan H. Gumpper +11 more
core +1 more source
Animal Research and One Health, EarlyView.Seven‐year surveillance reveals a cold‐adapted OsHV‐1 lineage in blood clams, with disease onset at 13°C—3–5°C lower than in oysters—and identifies asymptomatic carriers and facility effluent as key transmission routes. ABSTRACT Ostreid herpesvirus 1 (OsHV‐1) poses a major threat to bivalve aquaculture, but its impact on blood clams (Anadara ...
Xiang Zhang +7 more
wiley +1 more source
A single domain antibody-based Luminex assay for the detection of SARS-CoV-2 in clinical samples
Frontiers in ImmunologyWithin the past decade, single domain antibodies (sdAbs) have been recognized as unique affinity binding reagents that can be tailored for performance in a variety of immunoassay formats.
Ellen R. Goldman +9 more
doaj +1 more source
Purification of nucleocapsid of tospoviruses from Chenopodium quinoa leaves v1
, 2017 Purification of nucleocapsid of tospoviruses from Chenopodium quinoa leaves
Tsung-Chi Chen
core +1 more source
RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging
Biological Reviews, EarlyView.ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad +5 more
wiley +1 more source
Nucleocytoplasmic transport of nucleocapsid proteins of enveloped RNA viruses [PDF]
, 2015 Most viruses with non-segmented single stranded RNA genomes complete their life cycle in the cytoplasm of infected cells. However, despite undergoing replication in the cytoplasm, the structural proteins of some of these RNA viruses localize to the ...
Erin J. Walker +9 more
core +2 more sources
Budding of a Retrovirus: Some Assemblies Required
Viruses, 2020 One of the most important steps in any viral lifecycle is the production of progeny virions. For retroviruses as well as other viruses, this step is a highly organized process that occurs with exquisite spatial and temporal specificity on the cellular ...
Kevin M. Rose +2 more
doaj +1 more source