Results 111 to 120 of about 69,939 (210)
Toward a Functional Cure for Chronic Hepatitis B: Current Landscape and Future Directions in Japan
Hepatology Research, Volume 56, Issue 6, Page 903-913, June 2026.Hepatitis B is a viral liver infection that can become chronic, increasing the risk of developing liver cancer and liver failure. Because current treatments rarely cure these problems, researchers are now focusing on a functional cure in which the virus becomes undetectable in blood and stays that way, even after the treatment ends.
Yutaka Handa +2 more
wiley +1 more source
Activation of the Lectin Pathway Drives Persistent Complement Dysregulation in Long COVID
Immunology, Volume 178, Issue 2, Page 261-268, June 2026.The complement cascade, a series of blood proteins that assists in the recognition and neutralisation of pathogens, either independently or in conjunction with antibodies, is persistently activated in patients with long COVID. We found that blood plasma samples from patients with long COVID contained elevated concentrations of the mannan‐binding lectin‐
Samuel B. K. Keat +14 more
wiley +1 more source
Frontiers in MicrobiologyProtein modification by the ubiquitin-like protein ISG15 (ISGylation) plays a crucial role in the immunological defense against viral infection. During severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, innate immune signaling ...
Wonjin Bang +10 more
doaj +1 more source
Influenza and Other Respiratory Viruses, Volume 20, Issue 6, June 2026.ABSTRACT Background Genomic surveillance is central to tracking SARS‐CoV‐2 evolution, variant replacement, and transmission dynamics. In Senegal, the Institut Pasteur de Dakar generated one of the largest national longitudinal SARS‐CoV‐2 genomic datasets, offering a unique view of viral spread from the first pandemic wave to the post‐Omicron period ...
Ndeye Awa Ndiaye +21 more
wiley +1 more source
ChemMedChem, Volume 21, Issue 10, 27 May 2026.A protocol guided by ligand‐based pharmacophore modeling and structure‐based virtual screening enabled the identification of 1H‐pyrazol‐5‐ol derivatives as novel inhibitors of the SARS‐CoV‐2 spike protein. The lead inhibitors, C‐3 and C‐4, could serve as templates for the design of potent antiviral agents targeting viral entry into host cells ...
Timoteo Delgado‐Maldonado +5 more
wiley +1 more source
Hepatitis B Virus Nucleocapsid Assembly
Journal of Molecular BiologyHepatitis B virus (HBV), the prototypical member of the Hepadnaviridae family, is a DNA virus that replicates its genome through reverse transcription of a pregenomic RNA (pgRNA) precursor. The selective packaging of pgRNA and viral polymerase (Pol) into assembling capsids formed by the viral core protein-a process known as nucleocapsid assembly-is an ...
Hong, Xupeng +2 more
openaire +2 more sources
Tamm Plasmon Resonance Responsiveness to SARS‐CoV‐2 Virus‐Like Particles
Nanophotonics, Volume 15, Issue 10, 27 May 2026.This work presents a Tamm plasmon device combining a SiO2/TiO2 Bragg reflector and nanostructured silver to detect SARS‐CoV‐2 virus‐like particles through resonance attenuation captured by a displacement angle. Optical characterizations, controls experiments, and mechanistic insights highlight structure‐dependent interactions, and suggest applications ...
Andrea Rossini +5 more
wiley +1 more source
Antibodies to Nucleocapsid Are Not Diagnostic for Long COVID
Microbiology Spectrum, 2023 Brandt, C. T. +3 more
openaire +5 more sources